Publications by authors named "Simon Peace"

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A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1.
Leonie Müller, Amy K Burton, Chloe L Tayler, James E Rowedder, Jonathan P Hutchinson, Simon Peace

SLAS Discov· January 2023

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UV-Induced 1,3,4-Oxadiazole Formation from 5-Substituted Tetrazoles and Carboxylic Acids in Flow.
Luke Green, Keith Livingstone, Sophie Bertrand, Simon Peace, Craig Jamieson

Chemistry· November 2020

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Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.
Hannah V Woodcock, Jessica D Eley, Delphine Guillotin, Manuela Platé, Carmel B Nanthakumar, Simon Peace

Nat Commun· September 2020

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Correction to Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway.
Heather Hobbs, Gianpaolo Bravi, Ian Campbell, Maire Convery, Hannah Davies, Simon Peace

J Med Chem· October 2019

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Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway.
Heather Hobbs, Gianpaolo Bravi, Ian Campbell, Maire Convery, Hannah Davies, Simon Peace

J Med Chem· August 2019

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The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis.
Hannah V Woodcock, Jessica D Eley, Delphine Guillotin, Manuela Platé, Carmel B Nanthakumar, Simon Peace

Nat Commun· January 2019

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Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.
Nick Barton, Máire Convery, Anthony W J Cooper, Kenneth Down, J Nicole Hamblin, Simon Peace

J Med Chem· December 2018

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Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Augustin Amour, Nick Barton, Anthony W J Cooper, Graham Inglis, Craig Jamieson, Simon Peace

J Med Chem· October 2016

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Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Augustin Amour, Nick Barton, Anthony W J Cooper, Graham Inglis, Craig Jamieson, Simon Peace

J Med Chem· September 2016

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Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
Augustin Amour, Nick Barton, Anthony W J Cooper, Graham Inglis, Craig Jamieson, Simon Peace

J Med Chem· August 2016

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In vivo activity of an azole series of CCR2 antagonists.
Chris A Smethurst, Nicola Bevan, Carl Brooks, Amanda Emmons, Peter J Gough, Simon Peace

Bioorg Med Chem Lett· December 2012

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Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.
Alan D Borthwick, John Liddle, Dave E Davies, Anne M Exall, Christopher Hamlett, Simon Peace

J Med Chem· January 2012

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Identification of a sulfonamide series of CCR2 antagonists.
Simon Peace, Joanne Philp, Carl Brooks, Val Piercy, Kitty Moores

Bioorg Med Chem Lett· July 2010

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The discovery of GSK221149A: a potent and selective oxytocin antagonist.
John Liddle, Michael J Allen, Alan D Borthwick, David P Brooks, David E Davies, Simon Peace

Bioorg Med Chem Lett· January 2008

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Three groups good, four groups bad? Atropisomerism in ortho-substituted diaryl ethers.
Mark S Betson, Jonathan Clayden, Christopher P Worrall, Simon Peace

Angew Chem Int Ed Engl· September 2006

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Investigation of bradykinin metabolism in human and rat plasma in the presence of the dual ACE/NEP inhibitors GW660511X and omapatrilat.
Olivier Heudi, Cesar Ramirez-Molina, Peter Marshall, Augustin Amour, Simon Peace

J Pept Sci· November 2002

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