Publications by authors named "Signe Ingvarsen"

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The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1.
Kirstine S Nørregaard, Henrik J Jürgensen, Signe Z Ingvarsen, Signe S Heltberg, Christina E Hagensen

Matrix Biol· August 2022

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Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.
Signe Z Ingvarsen, Henrik Gårdsvoll, Sander van Putten, Kirstine S Nørregaard, Oliver Krigslund

Sci Rep· November 2020

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The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.
Christoffer Fagernæs Nielsen, Sander Maarten van Putten, Ida Katrine Lund, Maria Carlsén Melander, Kirstine Sandal Nørregaard, Signe Ziir Ingvarsen

Oncotarget· July 2017

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Xenotropic retrovirus Bxv1 in human pancreatic β cell lines.
Jeannette S Kirkegaard, Philippe Ravassard, Signe Ingvarsen, Marc Diedisheim, Emilie Bricout-Neveu

J Clin Invest· March 2016

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Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
Lars H Engelholm, Maria C Melander, Andreas Hald, Morten Persson, Daniel H Madsen, Signe Z Ingvarsen

J Pathol· January 2016

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Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.
Djoere Gaublomme, Tom Buyens, Lies De Groef, Michelle Stakenborg, Els Janssens, Signe Ingvarsen

J Neurochem· June 2014

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Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis.
Daniel H Madsen, Henrik J Jürgensen, Signe Ingvarsen, Maria C Melander, Reidar Albrechtsen

PLoS One· April 2014

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Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis.
Signe Ingvarsen, Astrid Porse, Charlotte Erpicum, Ludovic Maertens, Henrik J Jürgensen

J Biol Chem· April 2013

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Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo.
Ida K Lund, Morten G Rasch, Signe Ingvarsen, Jesper Pass, Daniel H Madsen

Front Pharmacol· October 2012

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Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.
Daniel H Madsen, Henrik J Jürgensen, Signe Ingvarsen, Maria C Melander, Ben Vainer

J Pathol· May 2012

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A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180.
Henrik J Jürgensen, Daniel H Madsen, Signe Ingvarsen, Maria C Melander, Henrik Gårdsvoll

J Biol Chem· September 2011

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The non-phagocytic route of collagen uptake: a distinct degradation pathway.
Daniel H Madsen, Signe Ingvarsen, Henrik J Jürgensen, Maria C Melander, Lars Kjøller

J Biol Chem· July 2011

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Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
Nami Sugiyama, Markku Varjosalo, Pipsa Meller, Jouko Lohi, Marko Hyytiäinen, Signe Ingvarsen

Cancer Res· October 2010

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MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.
Ludmila Szabova, Susan S Yamada, Helen Wimer, Kaliopi Chrysovergis, Signe Ingvarsen

J Bone Miner Res· November 2009

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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs.
R Grant Rowe, Xiao-Yan Li, Yuexian Hu, Thomas L Saunders, Ismo Virtanen, Signe Ingvarsen

J Cell Biol· February 2009

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The collagen receptor uPARAP/Endo180.
Lars H Engelholm, Signe Ingvarsen, Henrik J Jürgensen, Thore Hillig, Daniel H Madsen

Front Biosci (Landmark Ed)· January 2009

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Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.
Signe Ingvarsen, Daniel H Madsen, Thore Hillig, Leif R Lund, Kenn Holmbeck

Biol Chem· July 2008

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A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor.
Thore Hillig, Lars H Engelholm, Signe Ingvarsen, Daniel H Madsen, Henrik Gårdsvoll

J Biol Chem· May 2008

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Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.
Daniel H Madsen, Lars H Engelholm, Signe Ingvarsen, Thore Hillig, Rebecca A Wagenaar-Miller

J Biol Chem· September 2007

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