Publications by authors named "Simon P Williams"

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Whole-body CD8 T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study.
Janneke W de Boer, Kylie Keijzer, Jaap A van Doesum, Nienke A M Smit, Adrienne H Brouwers, Simon P Williams

Nat Commun· November 2025

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Heterogeneity of CD8 T-Cell Changes in Advanced Melanomas After Initiation of Immunotherapy.
Jahlisa S Hooiveld-Noeken, Laura Kist de Ruijter, Pim P van de Donk, Lotte M Smit, Marjolijn N Lub-de Hooge, Simon P Williams

J Nucl Med· September 2025

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Effects of Pretargeting and FcRn Binding Abrogation on the Biodistribution of a One-Armed Antibody-Based T Cell Imaging Agent.
Danielle Mandikian, Lauren Sermeño, Rachana Ohri, Pragya Adhikari, Christopher W Davies, Simon P Williams

Bioconjug Chem· August 2025

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Development of an F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Shravan Kumar Sriraman, Christopher W Davies, Herman Gill, James R Kiefer, Jianping Yin, Simon Peter Williams

Eur J Nucl Med Mol Imaging· February 2023

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Whole-body CD8 T cell visualization before and during cancer immunotherapy: a phase 1/2 trial.
Laura Kist de Ruijter, Pim P van de Donk, Jahlisa S Hooiveld-Noeken, Danique Giesen, Sjoerd G Elias, Simon P Williams

Nat Med· December 2022

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Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics.
Hanine Rafidi, Alberto Estevez, Gregory Z Ferl, Danielle Mandikian, Shannon Stainton, Simon P Williams

Mol Cancer Ther· October 2021

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Imaging Patients with Metastatic Castration-Resistant Prostate Cancer Using Zr-DFO-MSTP2109A Anti-STEAP1 Antibody.
Jorge A Carrasquillo, Bernard M Fine, Neeta Pandit-Taskar, Steven M Larson, Stephen E Fleming, Simon P Williams

J Nucl Med· November 2019

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Pharmacokinetics and Biodistribution of a [Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients.
Joseph A O'Donoghue, Daniel C Danila, Neeta Pandit-Taskar, Volkan Beylergil, Sarah M Cheal, Simon P Williams

Mol Pharm· July 2019

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Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis.
Gail D Lewis Phillips, Merry C Nishimura, Jennifer Arca Lacap, Samir Kharbanda, Elaine Mai, Simon P Williams

Breast Cancer Res Treat· August 2017

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Evaluation of a 3-hydroxypyridin-2-one (2,3-HOPO) Based Macrocyclic Chelator for (89)Zr(4+) and Its Use for ImmunoPET Imaging of HER2 Positive Model of Ovarian Carcinoma in Mice.
Jeff N Tinianow, Darpan N Pandya, Sylvie L Pailloux, Annie Ogasawara, Alexander N Vanderbilt, Simon-P Williams

Theranostics· December 2016

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ImmunoPET with Anti-Mesothelin Antibody in Patients with Pancreatic and Ovarian Cancer before Anti-Mesothelin Antibody-Drug Conjugate Treatment.
Laetitia E Lamberts, Catharina W Menke-van der Houven van Oordt, Eva J ter Weele, Frederike Bensch, Michiel M Smeenk, Simon P Williams

Clin Cancer Res· April 2016

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Imaging the distribution of an antibody-drug conjugate constituent targeting mesothelin with ⁸⁹Zr and IRDye 800CW in mice bearing human pancreatic tumor xenografts.
Eva J ter Weele, Anton G T Terwisscha van Scheltinga, Jos G W Kosterink, Linda Pot, Silke R Vedelaar, Simon P Williams

Oncotarget· December 2015

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Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia.
Yu Ouyang, Martin S Judenhofer, Jeffrey H Walton, Jan Marik, Simon P Williams

J Vis Exp· September 2015

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An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.
Steven R Leong, Wei-Ching Liang, Yan Wu, Lisa Crocker, Eric Cheng, Simon P Williams

Mol Pharm· June 2015

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Antibody positron emission tomography imaging in anticancer drug development.
Laetitia E Lamberts, Simon P Williams, Anton G T Terwisscha van Scheltinga, Marjolijn N Lub-de Hooge, Carolien P Schröder

J Clin Oncol· May 2015

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Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies.
C Andrew Boswell, Jan Marik, Michael J Elowson, Noe A Reyes, Sheila Ulufatu, Simon P Williams

J Med Chem· December 2013

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Pharmacokinetics and biodistribution of a human monoclonal antibody to oxidized LDL in cynomolgus monkey using PET imaging.
Amrita V Kamath, Simon P Williams, Sherry Bullens, Kyra J Cowan, Yvonne Stenberg

PLoS One· February 2013

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Effects of anti-VEGF on pharmacokinetics, biodistribution, and tumor penetration of trastuzumab in a preclinical breast cancer model.
Cinthia V Pastuskovas, Eduardo E Mundo, Simon P Williams, Tapan K Nayak, Jason Ho

Mol Cancer Ther· March 2012

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The development of peptide-based tools for the analysis of angiogenesis.
Anna Fedorova, Kerry Zobel, Herman S Gill, Annie Ogasawara, Judith E Flores, Simon-P Williams

Chem Biol· July 2011

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Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET.
Jeff N Tinianow, Herman S Gill, Annie Ogasawara, Judith E Flores, Alexander N Vanderbilt, Simon-P Williams

Nucl Med Biol· April 2010

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A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2.
Herman S Gill, Jeff N Tinianow, Annie Ogasawara, Judith E Flores, Alexander N Vanderbilt, Simon-P Williams

J Med Chem· October 2009

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PET of glial metabolism using 2-18F-fluoroacetate.
Jan Marik, Annie Ogasawara, Baby Martin-McNulty, Jed Ross, Judith E Flores, Simon P Williams

J Nucl Med· June 2009

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Reactive hyperemia and BOLD MRI demonstrate that VEGF inhibition, age, and atherosclerosis adversely affect functional recovery in a murine model of peripheral artery disease.
Joan M Greve, Simon P Williams, Lisa J Bernstein, Hope Goldman, Franklin V Peale

J Magn Reson Imaging· October 2008

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Quantification of viable tumor microvascular characteristics by multispectral analysis.
Leanne R Berry, Kai H Barck, Mary Ann Go, Jed Ross, Xiumin Wu, Simon P Williams

Magn Reson Med· July 2008

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In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitis.
Bittoo Kanwar, Dong Wei Gao, Andrew B Hwang, James P Grenert, Simon P Williams

J Immunol Methods· January 2008

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