Publications by authors named "Simon M Bushell"

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Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Marie-Hélène Larraufie, Xiaolin Gao, Xiaobo Xia, Patrick J Devine, Joerg Kallen, Simon M Bushell

Cell Chem Biol· September 2021

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Rapid Evaluation of Small Molecule Cellular Target Engagement with a Luminescent Thermal Shift Assay.
Jonathan D Mortison, Ivan Cornella-Taracido, Gireedhar Venkatchalam, Anthony W Partridge, Nirodhini Siriwardana, Simon M Bushell

ACS Med Chem Lett· August 2021

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Systematic Chemogenetic Library Assembly.
Stephen M Canham, Yuan Wang, Allen Cornett, Douglas S Auld, Daniel K Baeschlin, Simon M Bushell

Cell Chem Biol· September 2020

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Discovery of a ZIP7 inhibitor from a Notch pathway screen.
Erin Nolin, Sara Gans, Luis Llamas, Somnath Bandyopadhyay, Scott M Brittain, Simon M Bushell

Nat Chem Biol· February 2019

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Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
Cheryl Carson, Pichai Raman, Jennifer Tullai, Lei Xu, Martin Henault, Simon M Bushell

PLoS One· May 2016

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Discovery of LFF571: an investigational agent for Clostridium difficile infection.
Matthew J LaMarche, Jennifer A Leeds, Adam Amaral, Jason T Brewer, Simon M Bushell

J Med Chem· March 2012

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Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids.
Matthew J LaMarche, Jennifer A Leeds, Kerri Amaral, Jason T Brewer, Simon M Bushell

J Med Chem· December 2011

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Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).
Aurelio Bonavia, Michael Franti, Erin Pusateri Keaney, Kelli Kuhen, Mohindra Seepersaud, Simon M Bushell

Proc Natl Acad Sci U S A· April 2011

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Progress toward a rationally designed, chemically powered rotary molecular motor.
T Ross Kelly, Xiaolu Cai, Fehmi Damkaci, Sreeletha B Panicker, Bin Tu, Simon M Bushell

J Am Chem Soc· January 2007

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Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
John W Huffman, Simon M Bushell, Sudhir N Joshi, Jenny L Wiley, Billy R Martin

Bioorg Med Chem· January 2006

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Total synthesis of nigellicine and nigeglanine hydrobromide.
Eric L Elliott, Simon M Bushell, Marta Cavero, Brian Tolan, T Ross Kelly

Org Lett· June 2005

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1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
John W Huffman, Simon M Bushell, John R A Miller, Jenny L Wiley, Billy R Martin

Bioorg Med Chem· December 2002

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A three-component coupling process based on vicarious nucleophilic substitution (VNS(AR))-alkylation reactions: an approach to indoprofen and derivatives.
Nicholas J Lawrence, John Liddle, Simon M Bushell, David A Jackson

J Org Chem· January 2002

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