Publications by authors named "Shuwen Lei"

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A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy.
Guoping Li, Lingfei Sun, Cuiyan Xin, Tian Hao, Prakash Kharel, Shuwen Lei, Ji Lei

Science· August 2025

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Theabrownin remodels the circadian rhythm disorder of intestinal microbiota induced by a high-fat diet to alleviate obesity in mice.
Chunyan Zhao, Shuwen Lei, Hong Zhao, Zelin Li, Yue Miao

Food Funct· February 2025

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Quality characteristics and fibrous structure formation mechanism of walnut protein and wheat gluten meat analogues during high-moisture extrusion cooking process.
Shuwen Lei, Chunyan Zhao, Yue Miao, Hong Zhao, Zhichen Liu, Lei Zhao

Food Chem· January 2025

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Theabrownin from Pu-erh tea attenuated high-fat diet-induced metabolic syndrome in rat by regulating microRNA and affecting gut microbiota.
Bo Shan, Chunyan Zhao, Chunxiu Peng, Yue Miao, Shuwen Lei, Lei Zhao

Int J Biol Macromol· January 2025

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Synthesis and anti-proliferative effect of novel 4-Aryl-1, 3-Thiazole-TPP conjugates via mitochondrial uncoupling process.
Yixin Hu, Yang Zhang, Jie Guo, Shihao Chen, Jie Jin, Shuwen Lei, Lei Fu

Bioorg Chem· September 2024

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Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.
Lei Zhao, Chunyan Zhao, Yue Miao, Shuwen Lei, Yujing Li

Phytomedicine· September 2024

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Caffeine regulates both osteoclast and osteoblast differentiation via the AKT, NF-κB, and MAPK pathways.
Yue Miao, Lei Zhao, Shuwen Lei, Chunyan Zhao, Qiuping Wang

Front Pharmacol· June 2024

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Mitochondrial Respiration Inhibition Suppresses Papillary Thyroid Carcinoma PI3K/Akt/FoxO1/Cyclin D1 Pathway.
Bojie Chen, Shuwen Lei, Xinlu Yin, Mengjia Fei, Yixin Hu, Lei Fu

Front Oncol· July 2022

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Discovery of Sortase A covalent inhibitors with benzofuranene cyanide structures as potential antibacterial agents against Staphylococcus aureus.
Shuwen Lei, Yang Hu, Chang Yuan, Ran Sun, Juntao Wang, Lei Fu

Eur J Med Chem· February 2022

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One-Pot Enzymatic Synthesis and Biological Evaluation of Ganglioside GM3 Derivatives as Potential Cancer Immunotherapeutics.
Juntao Wang, Dan Lu, Ran Sun, Shuwen Lei, Shuhua Luo, Lei Fu

J Med Chem· February 2022

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Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice.
Jinxin Gu, Lixue Chen, Ran Sun, Jie-Li Wang, Juntao Wang, Shuwen Lei, Lei Fu

Front Mol Biosci· February 2022

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Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.
Sharmin Reza Chowdhury, Jinxin Gu, Yixin Hu, Juntao Wang, Shuwen Lei, Lei Fu

Eur J Med Chem· October 2021

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Interaction of tau with HNRNPA2B1 and N-methyladenosine RNA mediates the progression of tauopathy.
Lulu Jiang, Weiwei Lin, Cheng Zhang, Peter E A Ash, Mamta Verma, Shuwen Lei

Mol Cell· October 2021

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Design, synthesis and biological evaluation of novel thiazole-derivatives as mitochondrial targeting inhibitors of cancer cells.
Xin Dang, Shuwen Lei, Shuhua Luo, Yixin Hu, Juntao Wang, Lei Fu

Bioorg Chem· September 2021

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Biological evaluation of mitochondria targeting small molecules as potent anticancer drugs.
Shuhua Luo, Xin Dang, Juntao Wang, Chang Yuan, Yixin Hu, Shuwen Lei, Lei Fu

Bioorg Chem· September 2021

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Digital PCR for accurate quantification of pathogens: Principles, applications, challenges and future prospects.
Shuwen Lei, Song Chen, Qingping Zhong

Int J Biol Macromol· August 2021

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The pathophysiology of neurodegenerative disease: Disturbing the balance between phase separation and irreversible aggregation.
Chelsea J Webber, Shuwen Eric Lei, Benjamin Wolozin

Prog Mol Biol Transl Sci· June 2021

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TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.
Peter E A Ash, Shuwen Lei, Jenifer Shattuck, Samantha Boudeau, Yari Carlomagno

Proc Natl Acad Sci U S A· March 2021

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Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors.
Jian Shen, Xinxian Deng, Ran Sun, Mojdeh S Tavallaie, Juntao Wang, Shuwen Lei, Lei Fu

Eur J Med Chem· December 2020

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Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors.
Shuwen Lei, Dongdong Zhang, Yunyue Qi, Sharmin Reza Chowdhury, Ran Sun, Lei Fu

Eur J Med Chem· November 2020

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A 4-plex Droplet Digital PCR Method for Simultaneous Quantification and Differentiation of Pathogenic and Non-pathogenic Based on Single Intact Cells.
Shuwen Lei, Xiaokui Gu, Wei Xue, Zhangquan Rong, Zhe Wang

Front Microbiol· August 2020

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Drug discovery approaches targeting the incretin pathway.
Xinxian Deng, Mojdeh S Tavallaie, Ran Sun, Juntao Wang, Qingqing Cai, Shuwen Lei, Lei Fu

Bioorg Chem· June 2020

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Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology.
Peter E A Ash, Uma Dhawan, Samantha Boudeau, Shuwen Lei, Yari Carlomagno

Toxicol Sci· January 2019

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