Publications by authors named "Simone Lubrano"

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Inhibition of anti-apoptotic BCL2 overcomes adaptive resistance to co-targeting of the protein kinase FAK and MEK in GNAQ-driven uveal melanoma.
Simone Lubrano, Rodolfo Daniel Cervantes-Villagrana, Nadia Arang, Adam Officer, Sendi Rafael Adame-Garcia

J Biol Chem· October 2025

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FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma.
Simone Lubrano, Rodolfo Daniel Cervantes-Villagrana, Farhoud Faraji, Sydney Ramirez, Kuniaki Sato

Cancer Cell· March 2025

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Correction: The landscape of BRAF transcript and protein variants in human cancer.
Andrea Marranci, Zhijie Jiang, Marianna Vitiello, Elena Guzzolino, Laura Comelli, Simone Lubrano

Mol Cancer· February 2025

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High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Nadia Arang, Simone Lubrano, Michele Ceribelli, Damiano C Rigiracciolo, Robert Saddawi-Konefka

Cell Rep Med· November 2023

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Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ-focal adhesion kinase signaling circuitry.
Nadia Arang, Simone Lubrano, Damiano Cosimo Rigiracciolo, Daniela Nachmanson, Scott M Lippman

J Biol Chem· February 2023

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Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).
Damiano Cosimo Rigiracciolo, Nijiro Nohata, Rosamaria Lappano, Francesca Cirillo, Marianna Talia, Simone Lubrano

J Exp Clin Cancer Res· June 2022

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Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for -Driven Uveal Melanoma.
Justine S Paradis, Monica Acosta, Robert Saddawi-Konefka, Ayush Kishore, Simone Lubrano

Clin Cancer Res· August 2021

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Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for -Driven Uveal Melanoma.
Justine S Paradis, Monica Acosta, Robert Saddawi-Konefka, Ayush Kishore, Frederico Gomes, Simone Lubrano

Clin Cancer Res· June 2021

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Early modifications of circulating microRNAs levels in metastatic colorectal cancer patients treated with regorafenib.
Marta Schirripa, Beatrice Borelli, Romina D'Aurizio, Simone Lubrano, Chiara Cremolini

Pharmacogenomics J· October 2019

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A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK.
Xiaodong Feng, Nadia Arang, Damiano Cosimo Rigiracciolo, Joo Sang Lee, Huwate Yeerna, Simone Lubrano

Cancer Cell· March 2019

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Development of a yeast-based system to identify new hBRAFV600E functional interactors.
Simone Lubrano, Laura Comelli, Chiara Piccirilli, Andrea Marranci, Francesca Dapporto

Oncogene· February 2019

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Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells.
Marianna Vitiello, Andrea Tuccoli, Romina D'Aurizio, Samanta Sarti, Laura Giannecchini, Simone Lubrano

Oncotarget· April 2017

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The landscape of BRAF transcript and protein variants in human cancer.
Andrea Marranci, Zhijie Jiang, Marianna Vitiello, Elena Guzzolino, Laura Comelli, Simone Lubrano

Mol Cancer· April 2017

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Identification of BRAF 3'UTR Isoforms in Melanoma.
Andrea Marranci, Andrea Tuccoli, Marianna Vitiello, Elisa Mercoledi, Samanta Sarti, Simone Lubrano

J Invest Dermatol· June 2015

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