Publications by authors named "Simone Melega"

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Rituximab pediatric drug development: Pharmacokinetic and pharmacodynamic modeling to inform regulatory approval for rituximab treatment in patients with granulomatosis with polyangiitis or microscopic polyangiitis.
Candice Jamois, Leonid Gibiansky, Clarisse Chavanne, Melissa Cheu, Patricia B Lehane, Simone Melega

Clin Transl Sci· September 2022

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Evaluation of Serious Infection in Pediatric Patients with Low Immunoglobulin Levels Receiving Rituximab for Granulomatosis with Polyangiitis or Microscopic Polyangiitis.
Simone Melega, Paul Brogan, Gavin Cleary, Aimee O Hersh, Ozgur Kasapcopur

Rheumatol Ther· April 2022

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Phase IIa Global Study Evaluating Rituximab for the Treatment of Pediatric Patients With Granulomatosis With Polyangiitis or Microscopic Polyangiitis.
Paul Brogan, Rae S M Yeung, Gavin Cleary, Satyapal Rangaraj, Ozgur Kasapcopur, Simone Melega

Arthritis Rheumatol· January 2022

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Risk of Malignancies in Patients with Rheumatoid Arthritis Treated with Rituximab: Analyses of Global Postmarketing Safety Data and Long-Term Clinical Trial Data.
Paul Emery, Daniel E Furst, Petra Kirchner, Simone Melega, Stuart Lacey

Rheumatol Ther· March 2020

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Rituximab utilization for approved and off-label nononcology indications and patients' experiences with the Patient Alert Card.
Khaled Sarsour, Senam Beckley-Kartey, Simone Melega, Adefowope Odueyungbo, Petra Kirchner

Pharmacol Res Perspect· February 2020

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Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Marcelo Dutra Arbo, Simone Melega, Regina Stöber, Markus Schug, Eugen Rempel

Arch Toxicol· December 2016

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Bile canalicular dynamics in hepatocyte sandwich cultures.
Raymond Reif, Johan Karlsson, Georgia Günther, Lynette Beattie, David Wrangborg, Simone Melega

Arch Toxicol· October 2015

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Anti-diabetic properties of a non-conventional radical scavenger, as compared to pioglitazone and exendin-4, in streptozotocin-nicotinamide diabetic mice.
Michela Novelli, Donatella Canistro, Manuela Martano, Niccola Funel, Andrea Sapone, Simone Melega

Eur J Pharmacol· April 2014

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Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
Simone Melega, Donatella Canistro, Eleonora Pagnotta, Renato Iori, Andrea Sapone

Mutat Res· February 2013

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On enzyme-based anticancer molecular dietary manipulations.
Andrea Sapone, Donatella Canistro, Simone Melega, Ramona Moles, Fabio Vivarelli

J Biomed Biotechnol· January 2013

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Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences.
Donatella Canistro, Jessica Barillari, Simone Melega, Andrea Sapone, Renato Iori

Food Chem Toxicol· August 2012

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Modulation of cytochrome P450 and induction of DNA damage in Cyprinus carpio exposed in situ to surface water treated with chlorine or alternative disinfectants in different seasons.
Donatella Canistro, Simone Melega, Dario Ranieri, Andrea Sapone, Bianca Gustavino

Mutat Res· January 2012

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