Publications by authors named "Simon N Willis"

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The histone acetyltransferase KAT6B is required for hematopoietic stem cell development and function.
Maria I Bergamasco, Nishika Ranathunga, Waruni Abeysekera, Connie S N Li-Wai-Suen, Alexandra L Garnham, Simon N Willis

Stem Cell Reports· April 2024

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An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway.
Stephanie Trezise, Isabella Y Kong, Edwin D Hawkins, Marco J Herold, Simon N Willis

Front Immunol· March 2023

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Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis.
Isabella Y Kong, Stephanie Trezise, Amanda Light, Izabela Todorovski, Gisela Mir Arnau, Simon N Willis

Cell Death Differ· December 2022

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The transcription factor IRF4 represses proapoptotic BMF and BIM to licence multiple myeloma survival.
Pasquale L Fedele, Yang Liao, Jia-Nan Gong, Yuan Yao, Mark F van Delft, Simon N Willis

Leukemia· July 2021

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OBF1 and Oct factors control the germinal center transcriptional program.
Shuang Song, Chun Cao, Mohamed-Amin Choukrallah, Fengyuan Tang, Gerhard Christofori, Simon N Willis

Blood· May 2021

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IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis.
Michael Sze Yuan Low, Erica J Brodie, Pasquale L Fedele, Yang Liao, George Grigoriadis, Simon N Willis

Cell Rep· November 2019

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New players in the gene regulatory network controlling late B cell differentiation.
Simon N Willis, Stephen L Nutt

Curr Opin Immunol· June 2019

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IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos.
Pasquale L Fedele, Simon N Willis, Yang Liao, Michael S Low, Jai Rautela

Blood· November 2018

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A point mutation in the signal peptide impairs the development of innate lymphoid cell subsets.
Francisca F Almeida, Sara Tognarelli, Antoine Marçais, Andrew J Kueh, Miriam E Friede, Simon N Willis

Oncoimmunology· August 2018

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Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins.
Stephanie Trezise, Alexander Karnowski, Pasquale L Fedele, Sridurga Mithraprabhu, Yang Liao, Simon N Willis

Int J Mol Sci· July 2018

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Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB.
Simon N Willis, Julie Tellier, Yang Liao, Stephanie Trezise, Amanda Light

Nat Commun· November 2017

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NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.
Elisha de Valle, George Grigoriadis, Lorraine A O'Reilly, Simon N Willis, Mhairi J Maxwell

J Exp Med· April 2016

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Investigating the Antigen Specificity of Multiple Sclerosis Central Nervous System-Derived Immunoglobulins.
Simon N Willis, Panos Stathopoulos, Anne Chastre, Shannon D Compton, David A Hafler

Front Immunol· December 2015

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Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.
Wei Shi, Yang Liao, Simon N Willis, Nadine Taubenheim, Michael Inouye

Nat Immunol· June 2015

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The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
Sebastian Carotta, Simon N Willis, Jhagvaral Hasbold, Michael Inouye, Swee Heng Milon Pang

J Exp Med· October 2014

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Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism.
Simon N Willis, Kim L Good-Jacobson, Joan Curtis, Amanda Light, Julie Tellier

J Immunol· April 2014

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Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.
Luis Querol, Pamela L Clark, Mary A Bailey, Chris Cotsapas, Anne H Cross, Simon N Willis

Neurology· September 2013

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Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis.
Arundhati Ray, Anthony A Amato, Elizabeth M Bradshaw, Kevin J Felice, Daniel B DiCapua, Simon N Willis

PLoS One· April 2013

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Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin.
Birgit Obermeier, Laura Lovato, Reinhard Mentele, Wolfgang Brück, Ignasi Forne, Simon N Willis

J Neuroimmunol· April 2011

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Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis.
Laura Lovato, Simon N Willis, Scott J Rodig, Tyler Caron, Stefany E Almendinger

Brain· February 2011

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Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
Marc Kvansakul, Andrew H Wei, Jamie I Fletcher, Simon N Willis, Lin Chen

PLoS Pathog· December 2010

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Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain.
Simon N Willis, Christine Stadelmann, Scott J Rodig, Tyler Caron, Stefan Gattenloehner

Brain· December 2009

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The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response.
Simon N Willis, Scott S Mallozzi, Scott J Rodig, Katherine M Cronk, Shannon L McArdel

J Immunol· March 2009

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Immune surveillance of intracranial germ cell tumors.
Simon N Willis, Scott S Mallozzi, Kevin C O'Connor

MedLab Mag· January 2008

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A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.
Erinna F Lee, Peter E Czabotar, Mark F van Delft, Ewa M Michalak, Michelle J Boyle, Simon N Willis

J Cell Biol· January 2008

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