Publications by authors named "Shigehiro Ohdo"

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C-X-C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8 T cells within the tumor microenvironment.
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Shigehiro Ohdo

Int J Cancer· November 2025

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Feeding Time-Dependent Changes in the Preventive Effect of Empagliflozin on the Development of Peripheral Neuropathic Pain in Diabetic Model Mice.
Ai Sato, Naho Iwanaka, Tomoaki Yamauchi, Akito Tsuruta, Shigehiro Ohdo

Biol Pharm Bull· November 2025

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Discovery of a Selective Inhibitor of ZIP14 with Therapeutic Potential for Cancer-associated Cachexia.
Takafumi Hara, Gen Tanaka, Tomonori Tamura, Masaomi Terajima, Kengo Hamamura, Shigehiro Ohdo

bioRxiv· October 2025

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Response to Comment on "Proton Pump Inhibitor Concomitant Use to Prevent Oxaliplatin-Induced Peripheral Neuropathy: Clinical Retrospective Cohort Study".
Keisuke Mine, Takehiro Kawashiri, Yusuke Mori, Shunsuke Fujita, Mayako Uchida, Shigehiro Ohdo

Pharmacotherapy· September 2025

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Microcurrent stimulation induces cell death in p53-mutant and 5-FU-resistant breast cancer.
Tomohito Tanihara, Yuya Yoshida, Takashi Ogino, Yuma Terada, Fumiaki Tsurusaki, Shigehiro Ohdo

J Biol Chem· August 2025

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Proton pump inhibitor concomitant use to prevent oxaliplatin-induced peripheral neuropathy: Clinical retrospective cohort study.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Shigehiro Ohdo

Pharmacotherapy· July 2025

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N-acetyltransferase 10 promotes glioblastoma malignancy via mRNA stabilization of jumonji and AT-rich interaction domain containing 2.
Takuto Inoki, Akito Tsuruta, Yoshinori Masakado, Yuichiro Kai, Yuya Yoshida, Shigehiro Ohdo

J Biol Chem· June 2025

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Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment.
Rui Ji, Keijiro Ishikawa, Wei Tan, Kenichiro Mori, Ryotaro Tsukamoto, Shigehiro Ohdo

Invest Ophthalmol Vis Sci· June 2025

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The Circadian Clock Component REV-ERB Is an Analgesic Target for Cancer-Induced Tactile Pain Hypersensitivity.
Sai Yasukochi, Wakaba Yamakawa, Marie Taniguchi, Sayaka Itoyama, Akito Tsuruta, Shigehiro Ohdo

J Neurosci· May 2025

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Dopamine receptor D3 affects the expression of Period1 in mouse cells via DRD3-ERK-CREB signaling.
Masaki Matsuda, Takumi Nishi, Yuya Yoshida, Yuma Terada, Chihiro Matsuda-Hayama, Shigehiro Ohdo

Biochem Biophys Res Commun· March 2025

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Targeting macrophage circadian rhythms with microcurrent stimulation to activate cancer immunity through phagocytic defense.
Yuya Yoshida, Tomohito Tanihara, Keika Hamasaki, Fumiaki Tsurusaki, Taiki Fukuda, Shigehiro Ohdo

Theranostics· January 2025

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Monocyte/Macrophage-Specific Loss of ARNTL Suppresses Chronic Kidney Disease-Associated Cardiac Impairment.
Yuya Yoshida, Naoki Nishikawa, Kohei Fukuoka, Akito Tsuruta, Kaita Otsuki, Shigehiro Ohdo

Int J Mol Sci· December 2024

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Oncogenic accumulation of cysteine promotes cancer cell proliferation by regulating the translation of D-type cyclins.
Yumi Okano, Tomoaki Yamauchi, Runa Fukuzaki, Akito Tsuruta, Yuya Yoshida, Shigehiro Ohdo

J Biol Chem· November 2024

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RNA editing enzyme ADAR2 regulates P-glycoprotein expression in murine breast cancer cells through the circRNA-miRNA pathway.
Yuji Omata, Mai Haraguchi, Sae Yoshinaga, Takashi Ogino, Maseri Okawa, Shigehiro Ohdo

Biochem Biophys Res Commun· September 2024

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Hericenone C attenuates the second phase of formalin-induced nociceptive behavior by suppressing the accumulation of CD11c-positive cells in the paw epidermis via phosphorylated P65.
Junhao Li, Kengo Hamamura, Yuya Yoshida, Shimpei Kawano, Shohei Uchinomiya, Shigehiro Ohdo

Biochem Biophys Res Commun· August 2024

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Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT.
Tomoaki Yamauchi, Yumi Okano, Daishu Terada, Sai Yasukochi, Akito Tsuruta, Shigehiro Ohdo

Cancer Metab· August 2024

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Inhibition of G protein-coupled receptor 68 using homoharringtonine attenuates chronic kidney disease-associated cardiac impairment.
Yuya Yoshida, Kohei Fukuoka, Miyu Sakugawa, Masayuki Kurogi, Kengo Hamamura, Shigehiro Ohdo

Transl Res· July 2024

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Dosing Time-Dependent Difference in the Suppressive Effect of Empagliflozin on the Development of Mechanical Pain Hypersensitivity in Diabetic Mice.
Ai Sato, Sai Yasukochi, Naho Iwanaka, Tomoaki Yamauchi, Akito Tsuruta, Shigehiro Ohdo

J Pharmacol Exp Ther· July 2024

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The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity.
Takeshi Wakasa, Kentaro Nonaka, Akihito Harada, Yasuyuki Ohkawa, Chie Kikutake, Shigehiro Ohdo

Cell Death Discov· July 2024

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Circadian rhythms in CYP2A5 expression underlie the time-dependent effect of tegafur on breast cancer.
Yuya Yoshida, Taiki Fukuda, Tomohito Tanihara, Naoki Nishikawa, Serina Iwasa, Shigehiro Ohdo

Biochem Biophys Res Commun· May 2024

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Prostaglandin F2α Affects the Cycle of Clock Gene Expression and Mouse Behavior.
Yuya Tsurudome, Yuya Yoshida, Kengo Hamamura, Takashi Ogino, Sai Yasukochi, Shigehiro Ohdo

Int J Mol Sci· February 2024

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Time-Dependent Differences in Vancomycin Sensitivity of Macrophages Underlie Vancomycin-Induced Acute Kidney Injury.
Yuya Yoshida, Taiki Fukuda, Kohei Fukuoka, Toshitaka Nagayama, Tomohito Tanihara, Shigehiro Ohdo

J Pharmacol Exp Ther· January 2024

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Suppression of neuropathic pain in the circadian clock-deficient mice involves up-regulation of endocannabinoid system.
Wakaba Yamakawa, Sai Yasukochi, Yuya Tsurudome, Naoki Kusunose, Yuta Yamaguchi, Shigehiro Ohdo

PNAS Nexus· January 2024

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Implications of biological clocks in pharmacology and pharmacokinetics of antitumor drugs.
Shigehiro Ohdo, Satoru Koyanagi, Naoya Matsunaga

J Control Release· December 2023

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Modulation of cell physiology by bispecific nanobodies enabling changes in the intracellular localization of organelle proteins.
Akito Tsuruta, Daiki Kanetani, Yuki Shiiba, Takuto Inoki, Yuya Yoshida, Shigehiro Ohdo

Biochem Pharmacol· September 2023

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