Publications by authors named "Simon Coates"

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Concentration-QT modelling of the novel DHFR inhibitor P218 in healthy male volunteers.
Jӧrg Täubel, Ulrike Lorch, Georg Ferber, Christopher S Spencer, Anne Freier, Simon Coates

Br J Clin Pharmacol· January 2022

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First-in-human clinical trial to assess the safety, tolerability and pharmacokinetics of P218, a novel candidate for malaria chemoprotection.
M Farouk Chughlay, Emilie Rossignol, Cristina Donini, Myriam El Gaaloul, Ulrike Lorch, Simon Coates

Br J Clin Pharmacol· June 2020

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Time- and Race-Specific Haematological Reference Intervals for Healthy Volunteer Trials: A Retrospective Analysis of Pooled Data From Multiple Phase I Trials.
Simon Coates, Duolao Wang, Tomasz Pierscionek, Sara Fernandes, Dilshat Djumanov

Front Pharmacol· March 2020

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Efficient Design of Integrated and Adaptively Interlinked Protocols for Early-Phase Drug Development Programs.
Simon Coates, Oliver Pohl, Jean-Pierre Gotteland, Jörg Täubel, Ulrike Lorch

Ther Innov Regul Sci· January 2020

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Coadministration of the prostaglandin F2α receptor antagonist preterm labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone.
Oliver Pohl, Line Marchand, Jean-Pierre Gotteland, Simon Coates, Jörg Täubel

Br J Clin Pharmacol· July 2019

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Practical risk management in early phase clinical trials.
Simon Coates, Jörg Täubel, Ulrike Lorch

Eur J Clin Pharmacol· April 2019

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Confirmation of the Cardiac Safety of PGF Receptor Antagonist OBE022 in a First-in-Human Study in Healthy Subjects, Using Intensive ECG Assessments.
Jörg Täubel, Ulrike Lorch, Simon Coates, Sara Fernandes, Paul Foley

Clin Pharmacol Drug Dev· November 2018

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Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first-in-human trial in healthy postmenopausal women.
Oliver Pohl, Line Marchand, Jean-Pierre Gotteland, Simon Coates, Jörg Täubel

Br J Clin Pharmacol· August 2018

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What do metabolic rates tell us about thermal niches? Mechanisms driving crayfish distributions along an altitudinal gradient.
Rick J Stoffels, Adam J Richardson, Matthew T Vogel, Simon P Coates, Warren J Müller

Oecologia· January 2016

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