Publications by authors named "Shoudeng Chen"

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Structural and functional bases of F. rodentium Cas9 provide insights into CRISPR-Cas protein engineering.
Mei Yang, Siqi Liu, Guanqiao Chen, Xi Liu, Dapeng Sun, Shoudeng Chen

Cell Genom· October 2025

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Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding.
Shaojie Xue, Suhua He, Zhaoxia Huang, Mei Yang, Guowei Hu, Xiaoxue Chen, Qiuyue Chen, Shoudeng Chen

Commun Biol· August 2025

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A spontaneous nonhuman primate model of inherited retinal degeneration.
Wei Yi, Mingming Xu, Ying Xue, Yingxue Cao, Ziqi Yang, Shoudeng Chen

JCI Insight· June 2025

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Corrigendum to "IgA class switching enhances neutralizing potency against SARS-CoV-2 by increased antibody hinge flexibility" [Antiv. Res. (2025) 106082].
Mengxin Xu, Zhaoyong Zhang, Yuzhu Sun, Haoting Mai, Siqi Liu, Shoudeng Chen, Yao-Qing Chen

Antiviral Res· May 2025

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IgA class switching enhances neutralizing potency against SARS-CoV-2 by increased antibody hinge flexibility.
Mengxin Xu, Zhaoyong Zhang, Yuzhu Sun, Haoting Mai, Siqi Liu, Shoudeng Chen, Yao-Qing Chen

Antiviral Res· March 2025

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Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung.
Tianchuan Zhu, Yuchen Xiao, Zhenxing Chen, Hanxi Ding, Shoudeng Chen

Nat Commun· January 2025

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Chromatin mimicry by human JC virus.
Uwe Schaefer, Yekaterina A Miroshnikova, Wei Xie, Adam G Larson, Ziyu Lu, Shoudeng Chen, Kexin Chen

bioRxiv· November 2024

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Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47.
Chunliu Huang, Xuefei Wang, Yingzhao Wang, Yongyi Feng, Xiumei Wang, Shan Chen, Chengzhou Mao, Shoudeng Chen, Jun Chen

Nat Cancer· March 2024

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DDX24 Mutation Alters NPM1 Phase Behavior and Disrupts Nucleolar Homeostasis in Vascular Malformations.
Haopei Zhang, Qiuyue Chen, Qianqian Zhang, Hairun Gan, Hanjie Li, Shoudeng Chen

Int J Biol Sci· September 2023

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Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential.
Jing Wang, Yuan-Fei Pan, Li-Fen Yang, Wei-Hong Yang, Kexin Lv, Wei-Chen Wu, Shoudeng Chen, Yao-Qing Chen

Nat Commun· July 2023

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Spike substitution T813S increases Sarbecovirus fusogenicity by enhancing the usage of TMPRSS2.
Yong Ma, Pengbin Li, Yunqi Hu, Tianyi Qiu, Lixiang Wang, Shifeng Chen, Jun Chen, Shoudeng Chen, Yao-Qing Chen

PLoS Pathog· May 2023

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A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.
Liang Wang, Chunling Wu, Wanling Peng, Ziliang Zhou, Jianzhi Zeng, Yefei Chen, Shoudeng Chen

Nat Commun· September 2022

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Color-Switchable Nanosilicon Fluorescent Probes.
Huai Chen, Jiang Xu, Yaping Wang, Da Wang, Raquel Ferrer-Espada, Shoudeng Chen

ACS Nano· September 2022

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A Bright, Nontoxic, and Non-aggregating red Fluorescent Protein for Long-Term Labeling of Fine Structures in Neurons.
Lin Ning, Yang Geng, Matthew Lovett-Barron, Xiaoman Niu, Mengying Deng, Shoudeng Chen

Front Cell Dev Biol· June 2022

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Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Xiaoxue Chen, Zhechong Zhou, Chunliu Huang, Ziliang Zhou, Sisi Kang, Qiuyue Chen, Jie Chen, Jun Chen, Shoudeng Chen

Front Immunol· January 2022

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FGF2 is overexpressed in asthma and promotes airway inflammation through the FGFR/MAPK/NF-κB pathway in airway epithelial cells.
Yuan-Yang Tan, Hui-Qin Zhou, Yu-Jing Lin, Liu-Tong Yi, Zhuang-Gui Chen, Shou-Deng Chen

Mil Med Res· January 2022

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Structural characteristics of coiled-coil regions in AF10-DOT1L and AF10-inhibitory peptide complex.
Zhechong Zhou, Sisi Kang, Zhaoxia Huang, Ziliang Zhou, Shoudeng Chen

J Leukoc Biol· December 2021

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Structural Basis of a Human Neutralizing Antibody Specific to the SARS-CoV-2 Spike Protein Receptor-Binding Domain.
Mei Yang, Jiaqi Li, Zhaoxia Huang, Heng Li, Yueming Wang, Xiaoxue Chen, Qiuyue Chen, Shoudeng Chen

Microbiol Spectr· October 2021

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A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation.
Sisi Kang, Mei Yang, Suhua He, Yueming Wang, Xiaoxue Chen, Yao-Qing Chen, Qiuyue Chen, Shoudeng Chen

Nat Commun· May 2021

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Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seq.
Bing He, Shuning Liu, Yuanyuan Wang, Mengxin Xu, Wei Cai, Shoudeng Chen, Yao-Qing Chen

Signal Transduct Target Ther· May 2021

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Reciprocating-flowing on-a-chip enables ultra-fast immunobinding for multiplexed rapid ELISA detection of SARS-CoV-2 antibody.
Yiren Liu, Yayin Tan, Quanying Fu, Maoren Lin, Jinxu He, Shoudeng Chen

Biosens Bioelectron· March 2021

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Structural characterization of cystathionine γ-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Yutong Wang, Huai Chen, Zhaoxia Huang, Mei Yang, Hailing Yu, Maochen Peng, Shoudeng Chen

Int J Biol Macromol· March 2021

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Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14 monocytes.
Ziliang Zhou, Chunliu Huang, Zhechong Zhou, Zhaoxia Huang, Lili Su, Xiaoxue Chen, Qiuyue Chen, Jun Chen, Shoudeng Chen

iScience· March 2021

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Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences.
Mei Yang, Suhua He, Xiaoxue Chen, Zhaoxia Huang, Ziliang Zhou, Qiuyue Chen, Shoudeng Chen

Front Chem· January 2021

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