Publications by authors named "Sigrid A Otto"

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Selective decline of intact HIV reservoirs during the first decade of ART followed by stabilization in memory T cell subsets.
Marieke M Nühn, Kobus Bosman, Terry Huisman, Wouter H A Staring, Lavina Gharu, Sigrid A Otto

AIDS· June 2025

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Turnover of Murine Cytomegalovirus-Expanded CD8 T Cells Is Similar to That of Memory Phenotype T Cells and Independent of the Magnitude of the Response.
Mariona Baliu-Piqué, Julia Drylewicz, Xiaoyan Zheng, Lisa Borkner, Arpit C Swain, Sigrid A Otto

J Immunol· February 2022

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Quantification of T-cell dynamics during latent cytomegalovirus infection in humans.
Sara P H van den Berg, Lyanne Y Derksen, Julia Drylewicz, Nening M Nanlohy, Lisa Beckers, Sigrid A Otto

PLoS Pathog· December 2021

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Cell-density independent increased lymphocyte production and loss rates post-autologous HSCT.
Mariona Baliu-Piqué, Vera van Hoeven, Julia Drylewicz, Lotte E van der Wagen, Anke Janssen, Sigrid A Otto

Elife· February 2021

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In vivo deuterium labelling in mice supports a dynamic model for memory T-cell maintenance in the bone marrow.
Mariona Baliu-Piqué, Sigrid A Otto, José A M Borghans, Kiki Tesselaar

Immunol Lett· June 2019

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The effect of switching protease inhibitors to raltegravir on endothelial function, in HIV-infected patients.
Maaike Krikke, Kiki Tesselaar, Guido E L van den Berk, Sigrid A Otto, Laura H Freriks

HIV Clin Trials· April 2018

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Maraviroc Intensification Improves Endothelial Function in Abacavir-Treated Patients, an Open-Label Randomized Cross-Over Pilot Study.
Maaike Krikke, Kiki Tesselaar, Joop E Arends, Julia Drylewicz, Sigrid A Otto

Infect Dis Ther· September 2016

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Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection.
Julia Drylewicz, Nienke Vrisekoop, Tendai Mugwagwa, Anne Bregje de Boer, Sigrid A Otto

PLoS One· August 2016

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Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial.
Steven F L van Lelyveld, Julia Drylewicz, Maaike Krikke, Ellen M Veel, Sigrid A Otto

PLoS One· May 2016

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Quantification of naive and memory T-cell turnover during HIV-1 infection.
Nienke Vrisekoop, Julia Drylewicz, Rogier Van Gent, Tendai Mugwagwa, Steven F L Van Lelyveld, Sigrid A Otto

AIDS· October 2015

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Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.
Ineke den Braber, Tendai Mugwagwa, Nienke Vrisekoop, Liset Westera, Ramona Mögling, Sigrid A Otto

Immunity· February 2012

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Long-term restoration of the human T-cell compartment after thymectomy during infancy: a role for thymic regeneration?
Rogier van Gent, Alvin W L Schadenberg, Sigrid A Otto, Rutger A J Nievelstein, Gertjan T Sieswerda

Blood· July 2011

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Decreased thymic output accounts for decreased naive T cell numbers in children with Down syndrome.
Beatrijs L P Bloemers, Louis Bont, Roel A de Weger, Sigrid A Otto, Jose A Borghans

J Immunol· April 2011

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Immune reconstitution in children following chemotherapy for haematological malignancies: a long-term follow-up.
Cornelis M van Tilburg, Rogier van Gent, Marc B Bierings, Sigrid A Otto, Elisabeth A M Sanders

Br J Haematol· January 2011

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In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow.
Rogier van Gent, Arnon P Kater, Sigrid A Otto, A Jaspers, José A M Borghans

Cancer Res· December 2008

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Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.
Nienke Vrisekoop, Rogier van Gent, Anne Bregje de Boer, Sigrid A Otto, Jan C C Borleffs

J Immunol· July 2008

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Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease.
Shailesh K Choudhary, Nienke Vrisekoop, Christine A Jansen, Sigrid A Otto, Hanneke Schuitemaker

J Virol· August 2007

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Early determinants of long-term T-cell reconstitution after hematopoietic stem cell transplantation for severe combined immunodeficiency.
José A Borghans, Robbert G Bredius, Mette D Hazenberg, Helene Roelofs, Els C Jol-van der Zijde, Sigrid A Otto

Blood· July 2006

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Short communication: No detrimental immunological effects of mycophenolate mofetil and HAART in treatment-naive acute and chronic HIV-1-infected patients.
Nienke Vrisekoop, Sanjay U C Sankatsing, Christine A Jansen, Marijke Th L Roos, Sigrid A Otto

AIDS Res Hum Retroviruses· December 2005

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Low-level CD4+ T cell activation is associated with low susceptibility to HIV-1 infection.
Fransje A Koning, Sigrid A Otto, Mette D Hazenberg, Linda Dekker, Maria Prins

J Immunol· November 2005

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Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1.
Mette D Hazenberg, Sigrid A Otto, Annemarie M C van Rossum, Henriëtte J Scherpbier, Ronald de Groot

Blood· December 2004

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Pre-seroconversion immune status predicts the rate of CD4 T cell decline following HIV infection.
Liselotte van Asten, Figen Danisman, Sigrid A Otto, José A M Borghans, Mette D Hazenberg

AIDS· September 2004

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Persistent immune activation in HIV-1 infection is associated with progression to AIDS.
Mette D Hazenberg, Sigrid A Otto, Birgit H B van Benthem, Marijke Th L Roos, Roel A Coutinho

AIDS· September 2003

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Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation.
Mette D Hazenberg, Sigrid A Otto, Dörte Hamann, Marijke Th L Roos, Hanneke Schuitemaker

AIDS· July 2003

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Early viral load and CD4+ T cell count, but not percentage of CCR5+ or CXCR4+ CD4+ T cells, are associated with R5-to-X4 HIV type 1 virus evolution.
Ronald P van Rij, Mette D Hazenberg, Birgit H B van Benthem, Sigrid A Otto, Maria Prins

AIDS Res Hum Retroviruses· May 2003

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