Publications by authors named "Shu-yong Lin"

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Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma.
Wen-Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Shu-Yong Lin

Mol Oncol· August 2025

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Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Mengqi Li, Chen-Song Zhang, Yue Zong, Jin-Wei Feng, Teng Ma, Zhizhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· February 2025

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AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Shu-Yong Lin, Sheng-Cai Lin

Cell Res· October 2024

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Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Han-Ming Wu, Yang Vivian Yang, Na-Jun Huang, Li-Ping Fan, Ying-Ying Dai, Lin Liu, Shu-Yong Lin

Front Neurosci· April 2024

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Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Yu-Qing Wu, Chen-Song Zhang, Jinye Xiong, Dong-Qi Cai, Chen-Zhe Wang, Huiling Guo, Shu-Yong Lin, Sheng-Cai Lin

Cell Res· November 2023

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The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shu-Yong Lin, Sheng-Cai Lin

Nat Metab· October 2022

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Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Teng Ma, Xiao Tian, Baoding Zhang, Mengqi Li, Yu Wang, Shu-Yong Lin, Sheng-Cai Lin

Nature· March 2022

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AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Meng Shi, Xiao-Yu Huang, Xin-Yi Ren, Xiao-Yan Wei, Yue Ma, Zhi-Zhong Lin, Lintao Song, Shu-Yong Lin, Sheng-Cai Lin

Nat Cell Biol· March 2021

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SRC promotes lipogenesis: implications for obesity and breast cancer.
Shu-Yong Lin, Sheng-Cai Lin

Mol Cell Oncol· January 2021

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Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.
Lintao Song, Zhihua Liu, Hui-Hui Hu, Ying Yang, Terytty Yang Li, Zhi-Zhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Nat Commun· November 2020

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Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Mengqi Li, Chen-Song Zhang, Yue Zong, Jin-Wei Feng, Teng Ma, Zhizhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· September 2019

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Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress.
Yue Zong, Chen-Song Zhang, Mengqi Li, Wen Wang, Zhichao Wang, Shu-Yong Lin, Sheng-Cai Lin

Cell Res· June 2019

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Carbohydrates: Not All that Bad?
Shu-Yong Lin, Chen-Song Zhang, Sheng-Cai Lin

Cell Metab· November 2018

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Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury.
Yu Sun, Terytty Yang Li, Lintao Song, Cixiong Zhang, Jingyi Li, Zhi-Zhong Lin, Sheng-Cai Lin, Shu-Yong Lin

Hepatology· June 2018

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Reply.
Yu Sun, Shu-Yong Lin

Hepatology· June 2018

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Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.
Terytty Yang Li, Lintao Song, Yu Sun, Jingyi Li, Cong Yi, Linkang Zhou, Shu-Yong Lin, Sheng-Cai Lin

Nat Commun· May 2018

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AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Hui Luo, Ming Jiang, Guili Lian, Qing Liu, Meng Shi, Lintao Song, Zhi-Zhong Lin, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· April 2018

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Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
Chen-Song Zhang, Simon A Hawley, Yue Zong, Mengqi Li, Zhichao Wang, Shu-Yong Lin, Sheng-Cai Lin

Nature· August 2017

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Metformin Activates AMPK through the Lysosomal Pathway.
Chen-Song Zhang, Mengqi Li, Teng Ma, Yue Zong, Jiwen Cui, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· October 2016

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C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis.
Qi Liu, Zhen Cheng, Lianzhong Luo, Yun Yang, Zhenzhu Zhang, Shu-Yong Lin

Oncotarget· June 2016

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ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Terytty Yang Li, Yu Sun, Yu Liang, Qing Liu, Yuzhe Shi, Lintao Song, Yan Lin, Shu-Yong Lin, Sheng-Cai Lin

Mol Cell· May 2016

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RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.
Chen-Song Zhang, Qi Liu, Mengqi Li, Shu-Yong Lin, Yongying Peng, Huiling Guo, Sheng-Cai Lin

Cell Res· September 2015

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Structure and mechanism of the unique C2 domain of Aida.
Li-Sha Zheng, Yi-Tong Liu, Lei Chen, Ying Wang, Yan-Ning Rui, Shu-Yong Lin, Sheng-Cai Lin

FEBS J· October 2014

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The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.
Chen-Song Zhang, Bin Jiang, Mengqi Li, Mingjiang Zhu, Yongying Peng, Ya-Lin Zhang, Huiling Guo, Shu-Yong Lin, Sheng-Cai Lin

Cell Metab· September 2014

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Mechanism and physiological significance of growth factor-related autophagy.
Terytty Yang Li, Shu-Yong Lin, Sheng-Cai Lin

Physiology (Bethesda)· November 2013

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