Publications by authors named "Simone Haupt"

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Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory.
Bastian Nießing, Yannik Breitkreuz, Andreas Elanzew, Marcelo A S de Toledo, Peter Vajs, Simone Haupt

Front Bioeng Biotechnol· September 2024

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Emergence of nociceptive functionality and opioid signaling in human induced pluripotent stem cell-derived sensory neurons.
Pascal Röderer, Andreea Belu, Luzia Heidrich, Maike Siobal, Jörg Isensee, Simone Haupt

Pain· August 2023

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High-content phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons using machine learning classification.
Aurore Vuidel, Loïc Cousin, Beatrice Weykopf, Simone Haupt, Zahra Hanifehlou

Stem Cell Reports· October 2022

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Dynamics of Metabolic Pathways and Stress Response Patterns during Human Neural Stem Cell Proliferation and Differentiation.
Vesselina Semkova, Simone Haupt, Michaela Segschneider, Catherine Bell, Magnus Ingelman-Sundberg

Cells· April 2022

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Deep-learning-based multi-class segmentation for automated, non-invasive routine assessment of human pluripotent stem cell culture status.
Tobias Piotrowski, Oliver Rippel, Andreas Elanzew, Bastian Nießing, Sebastian Stucken, Simone Haupt

Comput Biol Med· February 2021

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Energy Metabolism Disturbances in Cell Models of PARK2 CNV Carriers with ADHD.
Viola Stella Palladino, Andreas G Chiocchetti, Lukas Frank, Denise Haslinger, Rhiannon McNeill, Simone Haupt

J Clin Med· December 2020

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The StemCellFactory: A Modular System Integration for Automated Generation and Expansion of Human Induced Pluripotent Stem Cells.
Andreas Elanzew, Bastian Nießing, Daniel Langendoerfer, Oliver Rippel, Tobias Piotrowski, Simone Haupt

Front Bioeng Biotechnol· November 2020

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Induced pluripotent stem cell-based modeling of mutant LRRK2-associated Parkinson's disease.
Beatrice Weykopf, Simone Haupt, Johannes Jungverdorben, Lea Jessica Flitsch, Matthias Hebisch

Eur J Neurosci· February 2019

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Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.
Glyn N Stacey, Sandra Coecke, Anna-Bal Price, Lyn Healy, Paul Jennings, Simone Haupt

Adv Exp Med Biol· June 2017

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Impedimetric real-time monitoring of neural pluripotent stem cell differentiation process on microelectrode arrays.
Diana Seidel, Janine Obendorf, Beate Englich, Heinz-Georg Jahnke, Vesselina Semkova, Simone Haupt

Biosens Bioelectron· December 2016

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TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
Benjamin M Schwenk, Hannelore Hartmann, Alperen Serdaroglu, Martin H Schludi, Daniel Hornburg, Simone Haupt

EMBO J· November 2016

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Spatial and temporal control of cell aggregation efficiently directs human pluripotent stem cells towards neural commitment.
Cláudia C Miranda, Tiago G Fernandes, Jorge F Pascoal, Simone Haupt, Oliver Brüstle

Biotechnol J· October 2015

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A reproducible and versatile system for the dynamic expansion of human pluripotent stem cells in suspension.
Andreas Elanzew, Annika Sommer, Annette Pusch-Klein, Oliver Brüstle, Simone Haupt

Biotechnol J· October 2015

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Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells.
Tiago G Fernandes, Sofia T Duarte, Mehrnaz Ghazvini, Cláudia Gaspar, Diana C Santos, Simone Haupt

Biotechnol J· October 2015

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Integrated platform for production and purification of human pluripotent stem cell-derived neural precursors.
Gonçalo M C Rodrigues, Andreia F S Matos, Tiago G Fernandes, Carlos A V Rodrigues, Michael Peitz, Simone Haupt

Stem Cell Rev Rep· April 2014

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Automated selection and harvesting of pluripotent stem cell colonies.
Simone Haupt, Jan Grützner, Marc-Christian Thier, Tobias Kallweit, Barbara Helen Rath

Biotechnol Appl Biochem· October 2013

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Non-genetic modulation of Notch activity by artificial delivery of Notch intracellular domain into neural stem cells.
Simone Haupt, Lodovica Borghese, Oliver Brüstle, Frank Edenhofer

Stem Cell Rev Rep· September 2012

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Laser-assisted photoablation of human pluripotent stem cells from differentiating cultures.
Stefanie Terstegge, Franziska Winter, Barbara H Rath, Iris Laufenberg, Claudia Schwarz, Simone Haupt

Stem Cell Rev Rep· June 2010

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Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.
Lodovica Borghese, Dasa Dolezalova, Thoralf Opitz, Simone Haupt, Anke Leinhaas

Stem Cells· May 2010

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Defining maximum levels of higher alcohols in alcoholic beverages and surrogate alcohol products.
Dirk W Lachenmeier, Simone Haupt, Katja Schulz

Regul Toxicol Pharmacol· April 2008

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Stage-specific conditional mutagenesis in mouse embryonic stem cell-derived neural cells and postmitotic neurons by direct delivery of biologically active Cre recombinase.
Simone Haupt, Frank Edenhofer, Michael Peitz, Anke Leinhaas, Oliver Brüstle

Stem Cells· January 2007

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Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells.
Gisela Tünnemann, Robert M Martin, Simone Haupt, Christoph Patsch, Frank Edenhofer

FASEB J· September 2006

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Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase.
Lars Nolden, Frank Edenhofer, Simone Haupt, Philipp Koch, F Thomas Wunderlich

Nat Methods· June 2006

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