Publications by authors named "Shubha Murthy"

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Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells.
Shubha Murthy, Denise A Seabold, Lalit K Gautam, Adrian M Caceres, Rosemary Sease

Am J Physiol Lung Cell Mol Physiol· April 2025

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Targeting fibroblast-endothelial cell interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics.
Sinem Koc-Gunel, Emily C Liu, Lalit K Gautam, Ben A Calvert, Shubha Murthy

JCI Insight· February 2025

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Targeting Fibroblast-Endothelial Interactions in LAM Pathogenesis: 3D Spheroid and Spatial Transcriptomic Insights for Therapeutic Innovation.
Sinem Koc-Gunel, Emily C Liu, Lalit K Gautam, Ben A Calvert, Shubha Murthy

bioRxiv· September 2024

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Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem Cells.
Shubha Murthy, Denise A Seabold, Lalit K Gautam, Adrian M Caceres, Rosemary Sease

bioRxiv· September 2024

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TREM-1 is required for enhanced OpZ-induced superoxide generation following priming.
Shubha Murthy, Sankar Baruah, Jayden L Bowen, Kathy Keck, Brett A Wagner

J Leukoc Biol· September 2022

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TREM-1 regulates neutrophil chemotaxis by promoting NOX-dependent superoxide production.
Sankar Baruah, Shubha Murthy, Kathy Keck, Isabel Galvan, Allan Prichard

J Leukoc Biol· June 2019

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RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome.
Kevin T Urak, Giselle N Blanco, Shambhavi Shubham, Li-Hsien Lin, Justin P Dassie, Shubha Murthy

Nat Commun· January 2019

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Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity.
Shubha Murthy, Olha M Koval, Juan M Ramiro Diaz, Santosh Kumar, Daniel Nuno

PLoS One· November 2017

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Cu,Zn-Superoxide Dismutase-Mediated Redox Regulation of Jumonji Domain Containing 3 Modulates Macrophage Polarization and Pulmonary Fibrosis.
Chao He, Jennifer L Larson-Casey, Linlin Gu, Alan J Ryan, Shubha Murthy

Am J Respir Cell Mol Biol· July 2016

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CaMKII inhibition in type II pneumocytes protects from bleomycin-induced pulmonary fibrosis by preventing Ca2+-dependent apoptosis.
Christopher J Winters, Olha Koval, Shubha Murthy, Chantal Allamargot, Sara C Sebag

Am J Physiol Lung Cell Mol Physiol· January 2016

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Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis.
Heather L Osborn-Heaford, Shubha Murthy, Linlin Gu, Jennifer L Larson-Casey, Alan J Ryan

Free Radic Biol Med· September 2015

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Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure.
Shubha Murthy, Jennifer L Larson-Casey, Alan J Ryan, Chao He, Lester Kobzik

FASEB J· August 2015

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Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model.
Omar A Jaffer, A Brent Carter, Philip N Sanders, Megan E Dibbern, Christopher J Winters, Shubha Murthy

Am J Respir Cell Mol Biol· January 2015

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Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis.
Jennifer L Larson-Casey, Shubha Murthy, Alan J Ryan, A Brent Carter

J Biol Chem· December 2014

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Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages.
Chao He, Alan J Ryan, Shubha Murthy, A Brent Carter

J Biol Chem· July 2013

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SP-1 regulation of MMP-9 expression requires Ser586 in the PEST domain.
Shubha Murthy, Alan J Ryan, A Brent Carter

Biochem J· July 2012

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Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.
Heather L Osborn-Heaford, Alan J Ryan, Shubha Murthy, Ana-Monica Racila, Chao He

J Biol Chem· January 2012

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Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation.
Chao He, Shubha Murthy, Michael L McCormick, Douglas R Spitz, Alan J Ryan

J Biol Chem· April 2011

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Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1.
Shubha Murthy, Alan Ryan, Chao He, Rama K Mallampalli, A Brent Carter

J Biol Chem· August 2010

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Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis.
Shubha Murthy, Andrea Adamcakova-Dodd, Sarah S Perry, Linda A Tephly, Richard M Keller

Am J Physiol Lung Cell Mol Physiol· November 2009

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Regulation of fatty acid synthesis by farnesyl pyrophosphate.
Shubha Murthy, Huaxiang Tong, Raymond J Hohl

J Biol Chem· December 2005

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Liver-X-receptor-mediated increase in ATP-binding cassette transporter A1 expression is attenuated by fatty acids in CaCo-2 cells: effect on cholesterol efflux to high-density lipoprotein.
Shubha Murthy, Ella Born, Satya N Mathur, F Jeffrey Field

Biochem J· February 2004

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Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport.
F Jeffrey Field, Ella Born, Shubha Murthy, Satya N Mathur

Biochem J· December 2002

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LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells.
Shubha Murthy, Ella Born, Satya N Mathur, F Jeffrey Field

J Lipid Res· July 2002

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