Publications by authors named "Simmyung Yook"

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Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications.
Manju Shrestha, Yun-Seo Kil, Yunju Jo, Simmyung Yook, Ki Hyun Kim

Br J Pharmacol· January 2026

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Engineering Nanoparticles to Modulate Extracellular Matrix and Immune Components of the Tumor Microenvironment in Cancer Immunotherapy.
Bao-Toan Dang, Khang-Yen Pham, Ai-Han Nguyen, Jongjun Park, Taeg Kyu Kwon, Simmyung Yook

Biomater Res· December 2025

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Design of cathepsin-sensitive linkers for tumor-selective bioconjugate drug delivery.
Anil Giri, Yulim Shin, Jin Ha, Siyeon Chae, Prabhat Shrestha, Simmyung Yook

J Control Release· November 2025

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Surface-Engineering of Pancreatic Islets with Chitosan Microparticles to Inhibit IBMIR in Islet Xenotransplantation.
Manju Shrestha, Tiep Tien Nguyen, Junhyeung Park, Dinesh Chaudhary, Rabyya Kausar, Simmyung Yook

Small· September 2025

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Exploring therapeutic and diagnostic potential of cysteine cathepsin as targets for cancer therapy with nanomedicine.
Anil Giri, In-Sun Hong, Taeg Kyu Kwon, Jong-Sun Kang, Jee-Heon Jeong, Simmyung Yook

Int J Biol Macromol· June 2025

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Enhancing hair regrowth using rapamycin-primed mesenchymal stem cell-derived exosomes.
Manju Shrestha, Tiep Tien Nguyen, Rabyya Kausar, Dinesh Chaudhary, Ines Ferdiana Puspitasari, Simmyung Yook

Theranostics· June 2025

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CD44-targeted nanoparticles for remodeling the tumor microenvironment in a 3D macrophage-embedded ovarian cancer model with stem cell-like features.
Samjhana Shrestha, Anil Giri, Prabhat Shrestha, Seho Kweon, In-Sun Hong, Simmyung Yook

Int J Pharm· April 2025

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HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease.
Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Simmyung Yook

Redox Biol· February 2025

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Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer.
Thoa Thi Kim Nguyen, Seon Min Woo, Seung Un Seo, Asmita Banstola, Haesoo Kim, Simmyung Yook

Biomaterials· January 2025

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ROS-responsive thioketal nanoparticles delivering system for targeted ulcerative colitis therapy with potent HDAC6 inhibitor, tubastatin A.
Prabhat Shrestha, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jee-Heon Jeong, Simmyung Yook

Eur J Pharm Sci· October 2024

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Targeting tumor-associated macrophages with mannosylated nanotherapeutics delivering TLR7/8 agonist enhances cancer immunotherapy.
Bao-Toan Nguyen Dang, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jae-Hoon Chang, Simmyung Yook

J Control Release· August 2024

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Non-canonical deubiquitination of OTUB1 induces IFNγ-mediated cell cycle arrest via regulation of p27 stability.
Seul Gi Lee, Seon Min Woo, Seung Un Seo, Hyun Shik Lee, Sang Hyun Kim, Simmyung Yook

Oncogene· June 2024

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Endogenous stem cell mobilization and localized immunosuppression synergistically ameliorate DSS-induced Colitis in mice.
Shobha Regmi, Shiva Pathak, Dinesh Chaudhary, Jong Oh Kim, Joo-Won Nam, Simmyung Yook

Stem Cell Res Ther· June 2024

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Fabrication of stem cell heterospheroids with sustained-release chitosan and poly(lactic-co-glycolic acid) microspheres to guide cell fate toward chondrogenic differentiation.
Tiep Tien Nguyen, Yun-Seo Kil, Jong-Hyuk Sung, Yu Seok Youn, Ji Hoon Jeong, Simmyung Yook

Int J Biol Macromol· April 2024

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Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling.
Seul Gi Lee, Seon Min Woo, Seung Un Seo, Chan-Hyeong Lee, Moon-Chang Baek, Simmyung Yook

Exp Mol Med· February 2024

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Nanoparticle-based immunoengineering strategies for enhancing cancer immunotherapy.
Bao-Toan Nguyen Dang, Taeg Kyu Kwon, Sooyeun Lee, Jee-Heon Jeong, Simmyung Yook

J Control Release· January 2024

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Magnetic resonance imaging of pancreatic islets using tissue-adhesive particles containing iron oxide nanoparticles.
Phuong Le Tran, Tung Thanh Pham, Han Sin Lee, Soojung Hahn, Jeong Uk Choi, Simmyung Yook

J Control Release· December 2023

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Engineered therapeutic proteins for sustained-release drug delivery systems.
Thoa Thi Kim Nguyen, Khang-Yen Pham, Simmyung Yook

Acta Biomater· November 2023

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Reactive oxygen species-responsive dual-targeted nanosystem promoted immunogenic cell death against breast cancer.
Asmita Banstola, Mahesh Pandit, Ramesh Duwa, Jae-Hoon Chang, Jee-Heon Jeong, Simmyung Yook

Bioeng Transl Med· September 2023

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Dual receptor specific nanoparticles targeting EGFR and PD-L1 for enhanced delivery of docetaxel in cancer therapy.
Fakhrossadat Emami, Ramesh Duwa, Asmita Banstola, Seon Min Woo, Taeg Kyu Kwon, Simmyung Yook

Biomed Pharmacother· September 2023

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Tubeimoside-1 Enhances TRAIL-Induced Apoptotic Cell Death through STAMBPL1-Mediated c-FLIP Downregulation.
So Rae Song, Seung Un Seo, Seon Min Woo, Ji Yun Yoon, Simmyung Yook

Int J Mol Sci· July 2023

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Scalable and Uniform Fabrication of Dexamethasone-Eluting Depot-Engineered Stem Cell Spheroids as a Microtissue Construct to Target Bone Regeneration.
Tiep Tien Nguyen, Mai Thi Phuong, Manju Shrestha, Junhyeung Park, Pham Le Minh, Simmyung Yook

ACS Appl Mater Interfaces· June 2023

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T-cell engaging poly(lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer.
Ramesh Duwa, Ram Hari Pokhrel, Asmita Banstola, Mahesh Pandit, Prakash Shrestha, Simmyung Yook

Biomaterials· December 2022

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Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies.
Prabhat Shrestha, Nikita Katila, Sooyeun Lee, Ji Hae Seo, Jee-Heon Jeong, Simmyung Yook

Biomed Pharmacother· October 2022

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Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation.
Tiep Tien Nguyen, Duc-Vinh Pham, Junhyeung Park, Cao Dai Phung, Mahesh Raj Nepal, Simmyung Yook

Sci Adv· August 2022

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