Publications by authors named "Shion A Lim"

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High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19.
Anita E Qualls, Tasha Tsao, Irene Lui, Shion A Lim, Yapeng Su

JCI Insight· July 2025

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IL-27 elicits a cytotoxic CD8 T cell program to enforce tumour control.
Béatrice Bréart, Katherine Williams, Stellanie Krimm, Tiffany Wong, Brandon D Kayser, Shion A Lim

Nature· March 2025

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The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins.
Charlotte Nixon, Shion A Lim, Matt Sternke, Doug Barrick, Michael J Harms

Protein Sci· June 2024

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The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins.
Charlotte Nixon, Shion A Lim, Matt Sternke, Doug Barrick, Mike Harms

bioRxiv· July 2023

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CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease.
Ning Zhao, Shalini Chopra, Kai Trepka, Yung-Hua Wang, Sasank Sakhamuri, Shion A Lim

Clin Cancer Res· July 2022

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Engineering interferons and interleukins for cancer immunotherapy.
Patrick G Holder, Shion A Lim, Christine S Huang, Preeti Sharma, Yavuz S Dagdas

Adv Drug Deliv Rev· March 2022

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Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.
Shion A Lim, Jie Zhou, Alexander J Martinko, Yung-Hua Wang, Ekaterina V Filippova

J Clin Invest· February 2022

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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj, Shion A Lim

Nat Cell Biol· January 2022

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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj, Shion A Lim

bioRxiv· September 2021

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Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
Susanna K Elledge, Xin X Zhou, James R Byrnes, Alexander J Martinko, Irene Lui, Shion A Lim

Nat Biotechnol· August 2021

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Split enzymes: Design principles and strategy.
Shion A Lim, James A Wells

Methods Enzymol· June 2021

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Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2.
Shion A Lim, Josef A Gramespacher, Katarina Pance, Nicholas J Rettko, Paige Solomon

MAbs· March 2021

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Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
Colton J Bracken, Shion A Lim, Paige Solomon, Nicholas J Rettko, Duy P Nguyen

Nat Chem Biol· January 2021

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Exploring the Evolutionary History of Kinetic Stability in the α-Lytic Protease Family.
Charlotte F Nixon, Shion A Lim, Zachary R Sailer, Ivan N Zheludev, Christine L Gee

Biochemistry· January 2021

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Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Anum Glasgow, Jeff Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Shion A Lim

Proc Natl Acad Sci U S A· November 2020

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Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding.
James R Byrnes, Xin X Zhou, Irene Lui, Susanna K Elledge, Jeff E Glasgow, Shion A Lim

mSphere· September 2020

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Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
Anum Glasgow, Jeff Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Shion A Lim

bioRxiv· August 2020

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Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike.
Colton J Bracken, Shion A Lim, Paige Solomon, Nicholas J Rettko, Duy P Nguyen

bioRxiv· August 2020

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Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
Susanna K Elledge, Xin X Zhou, James R Byrnes, Alexander J Martinko, Irene Lui, Shion A Lim

medRxiv· August 2020

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Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.
Anna Moroz, Yung-Hua Wang, Jeremy M Sharib, Junnian Wei, Ning Zhao, Shion A Lim

Clin Cancer Res· July 2020

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A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding.
James R Byrnes, Xin X Zhou, Irene Lui, Susanna K Elledge, Jeff E Glasgow, Shion A Lim

medRxiv· May 2020

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Tracing a protein's folding pathway over evolutionary time using ancestral sequence reconstruction and hydrogen exchange.
Shion An Lim, Eric Richard Bolin, Susan Marqusee

Elife· September 2018

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The burst-phase folding intermediate of ribonuclease H changes conformation over evolutionary history.
Shion A Lim, Susan Marqusee

Biopolymers· August 2018

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Evolutionary trend toward kinetic stability in the folding trajectory of RNases H.
Shion A Lim, Kathryn M Hart, Michael J Harms, Susan Marqusee

Proc Natl Acad Sci U S A· November 2016

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The thermostability and specificity of ancient proteins.
Lucas C Wheeler, Shion A Lim, Susan Marqusee, Michael J Harms

Curr Opin Struct Biol· June 2016

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