Publications by authors named "Simone Barattucci"

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TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD.
Brian J Joseph, Kelly A Marshall, Peter Harley, Jacob R Mann, Francesco Alessandrini, Simone Barattucci

Nat Neurosci· December 2025

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TDP-43 loss induces cryptic polyadenylation in ALS/FTD.
Sam Bryce-Smith, Anna-Leigh Brown, Max Z Y J Chien, Dario Dattilo, Puja R Mehta, Simone Barattucci

Nat Neurosci· November 2025

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U7 small nuclear RNA splice-switching therapeutics for STMN2 and UNC13A in Amyotrophic Lateral Sclerosis.
Puja R Mehta, Tomas Solomon, Sarah Pickles, Peter Harley, Michela Barioglio, Simone Barattucci

bioRxiv· November 2025

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TDP-43 pathology induces CD8 T cell activation through cryptic epitope recognition.
Shahab Chizari, Matteo Zanovello, Steven Kong, Vidur Saigal, Anna-Leigh Brown, Simone Barattucci

bioRxiv· July 2025

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Axon guidance genes are regulated by TDP-43 and RGNEF through long-intron removal.
Yasmine Abbassi, Sara Cappelli, Eugenio Spagnolo, Alice Gennari, Giulia Visani, Simone Barattucci

FASEB J· October 2024

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Creation of de novo cryptic splicing for ALS and FTD precision medicine.
Oscar G Wilkins, Max Z Y J Chien, Josette J Wlaschin, Simone Barattucci, Peter Harley

Science· October 2024

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Loss of TDP-43 induces synaptic dysfunction that is rescued by splice-switching ASOs.
Matthew J Keuss, Peter Harley, Eugeni Ryadnov, Rachel E Jackson, Matteo Zanovello, Simone Barattucci

bioRxiv· June 2024

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TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD.
Sam Bryce-Smith, Anna-Leigh Brown, Puja R Mehta, Francesca Mattedi, Alla Mikheenko, Simone Barattucci

bioRxiv· January 2024

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Neuropathology of the Basal Ganglia in SNCA Transgenic Rat Model of Parkinson's Disease: Involvement of Parvalbuminergic Interneurons and Glial-Derived Neurotropic Factor.
Emanuela Paldino, Vincenza D'angelo, Mariangela Massaro Cenere, Ezia Guatteo, Simone Barattucci

Int J Mol Sci· September 2022

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Unraveling the toxic effects mediated by the neurodegenerative disease-associated S375G mutation of TDP-43 and its S375E phosphomimetic variant.
Francesca Paron, Simone Barattucci, Sara Cappelli, Maurizio Romano, Christian Berlingieri

J Biol Chem· August 2022

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