Publications by authors named "Shomit Sengupta"

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Purine nucleotides are competitive inhibitors of apo-GOT1.
Narges Pourmandi, Arjun Jha, Kendall Muzzarelli, Hyunsu Lee, Zahra Assar, Shomit Sengupta

bioRxiv· September 2025

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Editorial Expression of Concern: p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.
Elsa R Flores, Kenneth Y Tsai, Denise Crowley, Shomit Sengupta, Annie Yang

Nature· March 2024

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Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.
Seong A Kang, David J O'Neill, Andreas W Machl, Casey J Lumpkin, Stephanie N Galda, Shomit Sengupta

Cell Chem Biol· September 2019

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Discovery of NV-5138, the first selective Brain mTORC1 activator.
Shomit Sengupta, Emilie Giaime, Sridhar Narayan, Seung Hahm, Jessica Howell

Sci Rep· March 2019

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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Ömer H Yilmaz, Pekka Katajisto, Dudley W Lamming, Yetis Gültekin, Khristian E Bauer-Rowe, Shomit Sengupta

Nature· June 2012

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Timothy R Peterson, Shomit S Sengupta, Thurl E Harris, Anne E Carmack, Seong A Kang

Cell· August 2011

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Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling.
Robert A Lindquist, Kathleen A Ottina, Douglas B Wheeler, Peggy P Hsu, Carson C Thoreen, Shomit Sengupta

Genome Res· March 2011

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mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.
Shomit Sengupta, Timothy R Peterson, Mathieu Laplante, Stephanie Oh, David M Sabatini

Nature· December 2010

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Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress.
Shomit Sengupta, Timothy R Peterson, David M Sabatini

Mol Cell· October 2010

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p63 and p73 transcriptionally regulate genes involved in DNA repair.
Yu-Li Lin, Shomit Sengupta, Katherine Gurdziel, George W Bell, Tyler Jacks

PLoS Genet· October 2009

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Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis.
David J Klumpp, Matthew T Rycyk, Michael C Chen, Praveen Thumbikat, Shomit Sengupta

Infect Immun· September 2006

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Dos D Sarbassov, Siraj M Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P Hsu

Mol Cell· April 2006

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Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family.
Elsa R Flores, Shomit Sengupta, John B Miller, Jamie J Newman, Roderick Bronson

Cancer Cell· April 2005

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Infectious response to E. coli: molecular and genetic pathways.
Anthony J Schaeffer, David J Klumpp, Adam C Weiser, Shomit Sengupta, Sarah G Forrestal

Int J Antimicrob Agents· September 2004

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Mast cell activation triggers a urothelial inflammatory response mediated by tumor necrosis factor-alpha.
Robert A Batler, Shomit Sengupta, Sarah G Forrestal, Anthony J Schaeffer, David J Klumpp

J Urol· August 2002

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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.
Elsa R Flores, Kenneth Y Tsai, Denise Crowley, Shomit Sengupta, Annie Yang

Nature· April 2002

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