Publications by authors named "Simon Hirota"

Claim this Profile
I
Indole-3-propionic acid protects medium-diversity colitic mice via barrier enhancement preferentially over anti-inflammatory effects.
Kristoff M Nieves, Kyle L Flannigan, Elizabeth Hughes, Matthew Stephens, Andrew J Thorne, Simon A Hirota

Am J Physiol Gastrointest Liver Physiol· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Neuronal ALKAL2 and its ALK receptor contribute to the development of colitis-associated colorectal cancer.
Mélissa Delanne-Cuménal, Manon Defaye, Améline Delanne-Cuménal, Mansoor Ahmed, Valerie Ho, Simon Hirota

Proc Natl Acad Sci U S A· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
subspecies targets M cells in enteroid-derived monolayers through interactions with β1 integrins.
Grace Baruta, Kyle L Flannigan, Laurie Alston, Andrew Thorne, Hong Zhang, Simon A Hirota

Am J Physiol Gastrointest Liver Physiol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Early-life gut mycobiome core species modulate metabolic health in mice.
Mackenzie W Gutierrez, Erik van Tilburg Bernardes, Ellen Ren, Kristen N Kalbfleisch, Madeline Day, Simon A Hirota

Nat Commun· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Polynorepinephrine nanoparticles activate vascular smooth muscle alpha-1 adrenergic receptors.
Vinayaraj Ozhukil Kollath, Vivek Krishna Pulakazhi Venu, Mahmoud Saifeddine, Koichiro Mihara, Simon A Hirota

Nanoscale Adv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dietary Phytic Acid, Dephytinization, and Phytase Supplementation Alter Trace Element Bioavailability-A Narrative Review of Human Interventions.
Thiresia Chondrou, Nikoleta Adamidi, Dimosthenis Lygouras, Simon A Hirota, Odysseas Androutsos

Nutrients· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inflammasome activation links enteric Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release.
Xiao Han, Joannie M Allaire, Shauna M Crowley, Jocelyn J Chan, Kelly Lau, Simon A Hirota

Gut Microbes· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Challenges in IBD Research 2024: Preclinical Human IBD Mechanisms.
Matthew A Ciorba, Liza Konnikova, Simon A Hirota, Elena M Lucchetta, Jerrold R Turner

Inflamm Bowel Dis· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis.
Kyle L Flannigan, Kristoff M Nieves, Holly E Szczepanski, Alex Serra, Joshua W Lee, Simon A Hirota

Cell Mol Gastroenterol Hepatol· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New Concepts of the Interplay Between the Gut Microbiota and the Enteric Nervous System in the Control of Motility.
Fernando A Vicentini, Tanner Fahlman, Stephanie G Raptis, Laurie E Wallace, Simon A Hirota

Adv Exp Med Biol· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Protoporphyrin IX derived from dual-species anaerobic biofilms of and attenuates bovine neutrophil function.
Joey S Lockhart, Thibault Allain, Simon A Hirota, Andre G Buret, Douglas W Morck

Biofilm· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation-associated intestinal remodeling.
Holly E Szczepanski, Kyle L Flannigan, Barbara Mainoli, Laurie Alston, Grace M Baruta, Simon A Hirota

FASEB J· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation.
Fernando A Vicentini, Jake C Szamosi, Laura Rossi, Lateece Griffin, Kristoff Nieves, Simon A Hirota

Brain Behav Immun· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior.
Nina L Cluny, Kewir D Nyuyki, Wagdi Almishri, Lateece Griffin, Benjamin H Lee, Simon A Hirota

J Neuroinflammation· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Association of Circulating Fibrocytes With Fibrostenotic Small Bowel Crohn's Disease.
Aito Ueno, Humberto B Jijon, Richard Peng, Steven Sparksman, Barbara Mainoli, Simon Hirota

Inflamm Bowel Dis· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
X
Xenobiotic receptors and the regulation of intestinal homeostasis: harnessing the chemical output of the intestinal microbiota.
Kristoff M Nieves, Simon A Hirota, Kyle L Flannigan

Am J Physiol Gastrointest Liver Physiol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77).
Vivek Krishna Pulakazhi Venu, Mahmoud Saifeddine, Koichiro Mihara, Muniba Faiza, Evgueni Gorobets, Simon A Hirota

Mol Pharmacol· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor.
Fernando A Vicentini, Alexander J Mathews, Quentin J Pittman, Mark G Swain, Keith A Sharkey, Simon A Hirota

Brain Behav Immun· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.
Fernando A Vicentini, Catherine M Keenan, Laurie E Wallace, Crystal Woods, Jean-Baptiste Cavin, Simon A Hirota

Microbiome· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nr4A1 modulates inflammation-associated intestinal fibrosis and dampens fibrogenic signaling in myofibroblasts.
Vivek Krishna Pulakazhi Venu, Laurie Alston, Mircea Iftinca, Yi-Cheng Tsai, Matthew Stephens, Simon A Hirota

Am J Physiol Gastrointest Liver Physiol· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Colitis-Induced Microbial Perturbation Promotes Postinflammatory Visceral Hypersensitivity.
Nicolas Esquerre, Lilian Basso, Manon Defaye, Fernando A Vicentini, Nina Cluny, Simon A Hirota

Cell Mol Gastroenterol Hepatol· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gut microbiota profiles and fecal beta-glucuronidase activity in kidney transplant recipients with and without post-transplant diarrhea.
Lisa T Zhang, Lars F Westblade, Fatima Iqbal, Michael R Taylor, Alice Chung, Simon A Hirota

Clin Transplant· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Brain TNF drives post-inflammation depression-like behavior and persistent pain in experimental arthritis.
Fernando Lopes, Fernando A Vicentini, Nina L Cluny, Alexander J Mathews, Benjamin H Lee, Simon A Hirota

Brain Behav Immun· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the pregnane X receptor using microbial metabolite mimicry.
Zdeněk Dvořák, Felix Kopp, Cait M Costello, Jazmin S Kemp, Hao Li, Simon A Hirota

EMBO Mol Med· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteomics and Imaging in Crohn's Disease: TAILS of Unlikely Allies.
Barbara Mainoli, Simon Hirota, Laura E Edgington-Mitchell, Cathy Lu, Antoine Dufour

Trends Pharmacol Sci· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis