Publications by authors named "Simon Hufton"

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Development of an ELISA-Based Potency Assay for Inactivated Influenza Vaccines Using Cross-Reactive Nanobodies.
Chung Y Cheung, Sitara Dubey, Martina Hadrovic, Christina R Ball, Walter Ramage, Simon E Hufton

Vaccines (Basel)· September 2022

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Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Georgia Bullen, Jacob D Galson, Gareth Hall, Pedro Villar, Lien Moreels, Simon E Hufton

Front Immunol· July 2021

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Protection From Influenza by Intramuscular Gene Vector Delivery of a Broadly Neutralizing Nanobody Does Not Depend on Antibody Dependent Cellular Cytotoxicity.
Joanne Marie M Del Rosario, Matthew Smith, Kam Zaki, Paul Risley, Nigel Temperton, Simon E Hufton

Front Immunol· March 2021

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Maintaining 'standards' for biosimilar monoclonal antibodies.
Sandra Prior, Clive Metcalfe, Simon E Hufton, Meenu Wadhwa, Christian K Schneider

Nat Biotechnol· March 2021

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Broad Reactivity Single Domain Antibodies against Influenza Virus and Their Applications to Vaccine Potency Testing and Immunotherapy.
Andrew Tung Yep, Yasu Takeuchi, Othmar G Engelhardt, Simon E Hufton

Biomolecules· March 2021

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Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display.
Tiziano Gaiotto, Walter Ramage, Christina Ball, Paul Risley, George W Carnell, Simon E Hufton

Sci Rep· February 2021

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Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin.
Walter Ramage, Tiziano Gaiotto, Christina Ball, Paul Risley, George W Carnell, Simon E Hufton

Antibodies (Basel)· February 2019

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International standards for monoclonal antibodies to support pre- and post-marketing product consistency: Evaluation of a candidate international standard for the bioactivities of rituximab.
Sandra Prior, Simon E Hufton, Bernard Fox, Thomas Dougall, Peter Rigsby

MAbs· January 2018

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Surrogate CD16-expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies.
Shalom A Gurjar, Jeremy P Derrick, Rebecca J Dearman, Robin Thorpe, Simon Hufton

J Pharm Biomed Anal· September 2017

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Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning.
Tiziano Gaiotto, Simon E Hufton

PLoS One· May 2017

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The breadth of cross sub-type neutralisation activity of a single domain antibody to influenza hemagglutinin can be increased by antibody valency.
Simon E Hufton, Paul Risley, Christina R Ball, Diane Major, Othmar G Engelhardt

PLoS One· April 2015

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Antibody C region influences TGN1412-like functional activity in vitro.
Christina Ball, Bernard Fox, Simon Hufton, Giles Sharp, Stephen Poole

J Immunol· December 2012

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Affinity maturation and functional dissection of a humanised anti-RAGE monoclonal antibody by ribosome display.
Simon E Hufton

Methods Mol Biol· March 2012

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Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
William J Finlay, Orla Cunningham, Matthew A Lambert, Alfredo Darmanin-Sheehan, Xuemei Liu, Simon E Hufton

J Mol Biol· May 2009

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Identification and characterization of ErbB-3-binding protein-1 as a target for immunotherapy.
Saskia J A M Santegoets, Marco W J Schreurs, Anneke W Reurs, Jelle J Lindenberg, Esther W M Kueter, Simon E Hufton

J Immunol· August 2007

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Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.
René Michael Hoet, Edward H Cohen, Rachel Baribault Kent, Kristin Rookey, Sonia Schoonbroodt, Simon E Hufton

Nat Biotechnol· March 2005

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Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments.
Lydia Blaise, Anita Wehnert, Mieke P G Steukers, Twan van den Beucken, Hennie R Hoogenboom, Simon E Hufton

Gene· November 2004

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Affinity maturation of Fab antibody fragments by fluorescent-activated cell sorting of yeast-displayed libraries.
Twan van den Beucken, Henk Pieters, Mieke Steukers, Marcel van der Vaart, Robert Charles Ladner, Simon E Hufton

FEBS Lett· July 2003

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A panel of candidate tumor antigens in colorectal cancer revealed by the serological selection of a phage displayed cDNA expression library.
Veerle A Somers, Ricardo J Brandwijk, Ben Joosten, Peter T Moerkerk, Jan-Willem Arends, Simon E Hufton

J Immunol· September 2002

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Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer.
Judy R Van Beijnum, Peter T M Moerkerk, Andrea J Gerbers, Adriaan P De Bruïne, Jan-Willem Arends, Simon E Hufton

Int J Cancer· September 2002

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