Publications by authors named "Shu-ichi Hashimoto"

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Tri-specific tribodies targeting 5T4, CD3, and immune checkpoint drive stronger functional T-cell responses than combinations of antibody therapeutics.
Margherita Passariello, Lorenzo Manna, Rosa Rapuano Lembo, Asami Yoshioka, Toshikazu Inoue, Shu-Ichi Hashimoto

Cell Death Discov· February 2025

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Fast-tracking antibody maturation using a B cell-based display system.
Hitomi Masuda, Atsushi Sawada, Shu-Ichi Hashimoto, Kanako Tamai, Ke-Yi Lin

MAbs· December 2022

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Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo.
Margherita Passariello, Asami Yoshioka, Kota Takahashi, Shu-Ichi Hashimoto, Toshikazu Inoue

J Exp Clin Cancer Res· September 2022

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Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy.
Margherita Passariello, Asami Yoshioka, Kota Takahashi, Shu-Ichi Hashimoto, Rosa Rapuano Lembo

Int J Mol Sci· March 2022

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Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line.
Hidetaka Seo, Hitomi Masuda, Kenjiro Asagoshi, Tomoaki Uchiki, Shigehisa Kawata, Shu-Ichi Hashimoto

Cell Mol Immunol· June 2021

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Anti-Semaphorin 3A neutralization monoclonal antibody prevents sepsis development in lipopolysaccharide-treated mice.
Naoya Yamashita, Aoi Jitsuki-Takahashi, Miyuki Ogawara, Wataru Ohkubo, Tomomi Araki, Shu-ichi Hashimoto

Int Immunol· September 2015

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Influenza A whole virion vaccine induces a rapid reduction of peripheral blood leukocytes via interferon-α-dependent apoptosis.
Manabu Ato, Yoshimasa Takahashi, Hideki Fujii, Shu-ichi Hashimoto, Tomohiro Kaji

Vaccine· April 2013

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HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice.
Hideki Fujii, Manabu Ato, Yoshimasa Takahashi, Kaori Otake, Shu-Ichi Hashimoto

Int Immunol· July 2011

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Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40.
Waka Lin, Shu-Ichi Hashimoto, Hidetaka Seo, Takehiko Shibata, Kunihiro Ohta

Genes Cells· March 2008

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Modulation of immunoglobulin gene conversion in chicken DT40 by enhancing histone acetylation, and its application to antibody engineering.
Hidetaka Seo, Takatomi Yamada, Shu-ichi Hashimoto, Waka Lin, Kunihiro Ohta

Biotechnol Genet Eng Rev· January 2008

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An ex vivo method for rapid generation of monoclonal antibodies (ADLib system).
Hidetaka Seo, Shu-ichi Hashimoto, Kyoko Tsuchiya, Waka Lin, Takehiko Shibata

Nat Protoc· June 2007

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Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses.
Yasuko Tsunetsugu-Yokota, Manabu Ato, Yoshimasa Takahashi, Shu-ichi Hashimoto, Tomohiro Kaji

Jpn J Infect Dis· May 2007

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Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice.
Fumikiyo Nagawa, Natsuko Kishishita, Kazumichi Shimizu, Satoshi Hirose, Masato Miyoshi, Shu-ichi Hashimoto

Nat Immunol· February 2007

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Novel role of the Ras cascade in memory B cell response.
Yoshimasa Takahashi, Ayako Inamine, Shu-Ichi Hashimoto, Sachiko Haraguchi, Emi Yoshioka

Immunity· August 2005

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Immunological detection of severe acute respiratory syndrome coronavirus by monoclonal antibodies.
Kazuo Ohnishi, Masahiro Sakaguchi, Tomohiro Kaji, Kiyoko Akagawa, Tadayoshi Taniyama, Shu-ichi Hashimoto

Jpn J Infect Dis· April 2005

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A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicits systemic humoral immunity in mice.
Naomi Takasuka, Hideki Fujii, Yoshimasa Takahashi, Masataka Kasai, Shigeru Morikawa, Shu-ichi Hashimoto

Int Immunol· October 2004

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