Publications by authors named "Shengna Han"

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HNF4A-AS1 promotes hepatic steatosis in metabolic dysfunction-associated steatotic liver disease by driving HNF4A degradation.
Mengyao Yan, Xiaofei Wang, Xiaoyang Hou, Zijing Wang, Yanjiao Qiu, Shengna Han, Lirong Zhang

Drug Metab Dispos· December 2025

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Lactylation in Cardiovascular Diseases: Current Progress and Perspectives.
Zhi-Mo Wang, Qing-Wen Yu, Cong Wang, Shu-Hui Wang, Pei Wang, Li-Rong Zhang, Sheng-Na Han

J Am Heart Assoc· October 2025

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METTL3 regulates rifampicin-induced CYP3A4 expression by activating PXR translation and nuclear import and stabilizing CYP3A4 mRNA.
Jingya Wang, Yihang Yu, Zaihuan Xiong, Pei Wang, Zijing Wang, Shengna Han, Lirong Zhang

Biochem Pharmacol· September 2025

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DSG3 promotes bladder cancer growth and metastasis via AKT/GSK3β/β-catenin pathway.
Tao Wang, Anqi Du, Yuan Peng, Jianjian Yin, Guoqiang Sun, Yihang Yu, Zhangran Sun, Qi Chang, Shengna Han, Lirong Zhang

J Transl Med· July 2025

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ALKBH5 promotes cardiac fibroblasts pyroptosis after myocardial infarction through Notch1/NLRP3 pathway.
Liu-Gen Cui, Shu-Hui Wang, Sumra Komal, Jian-Jian Yin, Miao-Miao Zhai, Li-Rong Zhang, Sheng-Na Han

Cell Signal· March 2025

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Role of HNF4A-AS1/HNRNPC-mediated HNF4A ubiquitination protection against ritonavir-induced hepatotoxicity.
Xiaofei Wang, Zijing Wang, Jingya Wang, Yihang Yu, Yiting Wang, Shengna Han, Lirong Zhang

Mol Pharmacol· March 2025

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Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction.
Liu-Gen Cui, Miao-Miao Zhai, Jian-Jian Yin, Zhi-Mo Wang, Shu-Hui Wang, Li-Rong Zhang, Sheng-Na Han

Eur J Pharmacol· February 2025

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Epigenetic Regulation in Myocardial Fibroblasts and Its Impact on Cardiovascular Diseases.
Sumra Komal, Yuan Gao, Zhi-Mo Wang, Qing-Wen Yu, Pei Wang, Li-Rong Zhang, Sheng-Na Han

Pharmaceuticals (Basel)· October 2024

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Methyltransferase Like-3-Mediated N6-Methyladenosine Modification of Long Noncoding RNA Hepatocyte Nuclear Factor 1a Antisense RNA 1/Hepatocyte Nuclear Factor 4a Antisense RNA 1 Regulates Cytochrome P450 Enzyme Expression.
Yihang Yu, Jingya Wang, Zaihuan Xiong, Anqi Du, Xiaofei Wang, Shengna Han, Lirong Zhang

Drug Metab Dispos· September 2024

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The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
Yiting Wang, Pei Wang, Qi Wang, Shitong Chen, Xiaofei Wang, Shengna Han, Lirong Zhang

Biochem Pharmacol· February 2024

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An association study of with levofloxacin-induced severe cutaneous adverse drug reactions in Han Chinese.
Menglin Jiang, Jin Yang, Linlin Yang, Lina Wang, Ting Wang, Shengna Han, Lirong Zhang, Jin Zhang, Zhen Zhang

iScience· August 2023

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inhibitors as a potential treatment strategy in heart failure-inferences from gene expression profiling.
Sumra Komal, Atia Gohar, Saad Althobaiti, Ishtiaq Ahmad Khan, Liu-Gen Cui, Li-Rong Zhang, Sheng-Na Han

Front Cardiovasc Med· July 2023

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Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications.
Hanhan Zhu, Guangming Liu, Qi Chang, Mengyao Yan, Kun Yang, Shengna Han, Lirong Zhang

Toxics· January 2023

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Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3β/caspase-1.
Shu-Hui Wang, Meng-Jin Sun, Si-Yue Ding, Chun-Li Liu, Jing-Min Wang, Sheng-Na Han

Front Cardiovasc Med· January 2023

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Epigenetic Regulation of Macrophage Polarization in Cardiovascular Diseases.
Sumra Komal, Sheng-Na Han, Liu-Gen Cui, Miao-Miao Zhai, Yue-Jiao Zhou, Li-Rong Zhang

Pharmaceuticals (Basel)· January 2023

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Association of sleep duration with risk of type 2 diabetes mellitus in a rural Chinese population: a nested case-control study.
Songyang Cui, Yuqian Li, Yu Chen, Pengfei Ren, Mengying Fan, Lulu Zhang, Shengna Han

Sleep Breath· December 2022

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GSK3β mediates the spatiotemporal dynamics of NLRP3 inflammasome activation.
Suyavaran Arumugam, Yanqin Qin, Ziwen Liang, Sheng-Na Han, S L Tejaswi Boodapati

Cell Death Differ· October 2022

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Potential therapeutic strategies for myocardial infarction: the role of Toll-like receptors.
Sumra Komal, Nimrah Komal, Ali Mujtaba, Shu-Hui Wang, Li-Rong Zhang, Sheng-Na Han

Immunol Res· October 2022

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The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway.
Xue-Ling Su, Shu-Hui Wang, Sumra Komal, Liu-Gen Cui, Rui-Cong Ni, Li-Rong Zhang, Sheng-Na Han

Acta Pharmacol Sin· September 2022

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Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy.
Weidong Li, Chenxv Xing, Limeng Bao, Shengna Han, Tianxia Luo

BMC Genomics· August 2022

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GSK-3β-mediated activation of NLRP3 inflammasome leads to pyroptosis and apoptosis of rat cardiomyocytes and fibroblasts.
Shu-Hui Wang, Liu-Gen Cui, Xue-Ling Su, Sumra Komal, Rui-Cong Ni, Li-Rong Zhang, Sheng-Na Han

Eur J Pharmacol· April 2022

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Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
Cheng Chang, Shu-Hui Wang, Li-Na Xu, Xue-Ling Su, Yi-Fan Zeng, Li-Rong Zhang, Sheng-Na Han

J Interv Card Electrophysiol· March 2022

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Correction to: Glycogen synthase kinase 3 beta inhibitor SB216763 improves Kir2.1 expression after myocardia infraction in rats.
Cheng Chang, Shu-Hui Wang, Li-Na Xu, Xue-Ling Su, Yi-Fan Zeng, Li-Rong Zhang, Sheng-Na Han

J Interv Card Electrophysiol· March 2022

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Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Li-Na Xu, Shu-Hui Wang, Xue-Ling Su, Sumra Komal, Hong-Kun Fan, Li-Rong Zhang, Sheng-Na Han

Front Pharmacol· July 2021

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The Long Noncoding RNA Hepatocyte Nuclear Factor 4 Antisense RNA 1 Negatively Regulates Cytochrome P450 Enzymes in Huh7 Cells via Histone Modifications.
Pei Wang, Shitong Chen, Yiting Wang, Xiaofei Wang, Liang Yan, Shengna Han, Lirong Zhang

Drug Metab Dispos· May 2021

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