Publications by authors named "Shingo Hotta"

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Bruton's tyrosine kinase is a possible therapeutic target in microscopic polyangiitis.
Issei Nakade, Yuto Tamura, Fuyu Hashimoto, Yuko Ariza, Shingo Hotta

Arthritis Res Ther· November 2023

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Investigation of the anti-tumor mechanism of tirabrutinib, a highly selective Bruton's tyrosine kinase inhibitor, by phosphoproteomics and transcriptomics.
Ryohei Kozaki, Tomoko Yasuhiro, Hikaru Kato, Jun Murai, Shingo Hotta

PLoS One· March 2023

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Overexpression of endogenous 1-deoxy-d-xylulose 5-phosphate synthase (DXS) in cyanobacterium Synechocystis sp. PCC6803 accelerates protein aggregation.
Kai Kudoh, Shingo Hotta, Midori Sekine, Rintaro Fujii, Arisu Uchida

J Biosci Bioeng· May 2017

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Anti-tumor efficacy study of the Bruton's tyrosine kinase (BTK) inhibitor, ONO/GS-4059, in combination with the glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab (GA101) demonstrates superior in vivo efficacy compared to ONO/GS-4059 in combination with rituximab.
Tomoko Yasuhiro, Wako Sawada, Christian Klein, Ryohei Kozaki, Shingo Hotta

Leuk Lymphoma· March 2017

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Prerequisite for highly efficient isoprenoid production by cyanobacteria discovered through the over-expression of 1-deoxy-d-xylulose 5-phosphate synthase and carbon allocation analysis.
Kai Kudoh, Yusuke Kawano, Shingo Hotta, Midori Sekine, Takafumi Watanabe

J Biosci Bioeng· July 2014

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Overactive bladder mediated by accelerated Ca2+ influx mode of Na+/Ca2+ exchanger in smooth muscle.
Hisao Yamamura, William C Cole, Satomi Kita, Shingo Hotta, Hidemichi Murata

Am J Physiol Cell Physiol· August 2013

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Cellular Ca2+ dynamics in urinary bladder smooth muscle from transgenic mice overexpressing Na+-Ca2+ exchanger.
Hidemichi Murata, Shingo Hotta, Eiji Sawada, Hisao Yamamura, Susumu Ohya

J Pharmacol Sci· October 2010

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Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle.
Shingo Hotta, Kozo Morimura, Susumu Ohya, Katsuhiko Muraki, Hiroshi Takeshima

J Physiol· July 2007

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Methyl-beta-cyclodextrin prevents Ca2+-induced Ca2+ release in smooth muscle cells of mouse urinary bladder.
Shingo Hotta, Hisao Yamamura, Susumu Ohya, Yuji Imaizumi

J Pharmacol Sci· January 2007

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Requirement of ryanodine receptors for pacemaker Ca2+ activity in ICC and HEK293 cells.
Masahiro Aoyama, Aki Yamada, Jing Wang, Susumu Ohya, Shinji Furuzono, Shingo Hotta

J Cell Sci· June 2004

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