Publications by authors named "Shoko Hashimoto"

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Somatostatin-evoked Aβ catabolism in the brain: Mechanistic involvement of α-endosulfine-K channel pathway.
Naoto Watamura, Naomasa Kakiya, Per Nilsson, Satoshi Tsubuki, Naoko Kamano, Mika Takahashi, Shoko Hashimoto, Hiroki Sasaguri, Takashi Saito, Takaomi C Saido

Mol Psychiatry· March 2022

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Rod-shaped microglia represent a morphologically distinct subpopulation of disease-associated microglia.
Yukio Matsuba, Kenichi Nagata, Yosuke Kadota, Naruhiko Sahara, Takaomi C Saido, Shoko Hashimoto

J Neuroinflammation· July 2025

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The Role of Neprilysin and Insulin-Degrading Enzyme in the Etiology of Sporadic Alzheimer's Disease.
Takahiro Morito, Shoko Hashimoto, Risa Takamura, Naoto Watamura, Naomasa Kakiya

J Neurosci· June 2025

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In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds.
Naoto Watamura, Martha S Foiani, Sumi Bez, Mathieu Bourdenx, Alessia Santambrogio, Shoko Hashimoto

Nat Neurosci· February 2025

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Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab.
Nobuhisa Iwata, Satoshi Tsubuki, Misaki Sekiguchi, Kaori Watanabe-Iwata, Yukio Matsuba, Shoko Hashimoto

Life Sci Alliance· December 2024

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Tau Accumulation Induces Microglial State Alterations in Alzheimer's Disease Model Mice.
Kenichi Nagata, Shoko Hashimoto, Daisuke Joho, Ryo Fujioka, Yukio Matsuba

eNeuro· December 2024

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Neuronal glutathione depletion elevates the Aβ42/Aβ40 ratio and tau aggregation in Alzheimer's disease mice.
Khairun Nisa Binti Hashim, Yukio Matsuba, Mika Takahashi, Naoko Kamano, Ikuo Tooyama, Shoko Hashimoto

FEBS Lett· July 2024

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Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Naoko Kamano, Naoto Watamura

Sci Rep· January 2023

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Peritoneal natural killer cell chemotaxis is decreased in women with pelvic endometriosis.
Takashi Ushiwaka, Shinpei Yamamoto, Chika Yoshii, Shoko Hashimoto, Tamami Tsuzuki

Am J Reprod Immunol· September 2022

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Tau-binding protein PRMT8 facilitates vacuole degeneration in the brain.
Ayano Ishii, Yukio Matsuba, Naomi Mihira, Naoko Kamano, Takashi Saito, Shoko Hashimoto

J Biochem· September 2022

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An isogenic panel of knock-in mouse models: Profiling β-secretase inhibition and endosomal abnormalities.
Naoto Watamura, Kaori Sato, Gen Shiihashi, Ayami Iwasaki, Naoko Kamano, Shoko Hashimoto

Sci Adv· June 2022

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Early memory deficits and extensive brain network disorganization in the double knock-in mouse model of familial Alzheimer's disease.
Christopher Borcuk, Céline Héraud, Karine Herbeaux, Margot Diringer, Élodie Panzer, Shoko Hashimoto

Aging Brain· June 2022

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Recent Advances in the Modeling of Alzheimer's Disease.
Hiroki Sasaguri, Shoko Hashimoto, Naoto Watamura, Kaori Sato, Risa Takamura

Front Neurosci· March 2022

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Humanization of the entire murine gene provides a murine model of pathological human tau propagation.
Takashi Saito, Naomi Mihira, Yukio Matsuba, Hiroki Sasaguri, Shoko Hashimoto

J Biol Chem· August 2019

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Author Correction: Tau binding protein CAPON induces tau aggregation and neurodegeneration.
Shoko Hashimoto, Yukio Matsuba, Naoko Kamano, Naomi Mihira, Naruhiko Sahara

Nat Commun· July 2019

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Tau binding protein CAPON induces tau aggregation and neurodegeneration.
Shoko Hashimoto, Yukio Matsuba, Naoko Kamano, Naomi Mihira, Naruhiko Sahara

Nat Commun· June 2019

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Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells.
Keiro Shirotani, Yuma Hori, Ryohei Yoshizaki, Eri Higuchi, Marco Colonna, Shoko Hashimoto

Sci Rep· May 2019

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One-hour oral glucose tolerance test plasma glucose at gestational diabetes diagnosis is a common predictor of the need for insulin therapy in pregnancy and postpartum impaired glucose tolerance.
Takeshi Nishikawa, Keiko Ono, Shoko Hashimoto, Hiroyuki Kinoshita, Takuro Watanabe

J Diabetes Investig· November 2018

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Protective effects of dietary kaempferol glycoside components from unripe soybean (Edamame, L. Merrill. 'Jindai') leaves and their serous metabolite on carbon tetrachloride-induced liver injury mice.
Yanqing Zang, Shoko Hashimoto, Changqing Yu, Kiharu Igarashi

J Food Sci Technol· November 2018

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Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID.
Hiroki Sasaguri, Kenichi Nagata, Misaki Sekiguchi, Ryo Fujioka, Yukio Matsuba, Shoko Hashimoto

Nat Commun· July 2018

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Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology.
Kenichi Nagata, Mika Takahashi, Yukio Matsuba, Fumi Okuyama-Uchimura, Kaori Sato, Shoko Hashimoto

Nat Commun· May 2018

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Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease.
Shoko Hashimoto, Takaomi C Saido

Open Biol· April 2018

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Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigm knockin paradigm.
Shoko Hashimoto, Ayano Ishii, Naoko Kamano, Naoto Watamura, Takashi Saito

J Biol Chem· March 2018

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APP mouse models for Alzheimer's disease preclinical studies.
Hiroki Sasaguri, Per Nilsson, Shoko Hashimoto, Kenichi Nagata, Takashi Saito

EMBO J· September 2017

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Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression.
Takashi Saito, Yukio Matsuba, Naomi Yamazaki, Shoko Hashimoto, Takaomi C Saido

J Neurosci· September 2016

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