Publications by authors named "Simone Kayser"

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Case Report: A Multi-Peptide Vaccine Targeting Individual Somatic Mutations Induces Tumor Infiltration of Neoantigen-Specific T Cells in a Patient with Metastatic Colorectal Cancer.
Armin Rabsteyn, Henning Zelba, Borong Shao, Lisa Oenning, Christina Kyzirakos, Simone Kayser

Vaccines (Basel)· September 2025

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In-depth characterization of vaccine-induced neoantigen-specific T cells in patients with IDH1-mutant glioma undergoing personalized peptide vaccination.
Henning Zelba, Borong Shao, Armin Rabsteyn, Annekathrin Reinhardt, Carsten Greve, Simone Kayser

J Immunother Cancer· June 2025

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A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine.
Pauline Latzer, Henning Zelba, Florian Battke, Annekathrin Reinhardt, Borong Shao, Simone Kayser

Nat Commun· August 2024

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Case Report: Long-Term Survival of a Patient with Cerebral Metastasized Ovarian Carcinoma Treated with a Personalized Peptide Vaccine and Anti-PD-1 Therapy.
Henning Zelba, Christina Kyzirakos, Simone Kayser, Borong Shao, Annekathrin Reinhardt

Vaccines (Basel)· April 2024

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Case Report: Targeting of individual somatic tumor mutations by multipeptide vaccination tailored for HLA class I and II presentation induces strong CD4 and CD8 T-cell responses in a patient with metastatic castration sensitive prostate cancer.
Henning Zelba, Armin Rabsteyn, Oliver Bartsch, Christina Kyzirakos, Simone Kayser

Front Immunol· November 2023

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Adjuvant Treatment for Breast Cancer Patients Using Individualized Neoantigen Peptide Vaccination-A Retrospective Observation.
Henning Zelba, Alex McQueeney, Armin Rabsteyn, Oliver Bartsch, Christina Kyzirakos, Simone Kayser

Vaccines (Basel)· November 2022

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A Highly Specific Assay for the Detection of SARS-CoV-2-Reactive CD4 and CD8 T Cells in COVID-19 Patients.
Henning Zelba, David Worbs, Johannes Harter, Natalia Pieper, Christina Kyzirakos-Feger, Simone Kayser

J Immunol· February 2021

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Use of plasma ctDNA as a potential biomarker for longitudinal monitoring of a patient with metastatic high-risk upper tract urothelial carcinoma receiving pembrolizumab and personalized neoepitope-derived multipeptide vaccinations: a case report.
Carolin Blumendeller, Julius Boehme, Maximilian Frick, Martin Schulze, Antje Rinckleb, Simone Kayser

J Immunother Cancer· January 2021

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T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
Judith Feucht, Simone Kayser, David Gorodezki, Mohamad Hamieh, Michaela Döring

Oncotarget· November 2016

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Identification of a Novel Immunodominant HLA-B*07: 02-restricted Adenoviral Peptide Epitope and Its Potential in Adoptive Transfer Immunotherapy.
Patrick S Günther, Janet K Peper, Benjamin Faist, Simone Kayser, Lena Hartl

J Immunother· September 2015

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Rapid generation of NY-ESO-1-specific CD4 T1 cells for adoptive T-cell therapy.
Simone Kayser, Cristina Boβ, Judith Feucht, Kai-Erik Witte, Alexander Scheu

Oncoimmunology· May 2015

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Adoptive T-cell therapy with hexon-specific Th1 cells as a treatment of refractory adenovirus infection after HSCT.
Judith Feucht, Kathrin Opherk, Peter Lang, Simone Kayser, Lena Hartl

Blood· March 2015

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Induction of Thelper1-driven antiviral T-cell lines for adoptive immunotherapy is determined by differential expression of IFN-γ and T-cell activation markers.
Josef Leibold, Judith Feucht, Ameli Halder, Stefan Stevanovic, Simone Kayser

J Immunother· March 2013

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Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.
Vanya Icheva, Simone Kayser, Daniel Wolff, Sebastian Tuve, Christina Kyzirakos

J Clin Oncol· January 2013

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Pre-existing T-cell immunity against mucin-1 in breast cancer patients and healthy volunteers.
Brigitte Gückel, Christine Rentzsch, Maria-Dorothea Nastke, Alexander Marmé, Ines Gruber, Simone Kayser

J Cancer Res Clin Oncol· April 2006

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Evaluation of pre-existent immunity in patients with primary breast cancer: molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells.
Christine Rentzsch, Simone Kayser, Susanne Stumm, Iris Watermann, Steffen Walter

Clin Cancer Res· October 2003

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Tumor-associated antigen profiling in breast and ovarian cancer: mRNA, protein or T cell recognition?
Simone Kayser, Iris Watermann, Christine Rentzsch, Toni Weinschenk, Diethelm Wallwiener

J Cancer Res Clin Oncol· July 2003

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