Publications by authors named "Simone Baltrusch"

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Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy.
Eric Lieberwirth, Anja Schaeper, Regina Lange, Ingo Barke, Simone Baltrusch

Beilstein J Nanotechnol· June 2025

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Effects of coding variants in the glucokinase regulatory protein gene on hepatic glucose and triglyceride metabolism suggest a gene regulatory function of glucokinase.
Sara Langer, David Jagdhuhn, Rica Waterstradt, Jessica Gromoll, Michael Müller, Simone Baltrusch

Metabolism· May 2025

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Automated in-depth fiber and nuclei typing in cross-sectional muscle images can pave the way to a better understanding of skeletal muscle diseases.
Simone Baltrusch

Acta Physiol (Oxf)· September 2023

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The novel GCK variant p.Val455Leu associated with hyperinsulinism is susceptible to allosteric activation and is conducive to weight gain and the development of diabetes.
Sara Langer, Rica Waterstradt, Georg Hillebrand, René Santer, Simone Baltrusch

Diabetologia· December 2021

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The Role of Neurotropic B Vitamins in Nerve Regeneration.
Simone Baltrusch

Biomed Res Int· September 2021

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MiD51 Is Important for Maintaining Mitochondrial Health in Pancreatic Islet and MIN6 Cells.
Julia Schultz, Jeanette Warkus, Carmen Wolke, Rica Waterstradt, Simone Baltrusch

Front Endocrinol (Lausanne)· May 2021

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Collagen Remodeling Plays a Pivotal Role in Endothelial Corneal Dystrophies.
Marcus Walckling, Rica Waterstradt, Simone Baltrusch

Invest Ophthalmol Vis Sci· December 2020

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6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase and small chemical activators affect enzyme activity of activating glucokinase mutants by distinct mechanisms.
Sara Langer, Anke Hofmeister-Brix, Rica Waterstradt, Simone Baltrusch

Biochem Pharmacol· October 2019

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Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
Jan Niemann, Cindy Zehm, Rica Waterstradt, Markus Tiedge, Simone Baltrusch

Cell Calcium· September 2019

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Mitochondrial complex IV mutation increases reactive oxygen species production and reduces lifespan in aged mice.
Gesine Reichart, Johannes Mayer, Cindy Zehm, Timo Kirschstein, Tursonjan Tokay, Simone Baltrusch

Acta Physiol (Oxf)· April 2019

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An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle.
Jan Niemann, Cindy Johne, Susanne Schröder, Franziska Koch, Saleh M Ibrahim, Simone Baltrusch

Free Radic Biol Med· January 2017

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Early detection of diabetic neuropathy by investigating CNFL and IENFD in thy1-YFP mice.
Janine Leckelt, Pedro Guimarães, Annett Kott, Alfredo Ruggeri, Oliver Stachs, Simone Baltrusch

J Endocrinol· November 2016

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Polymorphisms of the murine mitochondrial ND4, CYTB and COX3 genes impact hematopoiesis during aging.
Christin Kretzschmar, Catrin Roolf, Katrin Timmer, Anett Sekora, Gudrun Knübel, Simone Baltrusch

Oncotarget· November 2016

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Polymorphism in Murine mtATP8 Gene Correlates with Decreased Reactive Oxygen Species in Aging Hematopoietic Cells.
Catrin Roolf, Christin Kretzschmar, Katrin Timmer, Anett Sekora, Gudrun Knübel, Simone Baltrusch

In Vivo· November 2016

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Age-Related Changes in Murine Corneal Nerves.
Maria Reichard, Heike Weiss, Enea Poletti, Alfredo Ruggeri, Rudolf F Guthoff, Simone Baltrusch

Curr Eye Res· August 2016

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Precise expression of Fis1 is important for glucose responsiveness of beta cells.
Julia Schultz, Rica Waterstradt, Tobias Kantowski, Annekatrin Rickmann, Florian Reinhardt, Simone Baltrusch

J Endocrinol· July 2016

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Drp1 guarding of the mitochondrial network is important for glucose-stimulated insulin secretion in pancreatic beta cells.
Florian Reinhardt, Julia Schultz, Rica Waterstradt, Simone Baltrusch

Biochem Biophys Res Commun· June 2016

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In vivo nonlinear imaging of corneal structures with special focus on BALB/c and streptozotocin-diabetic Thy1-YFP mice.
Tobias Ehmke, Janine Leckelt, Maria Reichard, Heike Weiss, Marina Hovakimyan, Simone Baltrusch

Exp Eye Res· May 2016

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Mitochondrial network regulation and its potential interference with inflammatory signals in pancreatic beta cells.
Simone Baltrusch

Diabetologia· April 2016

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Diabetic foot syndrome and corneal subbasal nerve plexus changes in congolese patients with type 2 diabetes.
Andrey Zhivov, Sabine Peschel, Hans-Christof Schober, Oliver Stachs, Simone Baltrusch

PLoS One· March 2016

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Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants.
Johannes Mayer, Gesine Reichart, Tursonjan Tokay, Falko Lange, Simone Baltrusch

PLoS One· March 2016

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Characterization of two MODY2 mutations with different susceptibility to activation.
Sara Langer, Christian Platz, Rica Waterstradt, Simone Baltrusch

Biochem Biophys Res Commun· September 2015

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Systems biology approaches in aging research.
Anuradha Chauhan, Ulf W Liebal, Julio Vera, Simone Baltrusch, Christian Junghanß

Interdiscip Top Gerontol· July 2015

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Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.
Matthew G Rees, Anne Raimondo, Jian Wang, Matthew R Ban, Mindy I Davis, Simone Baltrusch

Hum Mol Genet· October 2014

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Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching.
Mark Moeller, Misa Hirose, Sarah Mueller, Catrin Roolf, Simone Baltrusch

Aging Cell· August 2014

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