Publications by authors named "Shixue Yang"

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LPC-engineered liposomes activate transcytosis for paclitaxel brain delivery and potentiation of TTFields/TMZ via TALECT regimen in glioblastoma.
Qi Zhan, Kaikai Yi, Shixue Yang, Biao Hong, Dongyuan Su

Theranostics· December 2025

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Endothelial cell-derived SDF-1α elicits stemness traits of glioblastoma dual-regulation of GLI1.
Ye Yuan, Xudong Liu, Liwen Kuang, Shixue Yang, Lihong Wang, Kaidi Yang

Theranostics· October 2025

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PEAKS activation by PROTAC EPIC-0726 potentiates temozolomide in glioblastoma via K63/K48 ubiquitination-dependent ERK/AKT suppression and p21 stabilization.
Biao Hong, Dongyuan Su, Xiaoteng Cui, Jixing Zhao, Qixue Wang, Eryan Yang, Shixue Yang

Neuro Oncol· October 2025

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Linagliptin synergizes with cPLA2 inhibition to enhance temozolomide efficacy by interrupting DPP4-mediated EGFR stabilization in glioma.
Dongyuan Su, Biao Hong, Shixue Yang, Jixing Zhao, Xiaoteng Cui, Eryan Yang

Acta Pharm Sin B· July 2025

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Modulation of gut microbiota in targeted cancer therapy: insights on the EGFR/VEGF/KRAS pathways.
Li Gong, Shixue Yang, Junli Huang, Yongsheng Li

Cancer Biol Med· November 2024

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HIF1α/ATF3 partake in PGK1 K191/K192 succinylation by modulating P4HA1/succinate signaling in glioblastoma.
Shixue Yang, Qi Zhan, Dongyuan Su, Xiaoteng Cui, Jixing Zhao, Eryan Yang

Neuro Oncol· August 2024

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CRISPR-Cas9 library screening combined with an exosome-targeted delivery system addresses tumorigenesis/TMZ resistance in the mesenchymal subtype of glioblastoma.
Jixing Zhao, Xiaoteng Cui, Qi Zhan, Kailiang Zhang, Dongyuan Su, Shixue Yang

Theranostics· May 2024

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EPIC-0628 abrogates HOTAIR/EZH2 interaction and enhances the temozolomide efficacy via promoting ATF3 expression and inhibiting DNA damage repair in glioblastoma.
Eryan Yang, Biao Hong, Yunfei Wang, Qixue Wang, Jixing Zhao, Shixue Yang

Cancer Lett· April 2024

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Deep-targeted gene sequencing reveals ARID1A mutation as an important driver of glioblastoma.
Menglin Xiao, Xiaoteng Cui, Can Xu, Lei Xin, Jixing Zhao, Shixue Yang

CNS Neurosci Ther· April 2024

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EPIC-1042 as a potent PTRF/Cavin1-caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for glioblastoma.
Biao Hong, Eryan Yang, Dongyuan Su, Jiasheng Ju, Xiaoteng Cui, Shixue Yang

Neuro Oncol· January 2024

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Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma.
Xiaoteng Cui, Jixing Zhao, Guanzhang Li, Chao Yang, Shixue Yang

Cancer Commun (Lond)· December 2023

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A novel compound EPIC-0412 reverses temozolomide resistance via inhibiting DNA repair/MGMT in glioblastoma.
Jixing Zhao, Shixue Yang, Xiaoteng Cui, Qixue Wang, Eryan Yang

Neuro Oncol· May 2023

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Blood exosomes-based targeted delivery of cPLA2 siRNA and metformin to modulate glioblastoma energy metabolism for tailoring personalized therapy.
Qi Zhan, Kaikai Yi, Xiaoteng Cui, Xueping Li, Shixue Yang

Neuro Oncol· November 2022

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TCA-phospholipid-glycolysis targeted triple therapy effectively suppresses ATP production and tumor growth in glioblastoma.
Shixue Yang, Jixing Zhao, Xiaoteng Cui, Qi Zhan, Kaikai Yi

Theranostics· October 2022

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Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Lijie Li, Qi Zhan, Kaikai Yi, Ning Chen, Xueping Li, Shixue Yang

J Mater Chem B· March 2022

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PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.
Kaikai Yi, Xiaoteng Cui, Xing Liu, Yunfei Wang, Jixing Zhao, Shixue Yang, Eryan Yang

Front Immunol· February 2022

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Endarterectomy versus stenting for the prevention of periprocedural stroke or death in patients with symptomatic or asymptomatic carotid stenosis: a meta-analysis of 10 randomized trials.
Wenqiang Xin, Shixue Yang, Qifeng Li, Xinyu Yang

Ann Transl Med· February 2021

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Risk factors involved in the formation of multiple intracranial aneurysms.
Wen-Qiang Xin, Peng-Ju Sun, Fan Li, Ming-Xun Cheng, Shi-Xue Yang, Xin-Yu Yang

Clin Neurol Neurosurg· November 2020

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