Publications by authors named "Shuke Jia"

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IRF3 attenuates hypoxia signaling by retaining HIF-α in the cytoplasm.
Hongyan Deng, Shuke Jia, Chunchun Zhu, Jiale Hua, Zixuan Wang, Jian-Fang Gui

Cell Rep· January 2026

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Spring viremia of carp virus infection induces hypoxia response in zebrafish by stabilizing hif1α.
Zixuan Wang, Chunchun Zhu, Xueyi Sun, Hongyan Deng, Wen Liu, Shuke Jia

J Virol· January 2025

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Dual modifying of MAVS at lysine 7 by SIRT3-catalyzed deacetylation and SIRT5-catalyzed desuccinylation orchestrates antiviral innate immunity.
Xing Liu, Chunchun Zhu, Shuke Jia, Hongyan Deng, Jinhua Tang

Proc Natl Acad Sci U S A· April 2024

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Oxygen enhances antiviral innate immunity through maintenance of EGLN1-catalyzed proline hydroxylation of IRF3.
Xing Liu, Jinhua Tang, Zixuan Wang, Chunchun Zhu, Hongyan Deng, Shuke Jia, Sijia Fan, Jian-Fang Gui

Nat Commun· April 2024

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Deletion of prolyl hydroxylase domain-containing enzyme 3 (phd3) in zebrafish facilitates hypoxia tolerance.
Qian Liao, Hongyan Deng, Zixuan Wang, Guangqing Yu, Chunchun Zhu, Shuke Jia

J Biol Chem· December 2023

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Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance.
Qian Liao, Chunchun Zhu, Xueyi Sun, Zixuan Wang, Xiaoyun Chen, Shuke Jia

J Biol Chem· August 2023

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SET7 methylates the deubiquitinase OTUB1 at Lys to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis.
Hongyan Deng, Shuke Jia, Jinhua Tang, Fangjing Rong, Chenxi Xu

J Biol Chem· April 2023

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Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity.
Zixuan Wang, Xiaoyun Chen, Sijia Fan, Chunchun Zhu, Hongyan Deng, Shuke Jia

J Biol Chem· December 2022

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EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation.
Jinhua Tang, Hongyan Deng, Zixuan Wang, Huangyuan Zha, Qian Liao, Shuke Jia

J Biol Chem· June 2022

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OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation.
Xing Liu, Hongyan Deng, Jinhua Tang, Zixuan Wang, Chunchun Zhu, Shuke Jia

Cell Death Dis· June 2022

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Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage.
Xing Liu, Fangjing Rong, Jinhua Tang, Chunchun Zhu, Xiaoyun Chen, Shuke Jia

Cell Death Differ· April 2022

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