Publications by authors named "Shui-Ping So"

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A novel single-chain enzyme complex with chain reaction properties rapidly producing thromboxane A and exhibiting powerful anti-bleeding functions.
Yan Li, Qun-Ying Li, Qing-Lan Ling, Shui-Ping So, Ke-He Ruan

J Cell Mol Med· December 2019

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Creating a mouse model resistant to induced ischemic stroke and cardiovascular damage.
Qing-Lan Ling, Anita J Mohite, Emma Murdoch, Hironari Akasaka, Qun-Ying Li, Shui-Ping So

Sci Rep· January 2018

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Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: Implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2.
Hironari Akasaka, Shui-Ping So, Ke-He Ruan

Biochemistry· June 2015

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Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.
Diana Ruan, Shui-Ping So

Life Sci· October 2014

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Resistant to thrombosis, induced stroke and heart arrest by incorporation of a single gene of PGI2-synthesizing COX-1-PGIS in vivo: Implication against human heart disease.
Ke-He Ruan, Anita J Mohite, Shui-Ping So

Int J Cardiol· October 2013

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Endothelial-like progenitor cells engineered to produce prostacyclin rescue monocrotaline-induced pulmonary arterial hypertension and provide right ventricle benefits.
Lei Zhou, Zhiqiang Chen, Peter Vanderslice, Shui-Ping So, Ke-He Ruan, James T Willerson

Circulation· August 2013

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Establishing novel prostacyclin-synthesizing cells with therapeutic potential against heart diseases.
Ke-He Ruan, Anita Mohite, Shui-Ping So, Cheng-Huai Ruan

Int J Cardiol· February 2013

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Screening and identification of dietary oils and unsaturated fatty acids in inhibiting inflammatory prostaglandin E2 signaling in fat stromal cells.
Diana Ruan, Shui-Ping So

BMC Complement Altern Med· August 2012

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Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells.
Qi Liu, Yutao Xi, Toya Terry, Shui-Ping So, Anita Mohite, James T Willerson

J Cell Physiol· July 2012

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A profile of NSAID-targeted arachidonic acid metabolisms in human embryonic stem cells (hESCs): implication of the negative effects of NSAIDs on heart tissue regeneration.
Annirudha Chillar, Shui-Ping So, Cheng-Huai Ruan, Harnath Shelat, Yong-Jian Geng

Int J Cardiol· August 2011

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Novel mechanism of the vascular protector prostacyclin: regulating microRNA expression.
Anita Mohite, Annirudha Chillar, Shui-Ping So, Vanessa Cervantes, Ke-He Ruan

Biochemistry· March 2011

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Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease.
Cheng-Huai Ruan, Shui-Ping So, Ke-He Ruan

Life Sci· January 2011

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Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2.
Ke-He Ruan, Vanessa Cervantes, Shui-Ping So

Protein Eng Des Sel· December 2009

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Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential.
Ke-He Ruan, Shui-Ping So, Hanjing Wu, Vanessa Cervantes

Arch Biochem Biophys· December 2008

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An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector.
Ke-He Ruan, Shui-Ping So, Vanessa Cervantes, Hanjing Wu, Cori Wijaya

FEBS J· December 2008

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Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis.
Annirudha Chillar, Jiaxin Wu, Shui-Ping So, Ke-He Ruan

FEBS Lett· August 2008

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A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor.
Feng Ni, Shui-Ping So, Vanessa Cervantes, Ke-He Ruan

FEBS J· January 2008

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Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin.
Ke-He Ruan, Hui Deng, Shui-Ping So

Biochemistry· November 2006

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The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase.
Ke-He Ruan, Hui Deng, Jiaxin Wu, Shui-Ping So

Arch Biochem Biophys· March 2005

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NMR structure of the thromboxane A2 receptor ligand recognition pocket.
Ke-He Ruan, Jiaxin Wu, Shui-Ping So, Lori A Jenkins, Cheng-Huai Ruan

Eur J Biochem· July 2004

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Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor.
Linda Geng, Jiaxin Wu, Shui-Ping So, Gangxiong Huang, Ke-He Ruan

Arch Biochem Biophys· March 2004

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Evidence of the residues involved in ligand recognition in the second extracellular loop of the prostacyclin receptor characterized by high resolution 2D NMR techniques.
Ke-He Ruan, Jiaxin Wu, Shui-Ping So, Lori A Jenkins

Arch Biochem Biophys· October 2003

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Solution structure of the third extracellular loop of human thromboxane A2 receptor.
Jiaxin Wu, Shui-Ping So, Ke-He Ruan

Arch Biochem Biophys· June 2003

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Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase.
Hui Deng, Jiaxin Wu, Shui-Ping So, Ke-He Ruan

Biochemistry· May 2003

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Determination of the membrane contact residues and solution structure of the helix F/G loop of prostaglandin I2 synthase.
Jiaxin Wu, Shui-Ping So, Ke-He Ruan

Arch Biochem Biophys· March 2003

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