Publications by authors named "Simone Filosto"

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Facts and Hopes: CAR T-Cell Therapy and Immune Contexture in Non-Hodgkin Lymphoma.
Assia Hijazi, Frederick L Locke, Nathalie Scholler, Mike Mattie, Simone Filosto

Clin Cancer Res· September 2025

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Clinical, tumor, and product features associated with outcomes after axicabtagene ciloleucel therapy in follicular lymphoma.
Soumya Poddar, Jiali Yan, Gayatri Tiwari, Darawan Rinchai, Justin Budka, Simone Filosto

J Clin Invest· August 2025

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Intrinsic immunosuppressive features of monocytes suppress CAR-T19 through IL-1 pathway modulation in mantle cell lymphoma.
Kun Yun, R Leo Sakemura, Ismail Can, Omar Gutierrez Ruiz, Ekene J Ogbodo, Simone Filosto

Mol Ther Oncol· June 2025

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Single-cell dynamics of breakthrough toxicities after anakinra prophylaxis for axicabtagene ciloleucel in lymphoma.
Matthew J Frigault, Ning Yao, Trisha R Berger, Marc Wehrli, Kathleen M E Gallagher, Simone Filosto

Blood Adv· May 2025

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Tumor gene expression signatures associated with outcome in large B-cell lymphoma treated with CD19-directed CAR T-cell therapy (axicabtagene ciloleucel).
Yuan Tian, Justin Budka, Frederick L Locke, Jason R Westin, Christina To, Simone Filosto

Front Oncol· February 2025

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Investigating the Influence of Covariates on Axicabtagene Ciloleucel (axi-cel) Kinetics in Patients with Non-Hodgkin's Lymphoma.
Magali Chartier, Simone Filosto, Thomas Peyret, Manoj Chiney, Francesca Milletti

Clin Pharmacokinet· September 2024

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IL-4 drives exhaustion of CD8 CART cells.
Carli M Stewart, Elizabeth L Siegler, R Leo Sakemura, Michelle J Cox, Truc Huynh, Simone Filosto

Nat Commun· September 2024

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Axicabtagene ciloleucel vs standard of care in second-line large B-cell lymphoma: outcomes by metabolic tumor volume.
Frederick L Locke, Olalekan O Oluwole, John Kuruvilla, Catherine Thieblemont, Franck Morschhauser, Simone Filosto

Blood· June 2024

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Impact of tumor microenvironment on efficacy of anti-CD19 CAR T cell therapy or chemotherapy and transplant in large B cell lymphoma.
Frederick L Locke, Simone Filosto, Justin Chou, Saran Vardhanabhuti, Regis Perbost

Nat Med· February 2024

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Product Attributes of CAR T-cell Therapy Differentially Associate with Efficacy and Toxicity in Second-line Large B-cell Lymphoma (ZUMA-7).
Simone Filosto, Saran Vardhanabhuti, Miguel A Canales, Xavier Poiré, Lazaros J Lekakis

Blood Cancer Discov· January 2024

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Axicabtagene Ciloleucel in Combination with the 4-1BB Agonist Utomilumab in Patients with Relapsed/Refractory Large B-Cell Lymphoma: Phase 1 Results from ZUMA-11.
Michael D Jain, David B Miklos, Caron A Jacobson, John M Timmerman, Jennifer Sun, Simone Filosto

Clin Cancer Res· October 2023

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Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma.
Jason R Westin, Olalekan O Oluwole, Marie José Kersten, David B Miklos, Miguel-Angel Perales, Simone Filosto

N Engl J Med· July 2023

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Safety and Efficacy of Axicabtagene Ciloleucel versus Standard of Care in Patients 65 Years of Age or Older with Relapsed/Refractory Large B-Cell Lymphoma.
Jason R Westin, Frederick L Locke, Michael Dickinson, Armin Ghobadi, Mahmoud Elsawy, Simone Filosto

Clin Cancer Res· May 2023

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Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma.
Frederick L Locke, David B Miklos, Caron A Jacobson, Miguel-Angel Perales, Marie-José Kersten, Simone Filosto

N Engl J Med· February 2022

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High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers.
Simon J Anderhub, Grace Wing-Yan Mak, Mark D Gurden, Amir Faisal, Konstantinos Drosopoulos, Simone Filosto

Mol Cancer Ther· October 2019

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Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation.
Jennifer M Bratt, Kevin Y Chang, Michelle Rabowsky, Lisa M Franzi, Sean P Ott, Simone Filosto

J Immunol· June 2018

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Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist

Nat Med· June 2017

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Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist

Nat Med· April 2017

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PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist

Nat Med· November 2016

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Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium.
Samuel Chung, Simon Vu, Simone Filosto, Tzipora Goldkorn

Am J Respir Cell Mol Biol· June 2015

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Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.
Tzipora Goldkorn, Simone Filosto, Samuel Chung

Antioxid Redox Signal· November 2014

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Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy.
Benjamin B Davis, Amir A Zeki, Jennifer M Bratt, Lei Wang, Simone Filosto

Eur Respir J· August 2013

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Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells.
Simone Filosto, David S Baston, Samuel Chung, Cathleen R Becker, Tzipora Goldkorn

Mol Cancer Ther· August 2013

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Lung cancer and lung injury: the dual role of ceramide.
Tzipora Goldkorn, Samuel Chung, Simone Filosto

Handb Exp Pharmacol· July 2013

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Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.
Simone Filosto, Cathleen R Becker, Tzipora Goldkorn

Mol Cancer Ther· April 2012

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