Publications by authors named "Sherry Shu"

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Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice.
Sherry T Shu, Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E Smithgall

Sci Rep· January 2025

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Nef defect attenuates HIV viremia and immune dysregulation in the bone marrow-liver-thymus-spleen (BLTS) humanized mouse model.
Shivkumar Biradar, Yash Agarwal, Antu Das, Sherry T Shu, Jasmine Samal

Virology· October 2024

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PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication.
Lori A Emert-Sedlak, Colin M Tice, Haibin Shi, John J Alvarado, Sherry T Shu

Cell Chem Biol· April 2024

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Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission.
Chandra N Roy, Sherry T Shu, Christopher Kline, Lora Rigatti, Thomas E Smithgall

Sci Rep· October 2023

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PROTAC-mediated Degradation of HIV-1 Nef Efficiently Restores Cell-surface CD4 and MHC-I Expression and Blocks HIV-1 Replication.
Lori A Emert-Sedlak, Colin M Tice, Haibin Shi, John J Alvarado, Sherry T Shu

bioRxiv· September 2023

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Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.
Lori A Emert-Sedlak, Haibin Shi, Colin M Tice, Li Chen, John J Alvarado, Sherry T Shu

Viruses· September 2022

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Visualization of Host Cell Kinase Activation by Viral Proteins Using GFP Fluorescence Complementation and Immunofluorescence Microscopy.
Sherry T Shu, Wing Fai Li, Thomas E Smithgall

Bio Protoc· July 2021

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Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes.
Ryan P Staudt, John J Alvarado, Lori A Emert-Sedlak, Haibin Shi, Sherry T Shu

J Biol Chem· October 2020

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HIV-1 Nef dimers short-circuit immune receptor signaling by activating Tec-family kinases at the host cell membrane.
Wing Fai Li, Manish Aryal, Sherry T Shu, Thomas E Smithgall

J Biol Chem· April 2020

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Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors.
Nicole A Kohart, Said M Elshafae, Aylin A Demirer, Wessel P Dirksen, Justin T Breitbach, Sherry T Shu

Leuk Lymphoma· February 2020

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Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo.
Mark C Weir, Sherry T Shu, Ravi K Patel, Sabine Hellwig, Li Chen

ACS Chem Biol· June 2018

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Cell-based Fluorescence Complementation Reveals a Role for HIV-1 Nef Protein Dimerization in AP-2 Adaptor Recruitment and CD4 Co-receptor Down-regulation.
Sherry T Shu, Lori A Emert-Sedlak, Thomas E Smithgall

J Biol Chem· February 2017

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Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists.
Lori A Emert-Sedlak, H Marie Loughran, Haibin Shi, John L Kulp, Sherry T Shu

Bioorg Med Chem Lett· March 2016

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Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity.
Lori A Emert-Sedlak, Purushottam Narute, Sherry T Shu, Jerrod A Poe, Haibin Shi

Chem Biol· January 2013

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Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.
Chelsea K Martin, Wessel P Dirksen, Sherry T Shu, Jillian L Werbeck, Nanda K Thudi

Oral Oncol· June 2012

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Effects of parathyroid hormone-related protein and macrophage inflammatory protein-1α in Jurkat T-cells on tumor formation in vivo and expression of apoptosis regulatory genes in vitro.
Sherry T Shu, Wessel P Dirksen, Lisa G Lanigan, Chelsea K Martin, Nanda K Thudi

Leuk Lymphoma· April 2012

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HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck.
Teodora Pene-Dumitrescu, Sherry T Shu, Thomas E Wales, John J Alvarado, Haibin Shi

BMC Chem Biol· March 2012

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Development of a brain metastatic canine prostate cancer cell line.
Nanda K Thudi, Sherry T Shu, Chelsea K Martin, Lisa G Lanigan, Murali V P Nadella

Prostate· September 2011

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Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases.
Nanda K Thudi, Chelsea K Martin, Sridhar Murahari, Sherry T Shu, Lisa G Lanigan

Prostate· May 2011

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Induction of apoptosis by (-)-gossypol-enriched cottonseed oil in human breast cancer cells.
Weiping Ye, Hsiang-Lin Chang, Li-Shu Wang, Yi-Wen Huang, Sherry Shu

Int J Mol Med· July 2010

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The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice.
Ramiro E Toribio, Holly A Brown, Chad M Novince, Brandlyn Marlow, Krista Hernon, Sherry T Shu

FASEB J· June 2010

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Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells.
Sherry T Shu, Yasuro Sugimoto, Suling Liu, Hsiang-Lin Chang, Weiping Ye, Li-Shu Wang

Anticancer Res· June 2010

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Osteolytic bone resorption in adult T-cell leukemia/lymphoma.
Sherry T Shu, Chelsea K Martin, Nanda K Thudi, Wessel P Dirksen, Thomas J Rosol

Leuk Lymphoma· April 2010

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Interferon-gamma targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases.
Zhiqiang Xu, Michelle A Hurchla, Hongju Deng, Ozge Uluçkan, Fang Bu, Sherry Shu

J Biol Chem· February 2009

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Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation.
Murali V P Nadella, Sherry T Shu, Wessel P Dirksen, Nanda K Thudi, Kiran S Nadella

Retrovirology· June 2008

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