Publications by authors named "Simona Iezzi"

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Immunotherapy in melanoma: advances, pitfalls, and future perspectives.
Cristina Sorino, Simona Iezzi, Ludovica Ciuffreda, Italia Falcone

Front Mol Biosci· June 2024

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HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response.
Cinzia Pisani, Annalisa Onori, Francesca Gabanella, Simona Iezzi, Roberta De Angelis

Biochim Biophys Acta Mol Cell Res· January 2024

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AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation.
Matteo Caforio, Nicola Tumino, Cristina Sorino, Isabella Manni, Stefano Di Giovenale, Simona Iezzi

Front Immunol· October 2023

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CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity.
Valeria Catena, Tiziana Bruno, Simona Iezzi, Silvia Matteoni, Annalisa Salis

J Exp Clin Cancer Res· July 2021

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Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma.
Tiziana Bruno, Francesca De Nicola, Giacomo Corleone, Valeria Catena, Frauke Goeman, Simona Iezzi

Blood Adv· November 2020

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Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Cristina Sorino, Valeria Catena, Tiziana Bruno, Francesca De Nicola, Stefano Scalera, Simona Iezzi

Nucleic Acids Res· June 2020

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Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia.
Valentina Folgiero, Cristina Sorino, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Simona Iezzi

EMBO Rep· March 2018

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Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization.
Tiziana Bruno, Mariacristina Valerio, Luca Casadei, Francesca De Nicola, Frauke Goeman, Simona Iezzi

J Exp Clin Cancer Res· February 2017

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Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells.
Valeria Catena, Tiziana Bruno, Francesca De Nicola, Frauke Goeman, Matteo Pallocca, Simona Iezzi

Oncotarget· October 2016

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Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins.
Tiziana Bruno, Simona Iezzi, Maurizio Fanciulli

Front Oncol· February 2016

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Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Agata Desantis, Tiziana Bruno, Valeria Catena, Francesca De Nicola, Frauke Goeman, Simona Iezzi

EMBO J· May 2015

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Discovering Che-1/AATF: a new attractive target for cancer therapy.
Simona Iezzi, Maurizio Fanciulli

Front Genet· April 2015

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Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization.
Cristina Sorino, Tiziana Bruno, Agata Desantis, Maria Grazia Di Certo, Simona Iezzi

J Biol Chem· August 2013

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Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.
Tiziana Bruno, Agata Desantis, Gianluca Bossi, Silvia Di Agostino, Cristina Sorino, Simona Iezzi

Cancer Cell· August 2010

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The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.
Francesca De Nicola, Tiziana Bruno, Simona Iezzi, Monica Di Padova, Aristide Floridi

J Biol Chem· July 2007

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NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death.
Maria Grazia Di Certo, Nicoletta Corbi, Tiziana Bruno, Simona Iezzi, Francesca De Nicola

J Cell Sci· June 2007

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Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Tiziana Bruno, Francesca De Nicola, Simona Iezzi, Daniele Lecis, Carmen D'Angelo

Cancer Cell· December 2006

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Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.
Simona Iezzi, Monica Di Padova, Carlo Serra, Giuseppina Caretti, Cristiano Simone

Dev Cell· May 2004

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Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Monica Di Padova, Tiziana Bruno, Francesca De Nicola, Simona Iezzi, Carmen D'Angelo

J Biol Chem· September 2003

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Functional interaction of the subunit 3 of RNA polymerase II (RPB3) with transcription factor-4 (ATF4).
Roberta De Angelis, Simona Iezzi, Tiziana Bruno, Nicoletta Corbi, Monica Di Padova

FEBS Lett· July 2003

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Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.
Marcella Fulco, R Louis Schiltz, Simona Iezzi, M Todd King, Po Zhao

Mol Cell· July 2003

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The alpha-like RNA polymerase II core subunit 3 (RPB3) is involved in tissue-specific transcription and muscle differentiation via interaction with the myogenic factor myogenin.
Nicoletta Corbi, Monica Di Padova, Roberta De Angelis, Tiziana Bruno, Valentina Libri, Simona Iezzi

FASEB J· October 2002

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Slug is a novel downstream target of MyoD. Temporal profiling in muscle regeneration.
Po Zhao, Simona Iezzi, Ethan Carver, Devin Dressman, Thomas Gridley

J Biol Chem· August 2002

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Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases.
Simona Iezzi, Giulio Cossu, Clara Nervi, Vittorio Sartorelli, Pier Lorenzo Puri

Proc Natl Acad Sci U S A· May 2002

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