Publications by authors named "Shilong You"

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Isolation and comprehensive characterization of bovine parvovirus 1 from diarrheic calves in Northeast China: Insights into evolution and biology.
Mingze Chen, Yingying Ma, Yue Yan, Xihuai Xue, Wei Wu, Shilong You

Virulence· December 2025

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Machine learning and multi-omics integration: advancing cardiovascular translational research and clinical practice.
Mingzhi Lin, Jiuqi Guo, Zhilin Gu, Wenyi Tang, Hongqian Tao, Shilong You

J Transl Med· April 2025

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E3 ubiquitin ligase WWP2 as a promising therapeutic target for diverse human diseases.
Shilong You, Jiaqi Xu, Yushan Guo, Xiaofan Guo, Ying Zhang

Mol Aspects Med· April 2024

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Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Zeyu Yin, Shilong You, Shu Zhang, Linlin Zhang, Boquan Wu

Biomed Pharmacother· October 2023

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α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Naijin Zhang, Ying Zhang, Jiaqi Xu, Pengbo Wang, Boquan Wu, Shilong You

Cell Res· September 2023

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Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
Shilong You, Jiaqi Xu, Zeyu Yin, Boquan Wu, Pengbo Wang

Cardiovasc Diabetol· May 2023

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BAF155 promotes cardiac hypertrophy and fibrosis through inhibition of WWP2-mediated PARP1 ubiquitination.
Naijin Zhang, Ying Zhang, Yong Chen, Hao Qian, Boquan Wu, Shilong You

Cell Discov· May 2023

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Deacetylation of Septin4 by SIRT2 (Silent Mating Type Information Regulation 2 Homolog-2) Mitigates Damaging of Hypertensive Nephropathy.
Ying Zhang, Naijin Zhang, Yuanming Zou, Chunyu Song, Kexin Cao, Shilong You

Circ Res· March 2023

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The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Xinxin Lu, Xinyue Huang, Haiqi Xu, Saien Lu, Shilong You

Cell Death Discov· October 2022

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The regulatory roles of the E3 ubiquitin ligase NEDD4 family in DNA damage response.
Xinxin Lu, Haiqi Xu, Jiaqi Xu, Saien Lu, Shilong You

Front Physiol· August 2022

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An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage.
Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Shilong You

Redox Biol· April 2022

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DNA Polymerase Gamma Recovers Mitochondrial Function and Inhibits Vascular Calcification by Interacted with p53.
Pengbo Wang, Boquan Wu, Shilong You, Saien Lu, Shengjun Xiong

Int J Biol Sci· March 2022

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E3 Ubiquitin ligase NEDD4 family‑regulatory network in cardiovascular disease.
Ying Zhang, Hao Qian, Boquan Wu, Shilong You, Shaojun Wu

Int J Biol Sci· November 2021

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Deacetylation-dependent regulation of PARP1 by SIRT2 dictates ubiquitination of PARP1 in oxidative stress-induced vascular injury.
Naijin Zhang, Ying Zhang, Boquan Wu, Shaojun Wu, Shilong You

Redox Biol· November 2021

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Comprehensive Bioinformatics Analysis Identifies as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
Shilong You, Jiaqi Xu, Boquan Wu, Shaojun Wu, Ying Zhang

Front Genet· August 2021

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The role of SIRT2 in vascular-related and heart-related diseases: A review.
Boquan Wu, Shilong You, Hao Qian, Shaojun Wu, Saien Lu

J Cell Mol Med· July 2021

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Septin4 promotes cardiomyocytes apoptosis by enhancing the VHL-mediated degradation of HIF-1α.
Shaojun Wu, Ying Zhang, Shilong You, Saien Lu, Naijin Zhang

Cell Death Discov· July 2021

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The Role of BRG1 in Antioxidant and Redox Signaling.
Shilong You, Ying Zhang, Jiaqi Xu, Hao Qian, Shaojun Wu

Oxid Med Cell Longev· May 2021

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Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Naijin Zhang, Ying Zhang, Shilong You, Yichen Tian, Saien Lu

Int J Biol Sci· February 2021

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The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis.
Fei Yi, Ying Zhang, Zhijun Wang, Zhuo Wang, Ziwei Li, Shilong You

Sci Adv· February 2021

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Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Jiaqi Xu, Ying Zhang, Shilong You, Yuxuan Guo, Shuang Chen

Life Sci· September 2020

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WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Ying Zhang, Shilong You, Yichen Tian, Saien Lu, Liu Cao

J Cell Mol Med· August 2020

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Structure and Function of HECT E3 Ubiquitin Ligases and their Role in Oxidative Stress.
Hao Qian, Ying Zhang, Boquan Wu, Shaojun Wu, Shilong You

J Transl Int Med· June 2020

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The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Hao Qian, Naijin Zhang, Boquan Wu, Shaojun Wu, Shilong You

J Cell Mol Med· April 2020

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Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Naijin Zhang, Ying Zhang, Boquan Wu, Shilong You, Yingxian Sun

Redox Biol· February 2020

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