Publications by authors named "Sim-Leng Tien"

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Genetic landscape of uveal melanoma in Southeast Asia: high 1q gains and unique patterns of metastasis risk.
Chuanfei Chen, Mona Meng Wang, Alvin Soon Tiong Lim, Evelyn Yee Hsieh Heng, Sim Leng Tien

Eye Vis (Lond)· April 2025

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Real-world data on the use of emicizumab in patients with haemophilia A with and without inhibitors in Singapore.
Ming Wei Lee, May Anne Cheong, Heng Joo Ng, Sim Leng Tien, Joyce Ching Mei Lam

Ann Acad Med Singap· November 2023

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Development of inhibitors in women with mild haemophilia A and concurrent treatment with immune tolerance therapy and emicizumab.
May Anne Cheong, Jun Yang Ang, Shim Yen Yeam, Heng Joo Ng, Sim Leng Tien

Haemophilia· July 2023

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Validating lactate dehydrogenase (LDH) as a component of the PLASMIC predictive tool (PLASMIC-LDH).
Christopher Chin Keong Liam, Jim Yu-Hsiang Tiao, Yee Yee Yap, Yi Lin Lee, Jameela Sathar, Sim Leng Tien

Blood Res· March 2023

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Impact of the updated 2018 American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) guidelines on Human Epidermal Growth Factor Receptor 2 (HER2) gene testing in invasive breast cancers: A single center study.
Tse Hui Lim, Alvin Soon Tiong Lim, Sim Leng Tien, Puay Hoon Tan

Ann Diagn Pathol· June 2022

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Implementation of cytogenomic microarray with plasma cell enrichment enables better abnormality detection and risk stratification in patients with plasma cell neoplasia than conventional cytogenetics and fluorescence in situ hybridization.
Chuanfei Chen, Alvin Soon Tiong Lim, Lai Ching Lau, Tse Hui Lim, Evelyn Yee Hsieh Heng, Sim Leng Tien

Cancer Genet· April 2021

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Assessment of transient changes in oxygen diffusion of single red blood cells using a microfluidic analytical platform.
Kevin Ziyang Chng, Yan Cheng Ng, Bumseok Namgung, Justin Kok Soon Tan, Soyeon Park, Sim Leng Tien

Commun Biol· March 2021

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Chromosomal microarray analysis is superior in identifying cryptic aberrations in patients with acute lymphoblastic leukemia at diagnosis/relapse as a single assay.
Chuanfei Chen, Evelyn Yee Hsieh Heng, Alvin Soon Tiong Lim, Lai Ching Lau, Tse Hui Lim, Sim Leng Tien

Int J Lab Hematol· August 2019

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Symmetry recovery of cell-free layer after bifurcations of small arterioles in reduced flow conditions: effect of RBC aggregation.
Yan Cheng Ng, Bumseok Namgung, Sim Leng Tien, Hwa Liang Leo, Sangho Kim

Am J Physiol Heart Circ Physiol· August 2016

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Implications of the Updated 2013 American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations on Human Epidermal Growth Factor Receptor 2 Gene Testing Using Immunohistochemistry and Fluorescence In Situ Hybridization for Breast Cancer.
Tse Hui Lim, Alvin Soon Tiong Lim, Aye Aye Thike, Sim Leng Tien, Puay Hoon Tan

Arch Pathol Lab Med· February 2016

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CpG Oligonucleotide and Interleukin 2 stimulation enables higher cytogenetic abnormality detection rates than 12-o-tetradecanolyphorbol-13-acetate in Asian patients with B-cell chronic lymphocytic leukemia (B-CLL).
Fiona Pui San Liaw, Lai Ching Lau, Alvin Soon Tiong Lim, Tse Hui Lim, Geok Yee Lee, Sim Leng Tien

Int J Hematol· December 2014

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Amplification of 1q21 and other abnormalities in multiple myeloma patients from a tertiary hospital in singapore.
Alvin S T Lim, Sathish Krishnan, Tse Hui Lim, Karen See, Yit Jun Ng, Sim Leng Tien

Indian J Hematol Blood Transfus· December 2014

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Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore.
Alvin Soon Tiong Lim, Tse Hui Lim, Karen Hsu Shien See, Yit Jun Ng, Yu Min Tan, Sim Leng Tien

Chin Med J (Engl)· December 2013

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The road to memory: an early rest for the long journey.
Liam Pock Ho, Pui San Yit, Lee Hui Ng, Yeh Ching Linn, Yi Zhao, Sim Leng Tien

J Immunol· December 2013

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Differential outcomes in an extended family with constitutional t(11;22)(q23.3;q11.2).
Su Keyau Kee, Valene Hsu-Lin See, Patrick Chia, Wei Ching Tan, Sim Leng Tien

J Pediatr Genet· March 2013

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Cold agglutinin disease with prolymphocytic leukemia.
Richard Cheung Yiu, Sim-Leng Tien

Blood· May 2012

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HER2/neu revisited: quality and interpretive issues.
Syed Salahuddin Ahmed, Jabed Iqbal, Aye Aye Thike, Alvin Soon Tiong Lim, Tse Hui Lim, Sim Leng Tien

J Clin Pathol· February 2011

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Bone marrow cytogenetics workup: Application of lean management system to determine if additional cell workup is helpful and necessary to analysis.
Alvin S T Lim, Ting Jie Chen, Tse Hui Lim, Mary Tan, Lai Ching Lau, Sim Leng Tien

Ann Acad Med Singap· September 2010

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Synovial sarcoma of the kidney: a report of 4 cases with pathologic appraisal and differential diagnostic review.
Yia Swam Tan, Lay Guat Ng, Sidney Kam-Hung Yip, Miah-Hiang Tay, Alvin Soon-Tiong Lim, Sim Leng Tien

Anal Quant Cytol Histol· August 2010

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Occurrence of trisomy 12, t(14;18)(q32;q21), and t(8;14)(q24.1;q11.2) in a patient with B-cell chronic lymphocytic leukemia.
Lai-Ching Lau, Ping Lim, Yik-Chen Lim, Li-Min Teng, Tse-Hui Lim, Sim-Leng Tien

Cancer Genet Cytogenet· September 2008

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Holoprosencephaly: an antenatally-diagnosed case series and subject review.
Alvin S T Lim, Tse Hui Lim, Su Keyau Kee, Patrick Chia, Subramaniam Raman, Sim Leng Tien

Ann Acad Med Singap· July 2008

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Loss of the extra chromosome 21 in a patient with Down syndrome and myelodysplasia.
Daryl Tan, Lai Ching Lau, Li Min Teng, Swati Sane, Tse Hui Lim, Sim Leng Tien

Cancer Genet Cytogenet· January 2008

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Case report: induction of immune tolerance to factor VIII inhibitor after a major operation.
Liam-Pock Ho, Yoke-Kum Ho, Sim-Leng Tien

Ann Acad Med Singap· June 2007

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Trisomy 8 as sole cytogenetic abnormality in a case of chronic lymphocytic leukemia.
Lai-Ching Lau, Su-Keyau Kee, Sim-Leng Tien, Boon-Chai Koh Mickey

Cancer Genet Cytogenet· January 2007

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Dasatinib induces a response in malignant thymoma.
Charles Chuah, Tse Hui Lim, Alvin Soon Tiong Lim, Sim Leng Tien, Chong Hee Lim

J Clin Oncol· December 2006

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