Publications by authors named "Siel Olbrecht"

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Decoding tumor heterogeneity: A spatially informed pan-cancer analysis of the tumor microenvironment.
Francesca Lodi, Sam Vanmassenhove, Duojiao Chen, Bram Boeckx, Lucas Ferreira Maciel, Siel Olbrecht

Cell Rep Med· October 2025

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Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.
Dale Garsed, Tibor Zwimpfer, Sian Fereday, Ahwan Pandey, Dinuka Ariyaratne, Siel Olbrecht

Res Sq· October 2025

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Beyond deficiency: Clinical and molecular predictors of survival in patients with -deficient tubo-ovarian high-grade serous carcinoma.
Tibor A Zwimpfer, Sian Fereday, Ahwan Pandey, Dinuka Ariyaratne, Madawa W Jayawardana, Siel Olbrecht

medRxiv· September 2025

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PARP inhibitor predictive value of the Leuven HRD test compared with Myriad MyChoice CDx PLUS HRD on 468 ovarian cancer patients from the PAOLA-1/ENGOT-ov25 trial.
Liselore Loverix, Ignace Vergote, Pieter Busschaert, Adriaan Vanderstichele, Tom Venken, Siel Olbrecht

Eur J Cancer· July 2023

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CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.
Eun-Young Kang, Ashley Weir, Nicola S Meagher, Kyo Farrington, Gregg S Nelson, Siel Olbrecht

Cancer· March 2023

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Systematic study of tissue factor expression in solid tumors.
Johann S de Bono, Jeffrey R Harris, Saskia M Burm, Adriaan Vanderstichele, Mischa A Houtkamp, Siel Olbrecht

Cancer Rep (Hoboken)· February 2023

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Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk.
Eileen O Dareng, Jonathan P Tyrer, Daniel R Barnes, Michelle R Jones, Xin Yang, Siel Olbrecht

Eur J Hum Genet· May 2022

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MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.
Eun Young Kang, Joshua Millstein, Gordana Popovic, Nicola S Meagher, Adelyn Bolithon, Siel Olbrecht

Virchows Arch· April 2022

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Randomized CLIO/BGOG-ov10 trial of olaparib monotherapy versus physician's choice chemotherapy in relapsed ovarian cancer.
Adriaan Vanderstichele, Liselore Loverix, Pieter Busschaert, Els Van Nieuwenhuysen, Sileny N Han, Siel Olbrecht

Gynecol Oncol· April 2022

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Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer.
Adriaan Vanderstichele, Pieter Busschaert, Chiara Landolfo, Siel Olbrecht, An Coosemans

NPJ Genom Med· April 2022

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Polygenic risk modeling for prediction of epithelial ovarian cancer risk.
Eileen O Dareng, Jonathan P Tyrer, Daniel R Barnes, Michelle R Jones, Xin Yang, Siel Olbrecht

Eur J Hum Genet· March 2022

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High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification.
Siel Olbrecht, Pieter Busschaert, Junbin Qian, Adriaan Vanderstichele, Liselore Loverix

Genome Med· July 2021

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A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling.
Junbin Qian, Siel Olbrecht, Bram Boeckx, Hanne Vos, Damya Laoui

Cell Res· September 2020

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Prognostic Value of the Progesterone Receptor by Subtype in Patients with Estrogen Receptor-Positive, HER-2 Negative Breast Cancer.
Kathleen Van Asten, Laurence Slembrouck, Siel Olbrecht, Lynn Jongen, Olivier Brouckaert

Oncologist· February 2019

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Genomic signatures as predictive biomarkers of homologous recombination deficiency in ovarian cancer.
Adriaan Vanderstichele, Pieter Busschaert, Siel Olbrecht, Diether Lambrechts, Ignace Vergote

Eur J Cancer· November 2017

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