Publications by authors named "Simone Denis"

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Targeting phospholipase PLAG-15 promotes healthy aging in via lysosomal-related genes.
Sanne van der Rijt, Marte Molenaars, Rashmi Kamble, Weisha Li, Bauke V Schomakers, Simone W Denis

iScience· July 2025

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Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay.
Berith M Balfoort, Gioena Pampalone, Jos P N Ruiter, Simone W Denis, Marion M Brands

Mol Genet Metab· October 2024

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Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS.
Signe Mosegaard, Krishna S Twayana, Simone W Denis, Jeffrey Kroon, Bauke V Schomakers

FASEB Bioadv· September 2024

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Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis

Sci Rep· June 2024

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Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis

Sci Rep· May 2024

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Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis

bioRxiv· February 2024

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Tracer-based lipidomics enables the discovery of disease-specific candidate biomarkers in mitochondrial β-oxidation disorders.
Marit Schwantje, Signe Mosegaard, Suzan J G Knottnerus, Jan Bert van Klinken, Ronald J Wanders, Simone W Denis

FASEB J· February 2024

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Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis.
Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas

Cells· December 2022

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Neonatal Long-Chain 3-Ketoacyl-CoA Thiolase deficiency: Clinical-biochemical phenotype, sodium-D,L-3-hydroxybutyrate treatment experience and cardiac evaluation using speckle echocardiography.
Annemarijne R J Veenvliet, Mark R Garrelfs, Floris E A Udink Ten Cate, Sacha Ferdinandusse, Simone Denis

Mol Genet Metab Rep· June 2022

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Time-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle.
Paul de Goede, Rob C I Wüst, Bauke V Schomakers, Simone Denis, Frédéric M Vaz

FASEB J· February 2022

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Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy.
Adrianus J Bakermans, S Matthijs Boekholdt, Dylan K de Vries, Yolan J Reckman, Emile S Farag, Simone W Denis

J Magn Reson Imaging· August 2021

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Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity.
Rebecca L McIntyre, Simone W Denis, Rashmi Kamble, Marte Molenaars, Michael Petr

Aging Cell· August 2021

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Reduced nicotinamide mononucleotide is a new and potent NAD precursor in mammalian cells and mice.
Rubén Zapata-Pérez, Alessandra Tammaro, Bauke V Schomakers, Angelique M L Scantlebery, Simone Denis

FASEB J· April 2021

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ACOX3 Dysfunction as a Potential Cause of Recurrent Spontaneous Vasospasm of Internal Carotid Artery.
Joon-Tae Kim, So Yeon Won, KyungWook Kang, Sang-Hoon Kim, Man-Seok Park, Simone W Denis

Transl Stroke Res· October 2020

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Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function.
Yiran Li, Wenjia Lou, Vaishnavi Raja, Simone Denis, Wenxi Yu

J Biol Chem· July 2019

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Barth syndrome cells display widespread remodeling of mitochondrial complexes without affecting metabolic flux distribution.
Iliana A Chatzispyrou, Sergio Guerrero-Castillo, Ntsiki M Held, Jos P N Ruiter, Simone W Denis

Biochim Biophys Acta Mol Basis Dis· November 2018

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A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.
Jeroen Baardman, Sanne G S Verberk, Koen H M Prange, Michel van Weeghel, Saskia van der Velden, Simone W Denis

Cell Rep· November 2018

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Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B.
Michel van Weeghel, Desiree Abdurrachim, Rianne Nederlof, Carmen A Argmann, Riekelt H Houtkooper, Simone Denis

Cardiovasc Res· August 2018

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Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation.
Ntsiki M Held, Eline N Kuipers, Michel van Weeghel, Jan Bert van Klinken, Simone W Denis

Sci Rep· June 2018

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Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites.
Abhijit Babaji Shinde, Ritesh Kumar Baboota, Simone Denis, Ursula Loizides-Mangold, Annelies Peeters

Mitochondrion· March 2018

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A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase.
Sacha Ferdinandusse, Simone Denis, Carlo W T van Roermund, Mary Anne Preece, Janet Koster

Biochim Biophys Acta Mol Basis Dis· March 2018

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Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant.
Daniel J Pomerantz, Sacha Ferdinandusse, Joy Cogan, David N Cooper, Tyler Reimschisel, Simone Denis

Am J Med Genet A· March 2018

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Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart.
Rianne Nederlof, Simone Denis, Benjamin Lauzier, Christine Des Rosiers, Markku Laakso

Metabolism· July 2017

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A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3.
Sacha Ferdinandusse, Gerardo Jimenez-Sanchez, Janet Koster, Simone Denis, Carlo W Van Roermund

Hum Mol Genet· January 2015

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