Publications by authors named "Simone Gastaldi"

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Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury.
Simone Gastaldi, Magalì Giordano, Federica Blua, Chiara Rubeo, Valentina Boscaro

Vascul Pharmacol· September 2024

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Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma.
Federica Blua, Chiara Monge, Simone Gastaldi, Nausicaa Clemente, Stefania Pizzimenti

Bioorg Chem· March 2024

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Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation.
Simone Gastaldi, Carmine Rocca, Eleonora Gianquinto, Maria Concetta Granieri, Valentina Boscaro

Eur J Med Chem· September 2023

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Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF Protein.
Elisabetta Marini, Marco Marino, Giulia Gionfriddo, Federica Maione, Marta Pandini, Simone Gastaldi

Molecules· December 2022

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Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor.
Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F Sandall, Marta Giorgis

Molecules· June 2021

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Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity.
Massimo Bertinaria, Simone Gastaldi, Elisabetta Marini, Marta Giorgis

Arch Biochem Biophys· July 2019

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A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation.
Carolina Pellegrini, Matteo Fornai, Rocchina Colucci, Laura Benvenuti, Vanessa D’Antongiovanni, Simone Gastaldi

Front Pharmacol· December 2018

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