Publications by authors named "Shawn Lyons"

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G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides.
Prakash Kharel, Nupur Bhatter, Safiyah Zubair, Shawn M Lyons, Paul J Anderson

Nucleic Acids Res· June 2025

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G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides.
Prakash Kharel, Nupur Bhatter, Safiyah Zubair, Shawn Lyons, Paul J Anderson

bioRxiv· December 2024

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Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis.
Patrick T Keiser, Wenhan Zhang, Michael Ricca, Alan Wacquiez, Autumn Grimins, Shawn M Lyons

Antiviral Res· October 2024

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Inhibition of K63 ubiquitination by G-Protein pathway suppressor 2 (GPS2) regulates mitochondria-associated translation.
Yuan Gao, Julian Kwan, Joseph Orofino, Giulia Burrone, Sahana Mitra, Shawn M Lyons

Pharmacol Res· September 2024

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Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage.
Nupur Bhatter, Vivek M Advani, Yoshika Takenaka, Shawn M Lyons, Yasutoshi Akiyama

bioRxiv· September 2024

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Stress granule-mediated sequestration of EGR1 mRNAs correlates with lomustine-induced cell death prevention.
Marta Leśniczak-Staszak, Paulina Pietras, Marcin Ruciński, Ryan Johnston, Mateusz Sowiński, Shawn M Lyons

J Cell Sci· June 2024

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The 3' Untranslated Regions of Ebola Virus mRNAs Contain AU-Rich Elements Involved in Posttranscriptional Stabilization and Decay.
Emily V Nelson, Stephen J Ross, Judith Olejnik, Adam J Hume, Dylan J Deeney, Shawn M Lyons

J Infect Dis· November 2023

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The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.
Rhiannon B Werder, Kayleigh A Berthiaume, Carly Merritt, Marissa Gallagher, Carlos Villacorta-Martin, Shawn M Lyons

Am J Hum Genet· October 2023

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The exoribonuclease XRN2 mediates degradation of the long non-coding telomeric RNA TERRA.
Matthew Reiss, Joshua Keegan, Anne Aldrich, Shawn M Lyons, Rachel Litman Flynn

FEBS Lett· July 2023

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Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA.
Max Paget, Cristhian Cadena, Sadeem Ahmad, Hai-Tao Wang, Tristan X Jordan, Shawn M Lyons

Mol Cell· April 2023

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Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.
Yasutoshi Akiyama, Shawn M Lyons, Marta M Fay, Yoshihisa Tomioka, Takaaki Abe

Front Mol Biosci· March 2022

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Translation inhibition and suppression of stress granules formation by cisplatin.
Paulina Pietras, Anaïs Aulas, Marta M Fay, Marta Leśniczak-Staszak, Mateusz Sowiński, Shawn M Lyons

Biomed Pharmacother· January 2022

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Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity.
Witold Szaflarski, Marta Leśniczak-Staszak, Mateusz Sowiński, Sandeep Ojha, Anaïs Aulas, Shawn M Lyons

Nucleic Acids Res· January 2022

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Correction: Fernandes et al. Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation. 2020, , 1367.
Nikita Fernandes, Luke Nero, Shawn M Lyons, Pavel Ivanov, Telsa M Mittelmeier

Biomolecules· December 2021

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MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells.
Paulina Pietras, Marta Leśniczak-Staszak, Aldona Kasprzak, Małgorzata Andrzejewska, Karol Jopek, Shawn M Lyons

Int J Mol Sci· November 2021

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SDE2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing.
Jess Floro, Anqi Dai, Abigail Metzger, Alexandra Mora-Martin, Neil J Ganem, Shawn M Lyons

Nucleic Acids Res· September 2021

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Ryan M Hekman, Adam J Hume, Raghuveera Kumar Goel, Kristine M Abo, Jessie Huang, Shawn M Lyons

Mol Cell· January 2021

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.
Ryan M Hekman, Adam J Hume, Raghuveera Kumar Goel, Kristine M Abo, Jessie Huang, Shawn M Lyons

Mol Cell· December 2020

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Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?
Anaïs Aulas, Pascal Finetti, Shawn M Lyons, François Bertucci, Daniel Birnbaum

Cancers (Basel)· September 2020

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Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation.
Nikita Fernandes, Luke Nero, Shawn M Lyons, Pavel Ivanov, Telsa M Mittelmeier

Biomolecules· September 2020

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eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function.
Shawn M Lyons, Prakash Kharel, Yasutoshi Akiyama, Sandeep Ojha, Dhwani Dave

Nucleic Acids Res· June 2020

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Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus.
Marco Mineo, Shawn M Lyons, Mykola Zdioruk, Niklas von Spreckelsen, Ruben Ferrer-Luna

Mol Cell· June 2020

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snoRNPs: Functions in Ribosome Biogenesis.
Sandeep Ojha, Sulochan Malla, Shawn M Lyons

Biomolecules· May 2020

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Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
David W Sanders, Nancy Kedersha, Daniel S W Lee, Amy R Strom, Victoria Drake, Shawn M Lyons

Cell· April 2020

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FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
Jean A Smith, Ennessa G Curry, R Eric Blue, Christine Roden, Samantha E R Dundon, Shawn M Lyons

J Cell Biol· April 2020

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