Publications by authors named "Simone Gaedicke"

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Author Correction: Expansion of circulating stem-like CD8 T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice.
Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu

Nat Commun· August 2024

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Hypofractionated radiotherapy combined with lenalidomide improves systemic antitumor activity in mouse solid tumor models.
Kateryna Onyshchenko, Ren Luo, Xi Rao, Xuanwei Zhang, Simone Gaedicke

Theranostics· April 2024

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Adding liposomal doxorubicin enhances the abscopal effect induced by radiation/αPD1 therapy depending on tumor cell mitochondrial DNA and cGAS/STING.
Liqun Wang, Ren Luo, Kateryna Onyshchenko, Xi Rao, Meidan Wang, Simone Gaedicke

J Immunother Cancer· August 2023

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Expansion of circulating stem-like CD8 T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice.
Kateryna Onyshchenko, Ren Luo, Elena Guffart, Simone Gaedicke, Anca-Ligia Grosu

Nat Commun· April 2023

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Necroptosis-dependent Immunogenicity of Cisplatin: Implications for Enhancing the Radiation-induced Abscopal Effect.
Ren Luo, Kateryna Onyshchenko, Liqun Wang, Simone Gaedicke, Anca-Ligia Grosu

Clin Cancer Res· February 2023

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Immune cell infiltration pattern in non-small cell lung cancer PDX models is a model immanent feature and correlates with a distinct molecular and phenotypic make-up.
Eva Oswald, Daniel Bug, Anne Grote, Kanstantsin Lashuk, Nassim Bouteldja, Simone Gaedicke

J Immunother Cancer· April 2022

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Deep abscopal response to radiotherapy and anti-PD-1 in an oligometastatic melanoma patient with unfavorable pretreatment immune signature.
Tsubasa Watanabe, Elke Firat, Jutta Scholber, Simone Gaedicke, Corinne Heinrich

Cancer Immunol Immunother· September 2020

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Adding Indoximod to Hypofractionated Radiotherapy with Anti-PD-1 Checkpoint Blockade Enhances Early NK and CD8 T-Cell-Dependent Tumor Activity.
Tsubasa Watanabe, Simone Gaedicke, Elena Guffart, Elke Firat, Gabriele Niedermann

Clin Cancer Res· February 2020

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Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment.
Ren Luo, Elke Firat, Simone Gaedicke, Elena Guffart, Tsubasa Watanabe

Clin Cancer Res· December 2019

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Combination treatment with hypofractionated radiotherapy plus IL-2/anti-IL-2 complexes and its theranostic evaluation.
Hua Jing, Michael Hettich, Simone Gaedicke, Elke Firat, Mark Bartholomä

J Immunother Cancer· February 2019

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Imaging and Selective Elimination of Glioblastoma Stem Cells with Theranostic Near-Infrared-Labeled CD133-Specific Antibodies.
Hua Jing, Claudia Weidensteiner, Wilfried Reichardt, Simone Gaedicke, Xuekai Zhu

Theranostics· October 2017

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Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model.
Nadja Osterberg, Napoleone Ferrara, Jean Vacher, Simone Gaedicke, Gabriele Niedermann

Neuro Oncol· July 2016

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Effective Eradication of Glioblastoma Stem Cells by Local Application of an AC133/CD133-Specific T-cell-Engaging Antibody and CD8 T Cells.
Shruthi Prasad, Simone Gaedicke, Marcia Machein, Gerhard Mittler, Friederike Braun

Cancer Res· June 2015

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Patient-derived glioblastoma stem cells are killed by CD133-specific CAR T cells but induce the T cell aging marker CD57.
Xuekai Zhu, Shruthi Prasad, Simone Gaedicke, Michael Hettich, Elke Firat

Oncotarget· January 2015

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Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells.
Simone Gaedicke, Friederike Braun, Shruthi Prasad, Marcia Machein, Elke Firat

Proc Natl Acad Sci U S A· February 2014

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Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells.
Elke Firat, Astrid Weyerbrock, Simone Gaedicke, Anca-Ligia Grosu, Gabriele Niedermann

PLoS One· March 2013

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Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells.
Elke Firat, Simone Gaedicke, Chizuko Tsurumi, Norbert Esser, Astrid Weyerbrock

Radiat Oncol· June 2011

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Non-invasive in vivo imaging of tumor-associated CD133/prominin.
Chizuko Tsurumi, Norbert Esser, Elke Firat, Simone Gaedicke, Marie Follo

PLoS One· December 2010

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Viability and DNA damage responses of TPPII-deficient Myc- and Ras-transformed fibroblasts.
Chizuko Tsurumi, Elke Firat, Simone Gaedicke, Jisen Huai, Pankaj Kumar Mandal

Biochem Biophys Res Commun· September 2009

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Tripeptidyl peptidase II plays a role in the radiation response of selected primary cell types but not based on nuclear translocation and p53 stabilization.
Elke Firat, Chizuko Tsurumi, Simone Gaedicke, Jisen Huai, Gabriele Niedermann

Cancer Res· April 2009

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Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Jisen Huai, Elke Firat, Ahmed Nil, Daniele Million, Simone Gaedicke

Proc Natl Acad Sci U S A· April 2008

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Analysis of direct and cross-presentation of antigens in TPPII knockout mice.
Elke Firat, Jisen Huai, Loredana Saveanu, Simone Gaedicke, Peter Aichele

J Immunol· December 2007

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The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation.
Elke Firat, Loredana Saveanu, Peter Aichele, Peter Staeheli, Jisen Huai, Simone Gaedicke

J Immunol· February 2007

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Differential proteasomal processing of hydrophobic and hydrophilic protein regions: contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef.
Maria Lucchiari-Hartz, Viv Lindo, Niclas Hitziger, Simone Gaedicke, Loredana Saveanu

Proc Natl Acad Sci U S A· June 2003

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Antitumor effect of the human immunodeficiency virus protease inhibitor ritonavir: induction of tumor-cell apoptosis associated with perturbation of proteasomal proteolysis.
Simone Gaedicke, Elke Firat-Geier, Oana Constantiniu, Maria Lucchiari-Hartz, Marina Freudenberg

Cancer Res· December 2002

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