Publications by authors named "Shresh Pathak"

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Corticosteroid-Resistant and Corticosteroid-Dependent AIED Patients Treated With Anakinra: A Decade of Experience.
Andrea Vambutas, Virginia Mullooly, Sharon Weber, Shresh Pathak

Otol Neurotol· October 2025

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A pilot study on the effect of SARS-CoV-2 spike protein on IL-1β-mediated inflammation in peripheral blood immune cells from AIED patients.
Shresh Pathak, Natalie Tan, Andrea Vambutas

Mol Med· May 2025

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Effect of betahistine on pro-inflammatory cytokine expression in autoimmune inner ear disease and Meniere's disease patients.
Ilana Yellin, Shresh Pathak, Andrea Vambutas

Laryngoscope Investig Otolaryngol· December 2024

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NaCl exposure results in increased expression and processing of IL-1β in Meniere's disease patients.
Shresh Pathak, Andrea Vambutas

Sci Rep· March 2022

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The Correlation of Clinical Corticosteroid Responsiveness With Expression of IL-6 in Peripheral Blood Immune Cells (PBMC) in Patients With Autoimmune Inner Ear Disease (AIED).
Scott W Gorthey, Shresh Pathak, Andrea Vambutas

Otol Neurotol· October 2021

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Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro.
Shresh Pathak, Andrea Vambutas

JCI Insight· February 2020

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The Balance of Tissue Inhibitor of Metalloproteinase-1 and Matrix Metalloproteinase-9 in the Autoimmune Inner Ear Disease Patients.
Logan Eisner, Andrea Vambutas, Shresh Pathak

J Interferon Cytokine Res· August 2017

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AAO: Autoimmune and Autoinflammatory (Disease) in Otology: What is New in Immune-Mediated Hearing Loss.
Andrea Vambutas, Shresh Pathak

Laryngoscope Investig Otolaryngol· October 2016

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N-Acetylcysteine attenuates tumor necrosis factor alpha levels in autoimmune inner ear disease patients.
Shresh Pathak, Corey Stern, Andrea Vambutas

Immunol Res· December 2015

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Corrigendum: Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages.
Sushil Kumar Pathak, Sanchita Basu, Kunal Kumar Basu, Anirban Banerjee, Shresh Pathak

Nat Immunol· March 2015

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Early efficacy trial of anakinra in corticosteroid-resistant autoimmune inner ear disease.
Andrea Vambutas, Martin Lesser, Virginia Mullooly, Shresh Pathak, Gerald Zahtz

J Clin Invest· September 2014

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Innate immune recognition of molds and homology to the inner ear protein, cochlin, in patients with autoimmune inner ear disease.
Shresh Pathak, Lynda J Hatam, Vincent Bonagura, Andrea Vambutas

J Clin Immunol· October 2013

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Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN.
Partab Rai, Andrei Plagov, Dileep Kumar, Shresh Pathak, Kamesh R Ayasolla

Exp Mol Pathol· February 2013

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Diagnostic and prognostic utility of measuring tumor necrosis factor in the peripheral circulation of patients with immune-mediated sensorineural hearing loss.
Maja Svrakic, Shresh Pathak, Eliot Goldofsky, Ronald Hoffman, Sujana S Chandrasekhar

Arch Otolaryngol Head Neck Surg· November 2012

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HIV gene expression deactivates redox-sensitive stress response program in mouse tubular cells both in vitro and in vivo.
Divya Salhan, Shresh Pathak, Mohammad Husain, Pranai Tandon, Dileep Kumar

Am J Physiol Renal Physiol· January 2012

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Ang II enhances tubular cell Ets-1 expression and associated down stream signaling is mediated through AT1 receptors.
Dileep Kumar, Liming Luan, Shresh Pathak, Divya Salhan, Sandeep Magoon

Ren Fail· February 2011

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IL-1β is overexpressed and aberrantly regulated in corticosteroid nonresponders with autoimmune inner ear disease.
Shresh Pathak, Elliot Goldofsky, Esther X Vivas, Vincent R Bonagura, Andrea Vambutas

J Immunol· February 2011

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Human immunodeficiency virus downregulates podocyte apoE expression.
Shitij Arora, Mohammad Husain, Dileep Kumar, Hitesh Patni, Shresh Pathak

Am J Physiol Renal Physiol· September 2009

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A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis.
Manikuntala Kundu, Sushil Kumar Pathak, Kuldeep Kumawat, Sanchita Basu, Gargi Chatterjee, Shresh Pathak

Nat Immunol· August 2009

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Helicobacter pylori protein HP0175 transactivates epidermal growth factor receptor through TLR4 in gastric epithelial cells.
Sanchita Basu, Sushil Kumar Pathak, Gargi Chatterjee, Shresh Pathak, Joyoti Basu

J Biol Chem· November 2008

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Mycobacterium avium-induced matrix metalloproteinase-9 expression occurs in a cyclooxygenase-2-dependent manner and involves phosphorylation- and acetylation-dependent chromatin modification.
Sanchita Basu, Shresh Pathak, Sushil Kumar Pathak, Asima Bhattacharyya, Anirban Banerjee

Cell Microbiol· December 2007

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Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages.
Sushil Kumar Pathak, Sanchita Basu, Kunal Kumar Basu, Anirban Banerjee, Shresh Pathak

Nat Immunol· June 2007

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Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha.
Sanchita Basu, Sushil Kumar Pathak, Anirban Banerjee, Shresh Pathak, Asima Bhattacharyya

J Biol Chem· January 2007

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TLR4-dependent NF-kappaB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages.
Sushil Kumar Pathak, Sanchita Basu, Asima Bhattacharyya, Shresh Pathak, Anirban Banerjee

J Immunol· December 2006

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Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages.
Sushil Kumar Pathak, Sanchita Basu, Asima Bhattacharyya, Shresh Pathak, Manikuntala Kundu

J Biol Chem· December 2005

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