Publications by authors named "Sheila M Donnelly"

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Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.
Karine Thivierge, Sophie Cotton, Deborah A Schaefer, Michael W Riggs, Joyce To, Sheila M Donnelly

PLoS Negl Trop Dis· February 2014

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Aminopeptidases of malaria parasites: new targets for chemotherapy.
Katharine R Trenholme, Christopher L Brown, Tina S Skinner-Adams, Colin Stack, Jonathan Lowther, Sheila M Donnelly

Infect Disord Drug Targets· June 2010

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The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease.
Jonathan Lowther, Mark W Robinson, Sheila M Donnelly, Weibo Xu, Colin M Stack

PLoS Negl Trop Dis· March 2010

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An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host.
Mark W Robinson, Ranjeeta Menon, Sheila M Donnelly, John P Dalton, Shoba Ranganathan

Mol Cell Proteomics· August 2009

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The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.
Selma Maric, Sheila M Donnelly, Mark W Robinson, Tina Skinner-Adams, Katharine R Trenholme

Biochemistry· June 2009

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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.
Sheena McGowan, Corrine J Porter, Jonathan Lowther, Colin M Stack, Sarah J Golding, Sheila M Donnelly

Proc Natl Acad Sci U S A· February 2009

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Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors.
Mark W Robinson, Jose F Tort, Jonathan Lowther, Sheila M Donnelly, Emily Wong

Mol Cell Proteomics· June 2008

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Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.
Colin M Stack, Conor R Caffrey, Sheila M Donnelly, Amritha Seshaadri, Jonathan Lowther

J Biol Chem· April 2008

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Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica.
Mary Sekiya, Grace Mulcahy, Jane A Irwin, Colin M Stack, Sheila M Donnelly

FEBS Lett· September 2006

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Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum.
Elaine McCarthy, Colin Stack, Sheila M Donnelly, Sean Doyle, Victoria H Mann

Int J Parasitol· May 2004

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Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines.
John P Dalton, Sandra O Neill, Colin Stack, Peter Collins, Alan Walshe, Sheila M Donnelly

Int J Parasitol· September 2003

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