Publications by authors named "Simon Gaudreau"

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Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Marie-Edith Nepveu-Traversy, Malihe Hassanzadeh, Laurent Bruneau-Cossette, Élie Besserer-Offroy, Rebecca Brouillette, Simon Gaudreau

Nat Commun· December 2025

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Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial.
Bruno Maranda, Sébastien M Labbé, Magali Lurquin, Pascal Brabant, Alexandre Fugère, Simon Gaudreau

Lancet Infect Dis· January 2024

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Inhibition of PI3K/C/EBPβ axis in tolerogenic bone marrow-derived dendritic cells of NOD mice promotes Th17 differentiation and diabetes development.
Chantal Guindi, Farhan Ullah Khan, Alexandre Cloutier, Puregmaa Khongorzul, Ahmed Aziz Raki, Simon Gaudreau

Transl Res· May 2023

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Role of the p38 MAPK/C/EBPβ Pathway in the Regulation of Phenotype and IL-10 and IL-12 Production by Tolerogenic Bone Marrow-Derived Dendritic Cells.
Chantal Guindi, Alexandre Cloutier, Simon Gaudreau, Echarki Zerif, Patrick P McDonald

Cells· December 2018

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Constitutively active Stat5b signaling confers tolerogenic functions to dendritic cells of NOD mice and halts diabetes progression.
Echarki Zerif, Aida Maalem, Simon Gaudreau, Chantal Guindi, Muhammad Ramzan

J Autoimmun· January 2017

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Deregulation of protein phosphatase 2A and hyperphosphorylation of τ protein following onset of diabetes in NOD mice.
Marie-Amélie Papon, Noura B El Khoury, François Marcouiller, Carl Julien, Françoise Morin, Simon Gaudreau

Diabetes· February 2013

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Differential role of NF-κB, ERK1/2 and AP-1 in modulating the immunoregulatory functions of bone marrow-derived dendritic cells from NOD mice.
Chantal Guindi, Michaël Ménard, Alexandre Cloutier, Simon Gaudreau, Gilles Besin

Cell Immunol· April 2012

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Type I diabetes-associated tolerogenic properties of interleukin-2.
Aziz Alami Chentoufi, Simon Gaudreau, Alex Nguyen, Mahmoud Sabha, Abdelaziz Amrani

Clin Dev Immunol· October 2011

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IFN regulatory factors 4 and 8 expression in the NOD mouse.
Gilles Besin, Simon Gaudreau, Emilie Dumont-Blanchette, Michael Ménard, Chantal Guindi

Clin Dev Immunol· October 2011

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GM-CSF induces bone marrow precursors of NOD mice to skew into tolerogenic dendritic cells that protect against diabetes.
Simon Gaudreau, Chantal Guindi, Michaël Ménard, Ahmed Benabdallah, Gilles Dupuis

Cell Immunol· October 2010

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Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
Gilles Besin, Simon Gaudreau, Michaël Ménard, Chantal Guindi, Gilles Dupuis

Diabetes· August 2008

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Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
Simon Gaudreau, Chantal Guindi, Michaël Ménard, Gilles Besin, Gilles Dupuis

J Immunol· September 2007

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The serpin proteinase inhibitor 8: an endogenous furin inhibitor released from human platelets.
Julie Leblond, Marie-Hélène Laprise, Simon Gaudreau, Francine Grondin, Walter Kisiel

Thromb Haemost· February 2006

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