Publications by authors named "Simon Pernot"

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Corrigendum to 'Impact on survival without chemotherapy of local treatments of lung metastasis of colorectal cancers: Analysis on REPULCO cohort' [Digestive and Liver Disease 56 (2024) 1930-7].
Lola-Jade Palmieri, Yaniss Belaroussi, Noémie Huchet, Marianne Fonck, Carine Bellera, Simon Pernot

Dig Liver Dis· November 2025

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Comprehensive molecular landscape of anal squamous cell carcinoma: analysis of tissue and liquid biopsies from 1844 patients.
Cristina Smolenschi, Saumya D Sisoudiya, Antoine Hollebecque, Smruthy Sivakumar, Meagan Montesion, Simon Pernot

NPJ Precis Oncol· November 2025

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Plasma Protein Biomarkers to Detect Early Gastric Preneoplasia and Cancer: A Prospective Study.
Quentin Giai Gianetto, Valérie Michel, Thibaut Douché, Karine Nozeret, Aziz Zaanan, Simon Pernot

Int J Mol Sci· October 2025

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Efficacy of immunotherapy in gastrointestinal (GI) tumors with mismatch repair deficient (MMRd) unusual phenotype: an AGEO real-world study.
Emily Alouani, Julien Taieb, David Tougeron, Guillaume Roces, Antoine Hollebecque, Simon Pernot

J Immunother Cancer· October 2025

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Prognostic impact of the BRAF V600E mutation in patients with MSI-high metastatic colorectal cancer treated with immune checkpoint inhibitors.
Claire Gallois, Margherita Ambrosini, Sara Lonardi, Emily Alouani, Rosine Guimbaud, Simon Pernot

Eur J Cancer· September 2025

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Real-world efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient biliary tract cancer: An AGEO study.
Iona Campo-Le-Brun, Emma Grapinet, Valerie Aurillac, Antoine Hollebecque, Pauline Parent, Simon Pernot

Eur J Cancer· September 2025

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TFOX versus FOLFOX in first-line treatment of patients with advanced HER2-negative gastric or gastro-oesophageal junction adenocarcinoma (PRODIGE 51- FFCD-GASTFOX): an open-label, multicentre, randomised, phase 3 trial.
Aziz Zaanan, Olivier Bouché, Christelle de la Fouchardière, Karine Le Malicot, Simon Pernot

Lancet Oncol· June 2025

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Predictive and prognostic factors of efficacy of third-line chemotherapy in patients with unresectable pancreatic cancer: a cohort-based study.
Camille Evrard, Antoine Pelras, Simon Rivet, Jean-Baptiste Bachet, Olivier Dubreuil, Simon Pernot

Oncologist· June 2025

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Inhibition of PCSK9 Attenuates Liver Endothelial Cell Activation Induced by Colorectal Cancer Stem Cells During Liver Metastasis.
Ander Martin, Daniela Gerovska, Marcos J Arauzo-Bravo, Maitane Duarte García-Escudero, Helena García García, Simon Pernot

Cancers (Basel)· June 2025

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Regorafenib plus avelumab in advanced gastroenteropancreatic neuroendocrine neoplasms: a phase 2 trial and correlative analysis.
Sophie Cousin, Jean-Philippe Guégan, Lola Jade Palmieri, Jean Philippe Metges, Simon Pernot

Nat Cancer· April 2025

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Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer.
Béatrice Demoures, Fabienne Soulet, Jean Descarpentrie, Isabel Galeano-Otero, José Sanchez Collado, Simon Pernot

EMBO Mol Med· March 2025

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Extensive molecular profiling of KRAS wild-type as compared to KRAS mutated pancreatic ductal adenocarcinoma on 318 patients.
Jeanne Lena, Mélissa Alamé, Antoine Italiano, Isabelle Soubeyran, Laura Blouin, Simon Pernot

Eur J Cancer· February 2025

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Early treatment discontinuation in patients with deficient mismatch repair or microsatellite instability high metastatic colorectal cancer receiving immune checkpoint inhibitors.
Julien Taieb, Margherita Ambrosini, Emily Alouani, Sara Lonardi, Frank A Sinicrope, Simon Pernot

J Immunother Cancer· January 2025

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Impact on survival without chemotherapy of local treatments of lung metastasis of colorectal cancers: Analysis on REPULCO cohort.
Lola-Jade Palmieri, Yaniss Belaroussi, Noémie Huchet, Marianne Fonck, Carine Bellera, Simon Pernot

Dig Liver Dis· November 2024

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Phase I/II study of trifluridine/tipiracil plus XB2001 versus trifluridine/tipiracil in metastatic colorectal cancer.
Jean-David Fumet, Nicolas Roussot, Aurélie Bertaut, Emeric Limagne, Marion Thibaudin, Simon Pernot

Future Oncol· November 2024

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BRAF + EGFR +/- MEK inhibitors after immune checkpoint inhibitors in BRAF V600E mutated and deficient mismatch repair or microsatellite instability high metastatic colorectal cancer.
Margherita Ambrosini, David Tougeron, Dominik Modest, Rosine Guimbaud, Scott Kopetz, Simon Pernot

Eur J Cancer· October 2024

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Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.
Sophie Cousin, Jean-Philippe Guégan, Kohei Shitara, Lola Jade Palmieri, Jean Philippe Metges, Simon Pernot

Mol Cancer· September 2024

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A multicenter study evaluating efficacy of immune checkpoint inhibitors in advanced non-colorectal digestive cancers with microsatellite instability.
Mathilde Moreau, Emily Alouani, Clémence Flecchia, Antoine Falcoz, Claire Gallois, Simon Pernot

Eur J Cancer· May 2024

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Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world study.
Clémence Flecchia, Edouard Auclin, Emily Alouani, Mathilde Mercier, Antoine Hollebecque, Simon Pernot

Br J Cancer· February 2024

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Echoendoscopic ultrasound pancreatic adenocarcinoma diagnosis and theranostic approach: should mutation research be recommended in everyday practice?
Dominique Béchade, Lola-Jade Palmieri, Benjamin Bonhomme, Simon Pernot, Jeanne Léna

Therap Adv Gastroenterol· January 2024

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Sulconazole inhibits PD-1 expression in immune cells and cancer cells malignant phenotype through NF-κB and calcium activity repression.
Simon Pernot, Mercedes Tomé, Isabel Galeano-Otero, Serge Evrard, Iker Badiola

Front Immunol· January 2024

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Adjuvant chemotherapy benefit according to T and N stage in small bowel adenocarcinoma: a large retrospective multicenter study.
Aziz Zaanan, Julie Henriques, Anthony Turpin, Sylvain Manfredi, Romain Coriat, Simon Pernot

JNCI Cancer Spectr· August 2023

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DCF versus doublet chemotherapy as first-line treatment of advanced squamous anal cell carcinoma: a multicenter propensity score-matching study.
Stefano Kim, Véronique Vendrely, Angélique Saint, Thierry André, Pauline Vaflard, Simon Pernot

Exp Hematol Oncol· July 2023

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One-Year Follow-Up of Seroprevalence of SARS-CoV-2 Infection and Anxiety among Health Workers of a French Cancer Center: The PRO-SERO-COV Study.
Brice Richez, Coralie Cantarel, Françoise Durrieu, Isabelle Soubeyran, Julie Blanchi, Simon Pernot

Int J Environ Res Public Health· May 2023

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AGR2 protein expression in colorectal tumour epithelialcompartment.
Eric Chevet, F Bassal, Stéphanie Beq, Benjamin Bonhomme, Emeric Boisteau, Simon Pernot

Gut· December 2022

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