Publications by authors named "Simone A Melander"

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Targeting the root cause of obesity-related comorbidities through weight independent and dependent actions on insulin sensitivity: Benefits of dual amylin and calcitonin receptor agonists.
Anna Thorsø Larsen, Simone Anna Melander, Khaled Elhady Mohamed, Emilie Ahmt Petersen, Meryem Benmarce

Biomed Pharmacother· September 2025

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DACRA induces profound weight loss, satiety control, and increased mitochondrial respiratory capacity in adipose tissue.
Emilie A Petersen, Ida Blom, Simone A Melander, Mays Al-Rubai, Marina Vidotto

Int J Obes (Lond)· October 2024

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The enduring metabolic improvement of combining dual amylin and calcitonin receptor agonist and semaglutide treatments in a rat model of obesity and diabetes.
Anna Thorsø Larsen, Khaled Elhady Mohamed, Simone Anna Melander, Morten Asser Karsdal, Kim Henriksen

Am J Physiol Endocrinol Metab· August 2024

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Are insulin sensitizers the new strategy to treat Type 1 diabetes? A long-acting dual amylin and calcitonin receptor agonist improves insulin-mediated glycaemic control and controls body weight.
Simone Anna Melander, Anna Thorsø Larsen, Morten Asser Karsdal, Kim Henriksen

Br J Pharmacol· June 2024

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OXM-104, a potential candidate for the treatment of obesity, NASH and type 2 diabetes.
Simone Anna Melander, Ashref Kayed, Kim Vietz Andreassen, Morten Asser Karsdal, Kim Henriksen

Eur J Pharmacol· January 2024

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Dual amylin and calcitonin receptor agonist treatment reduces biomarkers associated with kidney fibrosis in diabetic rats.
Simone Anna Melander, Alexandra Louise Møller, Khaled Elhady Mohamed, Daniel Guldager Kring Rasmussen, Federica Genovese

Am J Physiol Endocrinol Metab· November 2023

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Dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss.
Anna Thorsø Larsen, Simone A Melander, Nina Sonne, Emma Bredtoft, Mays Al-Rubai

Biomed Pharmacother· August 2023

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The Effects of Dual GLP-1/Glucagon Receptor Agonists with Different Receptor Selectivity in Mouse Models of Obesity and Nonalcoholic Steatohepatitis.
Ashref Kayed, Simone Anna Melander, Suheb Khan, Kim Vietz Andreassen, Morten Asser Karsdal

J Pharmacol Exp Ther· March 2023

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Improved metabolic efficacy of a dual amylin and calcitonin receptor agonist when combined with semaglutide or empagliflozin.
Simone A Melander, Anna Katri, Morten A Karsdal, Kim Henriksen

Eur J Pharmacol· January 2023

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