Publications by authors named "Simon Langdon"

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The significance of molecular heterogeneity in breast cancer batch correction and dataset integration.
Nicholas Moir, Dominic A Pearce, Simon P Langdon, T Ian Simpson

Breast Cancer Res· December 2025

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FANCD2 expression affects platinum response and further characteristics of high grade serous ovarian cancer in cells with different genetic backgrounds.
Sarah J Taylor, Robert L Hollis, Charlie Gourley, C Simon Herrington, Simon P Langdon

Exp Mol Pathol· August 2024

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RFWD3 modulates response to platinum chemotherapy and promotes cancer associated phenotypes in high grade serous ovarian cancer.
Sarah J Taylor, Robert L Hollis, Charlie Gourley, C Simon Herrington, Simon P Langdon

Front Oncol· April 2024

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Variation in IL6ST cytokine family function and the potential of IL6 trans-signalling in ERα positive breast cancer cells.
Duniya Mosly, Kenneth MacLeod, Nicholas Moir, Arran Turnbull, Andrew H Sims, Simon P Langdon

Cell Signal· March 2023

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Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model.
Kate M Moore, Vera Cerqueira, Kenneth G MacLeod, Peter Mullen, Richard L Hayward, Simon P Langdon

Explor Target Antitumor Ther· February 2022

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Nuclear factor erythroid 2-related factor 2 modulates HER4 receptor in ovarian cancer cells to influence their sensitivity to tyrosine kinase inhibitors.
Ibrahim H Kankia, Poornima Paramasivan, Matthew Elcombe, Simon P Langdon, Yusuf Y Deeni

Explor Target Antitumor Ther· April 2021

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Estrogen Receptor Signaling in Cancer.
Simon P Langdon

Cancers (Basel)· September 2020

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Estrogen Signaling and Its Potential as a Target for Therapy in Ovarian Cancer.
Simon P Langdon, C Simon Herrington, Robert L Hollis, Charlie Gourley

Cancers (Basel)· June 2020

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Evaluation of Gene Expression Data From Cybrids and Tumours Highlights Elevated -Driven Proliferation in Triple-Negative Breast Cancer.
Akanksha Mishra, Maria Bonello, Adam Byron, Simon P Langdon, Andrew H Sims

Breast Cancer (Auckl)· June 2020

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The impact of tumour pH on cancer progression: strategies for clinical intervention.
Carol Ward, James Meehan, Mark E Gray, Alan F Murray, David J Argyle, Simon P Langdon

Explor Target Antitumor Ther· April 2020

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Precision Medicine and the Role of Biomarkers of Radiotherapy Response in Breast Cancer.
James Meehan, Mark Gray, Carlos Martínez-Pérez, Charlene Kay, Lisa Y Pang, Simon P Langdon

Front Oncol· April 2020

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Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer.
Sarah J Taylor, Mark J Arends, Simon P Langdon

Explor Target Antitumor Ther· February 2020

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Evaluation of the dual mTOR/PI3K inhibitors Gedatolisib (PF-05212384) and PF-04691502 against ovarian cancer xenograft models.
Simon P Langdon, Charlene Kay, In Hwa Um, Michael Dodds, Morwenna Muir

Sci Rep· December 2019

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Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.
Murat Bozdag, Marta Ferraroni, Carol Ward, Fabrizio Carta, Silvia Bua, Simon P Langdon

Eur J Med Chem· November 2019

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Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies.
Poornima Paramasivan, Ibrahim H Kankia, Simon P Langdon, Yusuf Y Deeni

Cancer Drug Resist· September 2019

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Biocompatibility of common implantable sensor materials in a tumor xenograft model.
Mark E Gray, James Meehan, Ewen O Blair, Carol Ward, Simon P Langdon

J Biomed Mater Res B Appl Biomater· July 2019

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Development and characterisation of acquired radioresistant breast cancer cell lines.
Mark Gray, Arran K Turnbull, Carol Ward, James Meehan, Carlos Martínez-Pérez, Simon P Langdon

Radiat Oncol· April 2019

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Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment.
Carol Ward, James Meehan, Mark Gray, Ian H Kunkler, Simon P Langdon

Curr Top Microbiol Immunol· March 2019

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HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer.
Edward J Jarman, Carol Ward, Arran K Turnbull, Carlos Martinez-Perez, James Meehan, Simon P Langdon

Breast Cancer Res· January 2019

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Human epidermal growth factor receptor targeted inhibitors for the treatment of ovarian cancer.
Maria Bonello, Andrew Harvey Sims, Simon Peter Langdon

Cancer Biol Med· November 2018

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NRF2 Regulates HER1 Signaling Pathway to Modulate the Sensitivity of Ovarian Cancer Cells to Lapatinib and Erlotinib.
Ibrahim H Kankia, Hilal S Khalil, Simon P Langdon, Peter R Moult, James L Bown

Oxid Med Cell Longev· August 2018

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Predictive markers of endocrine response in breast cancer.
Duniya Mosly, Arran Turnbull, Andrew Sims, Carol Ward, Simon Langdon

World J Exp Med· August 2018

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Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment.
Chrysi Xintaropoulou, Carol Ward, Alan Wise, Suzanna Queckborner, Arran Turnbull, Simon P Langdon

BMC Cancer· June 2018

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Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness.
Carol Ward, James Meehan, Mark Gray, Ian H Kunkler, Simon P Langdon

Metabolites· February 2018

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Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.
James Meehan, Carol Ward, Arran Turnbull, Jimi Bukowski-Wills, Andrew J Finch, Simon P Langdon

Oncotarget· June 2017

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