Publications by authors named "Signe Regner Michaelsen"

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Tumor and immune cell distribution in the tumor core and outer part of glioblastoma, IDH wildtype.
Vilde Pedersen, Arnon Møldrup Knudsen, Signe Regner Michaelsen, Rikke Hedegaard Dahlrot, Bjarne Winther Kristensen

J Neurooncol· December 2025

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Repeated responders to bevacizumab combination treatment in recurrent glioblastoma: a retrospective case study.
Maya Jeje Schuang Lü, Signe Regner Michaelsen, Alessio Locallo, Christina Schjellerup Eickhart-Dalbøge, David Scheie

J Neurooncol· November 2025

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Combined neocortical protein and morphological profiling of reactive microglia across Alzheimer's and Creutzfeldt-Jakob disease.
Vladyslav Vadymovych Tkach, Nicolai Schou Bager, Signe Regner Michaelsen, Thomas Litman, Knud Josefsen

Acta Neuropathol Commun· November 2025

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Expression of Glial Cell Line-derived Neurotrophic Factor and Its Receptors in Glioblastoma.
Jesper Dupont Ewald, Arnon Møldrup Knudsen, Helle Wohlleben, Lone Christiansen, Signe Regner Michaelsen

J Histochem Cytochem· October 2025

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Spatial transcriptomic analysis reveals lack of response to PD-1 blockade in recurrent glioblastoma.
Sara Blaabjerg Artzi, Marc Nihøj Klausen, Dylan Scott Lykke Harwood, Signe Regner Michaelsen, Simone Bendix Maarup

Acta Neuropathol· September 2025

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Using GeoMx DSP Spatial Proteomics to Investigate Immune Infiltration of NOD Mouse Islet and Exocrine Compartments.
Hasim Tekin, Claes Lindhardt, Julie Christine Antvorskov, Nicolai Schou Bager, Signe Regner Michaelsen

Mol Imaging Biol· December 2024

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Glioblastoma cells increase expression of notch signaling and synaptic genes within infiltrated brain tissue.
Dylan Scott Lykke Harwood, Vilde Pedersen, Nicolai Schou Bager, Ane Yde Schmidt, Tobias Overlund Stannius, Signe Regner Michaelsen

Nat Commun· September 2024

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Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas.
Stine Asferg Petterson, Mia Dahl Sørensen, Mark Burton, Mads Thomassen, Torben A Kruse, Signe Regner Michaelsen

Brain Pathol· January 2023

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Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors.
Arnon Møldrup Knudsen, Bo Halle, Oriane Cédile, Mark Burton, Christina Baun, Signe Regner Michaelsen

Neuro Oncol· July 2022

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A Prognostic Model for Glioblastoma Patients Treated With Standard Therapy Based on a Prospective Cohort of Consecutive Non-Selected Patients From a Single Institution.
Armita Armina Abedi, Kirsten Grunnet, Ib Jarle Christensen, Signe Regner Michaelsen, Aida Muhic

Front Oncol· February 2021

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Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma.
Thomas Urup, Linn Gillberg, Katja Kaastrup, Maya Jeje Schuang Lü, Signe Regner Michaelsen

Mol Oncol· May 2020

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Clinical Characteristics of Gliosarcoma and Outcomes From Standardized Treatment Relative to Conventional Glioblastoma.
Simone Frandsen, Helle Broholm, Vibeke Andrée Larsen, Kirsten Grunnet, Søren Møller, Signe Regner Michaelsen

Front Oncol· December 2019

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Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study.
Dorte Schou Nørøxe, Olga Østrup, Christina Westmose Yde, Lise Barlebo Ahlborn, Finn Cilius Nielsen, Signe Regner Michaelsen

Oncotarget· July 2019

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Extracranial metastases in glioblastoma-Two case stories.
Dorte Schou Nørøxe, Signe Regner Michaelsen, Helle Broholm, Søren Møller, Hans Skovgaard Poulsen

Clin Case Rep· February 2019

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Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival.
Signe Regner Michaelsen, Thomas Urup, Lars Rønn Olsen, Helle Broholm, Ulrik Lassen

J Neurooncol· May 2018

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Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B.
Mikkel Staberg, Rikke Darling Rasmussen, Signe Regner Michaelsen, Henriette Pedersen, Kamilla Ellermann Jensen

Mol Oncol· March 2018

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Biomarkers in Recurrent Grade III Glioma Patients Treated with Bevacizumab and Irinotecan.
Anders Toft, Thomas Urup, Ib Jarle Christensen, Signe Regner Michaelsen, Babloo Lukram

Cancer Invest· February 2018

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DNA Methylation Levels of the ELMO Gene Promoter CpG Islands in Human Glioblastomas.
Signe Regner Michaelsen, Derya Aslan, Thomas Urup, Hans Skovgaard Poulsen, Kirsten Grønbæk

Int J Mol Sci· February 2018

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Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients.
Thomas Urup, Line Mærsk Staunstrup, Signe Regner Michaelsen, Kristoffer Vitting-Seerup, Marc Bennedbæk

BMC Cancer· April 2017

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Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine.
Mikkel Staberg, Signe Regner Michaelsen, Rikke Darling Rasmussen, Mette Villingshøj, Hans Skovgaard Poulsen

Cell Oncol (Dordr)· February 2017

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Development and validation of a prognostic model for recurrent glioblastoma patients treated with bevacizumab and irinotecan.
Thomas Urup, Rikke Hedegaard Dahlrot, Kirsten Grunnet, Ib Jarle Christensen, Signe Regner Michaelsen

Acta Oncol· December 2016

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Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.
Thomas Urup, Signe Regner Michaelsen, Lars Rønn Olsen, Anders Toft, Ib Jarle Christensen

Mol Oncol· October 2016

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Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro.
Mikkel Staberg, Signe Regner Michaelsen, Louise Stobbe Olsen, Mette Kjølhede Nedergaard, Mette Villingshøj

Cancer Cell Int· April 2016

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Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma.
Mette Kjoelhede Nedergaard, Signe Regner Michaelsen, Lara Perryman, Janine Erler, Hans Skovgaard Poulsen

Nucl Med Biol· March 2016

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18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma.
Mette Kjoelhede Nedergaard, Signe Regner Michaelsen, Thomas Urup, Helle Broholm, Henrik El Ali

PLoS One· January 2016

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