Publications by authors named "Signe Tandrup Schmidt"

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Intraperitoneal administration of cationic liposomes containing a TLR3 agonist recruits type I conventional dendritic cells and primes a local CD8 T cell response.
Signe Tandrup Schmidt, Julie Zimmermann, Katharina Wørzner, Yvonne Perrie, Thomas Lindenstrøm

Vaccine· January 2026

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Microfluidic fabrication of pectin-coated liposomes for drug delivery.
Anitta Lutta, Qian Liu, Gabriel Kristian Pedersen, Mingdong Dong, Holger Grohganz, Signe Tandrup Schmidt

Drug Deliv Transl Res· September 2025

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Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection.
Katharina Wørzner, Signe Tandrup Schmidt, Julie Zimmermann, Ahmad Tami, Charlotta Polacek

EBioMedicine· March 2025

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Retinoic acid-adjuvanted vaccine induces antigen-specific secretory IgA in the gut of newborn piglets.
Gitte Erbs, Jeanne Toft Jakobsen, Signe Tandrup Schmidt, Dennis Christensen, Mick Bailey

Vaccine· February 2025

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Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route.
Melike Ongun, Abhijeet Girish Lokras, Saahil Baghel, Zhenning Shi, Signe Tandrup Schmidt

Eur J Pharm Biopharm· May 2024

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The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency.
Giulia Anderluzzi, Gustavo Lou, Stuart Woods, Signe Tandrup Schmidt, Simona Gallorini

J Control Release· February 2022

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A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease.
Julie Zimmermann, Signe Tandrup Schmidt, Ramona Trebbien, Rebecca Jane Cox, Fan Zhou

Int J Mol Sci· February 2022

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Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction.
Katharina Wørzner, Jóhanna Hvannastein, Signe Tandrup Schmidt, Camilla Foged, Ida Rosenkrands

Eur J Pharm Biopharm· August 2021

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Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses.
Giulia Anderluzzi, Signe Tandrup Schmidt, Robert Cunliffe, Stuart Woods, Craig W Roberts

J Control Release· February 2021

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Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice.
Katharina Wørzner, Daniel J Sheward, Signe Tandrup Schmidt, Leo Hanke, Julie Zimmermann

EBioMedicine· January 2021

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Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b.
Signe Tandrup Schmidt, Dennis Christensen, Yvonne Perrie

Pharmaceutics· December 2020

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Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection.
Gustavo Lou, Giulia Anderluzzi, Signe Tandrup Schmidt, Stuart Woods, Simona Gallorini

J Control Release· September 2020

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Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes.
Despo Chatzikleanthous, Signe Tandrup Schmidt, Giada Buffi, Ida Paciello, Robert Cunliffe

J Control Release· July 2020

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The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics.
Cameron Webb, Swapnil Khadke, Signe Tandrup Schmidt, Carla B Roces, Neil Forbes

Pharmaceutics· December 2019

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Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration.
Signe Tandrup Schmidt, Camilla Line Olsen, Henrik Franzyk, Katharina Wørzner, Karen Smith Korsholm

Eur J Pharm Biopharm· July 2019

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Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C).
Signe Tandrup Schmidt, Gabriel Kristian Pedersen, Malene Aaby Neustrup, Karen Smith Korsholm, Thomas Rades

Front Immunol· June 2019

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Rational Design and In Vivo Characterization of Vaccine Adjuvants.
Signe Tandrup Schmidt, Gabriel Kristian Pedersen, Dennis Christensen

ILAR J· December 2018

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Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein.
Letícia Rodrigues, Konstantinos N Raftopoulos, Signe Tandrup Schmidt, Fabian Schneider, Hendrik Dietz

J Control Release· September 2018

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Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder.
Aneesh Thakur, Pall Thor Ingvarsson, Signe Tandrup Schmidt, Fabrice Rose, Peter Andersen

Vaccine· May 2018

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Systematic Investigation of the Role of Surfactant Composition and Choice of oil: Design of a Nanoemulsion-Based Adjuvant Inducing Concomitant Humoral and CD4 T-Cell Responses.
Signe Tandrup Schmidt, Malene Aaby Neustrup, Stine Harloff-Helleberg, Karen Smith Korsholm, Thomas Rades

Pharm Res· August 2017

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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile.
Signe Tandrup Schmidt, Swapnil Khadke, Karen Smith Korsholm, Yvonne Perrie, Thomas Rades

J Control Release· October 2016

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Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators.
Signe Tandrup Schmidt, Camilla Foged, Karen Smith Korsholm, Thomas Rades, Dennis Christensen

Pharmaceutics· March 2016

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Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant.
Karen Smith Korsholm, Jon Hansen, Kasper Karlsen, Jonathan Filskov, Marianne Mikkelsen, Signe Tandrup Schmidt

Vaccine· June 2014

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Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01.
Pall Thor Ingvarsson, Signe Tandrup Schmidt, Dennis Christensen, Niels Bent Larsen, Wouter Leonardus Joseph Hinrichs

J Control Release· May 2013

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