Publications by authors named "Simone Schimmer"

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Iron improves the antiviral activity of NK cells.
Simone Schimmer, Vaasudevan Sridhar, Zelal Satan, Anton Grebe, Mohamed Saad

Front Immunol· May 2025

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Dietary lipid overload creates a suppressive environment that impedes the antiviral functions of NK cells.
Simone Schimmer, Leonie Kerkmann, Nele Kahlert, Shahd Al Jubeh, Tanja Werner

iScience· May 2025

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Fatty acids are crucial to fuel NK cells upon acute retrovirus infection.
Simone Schimmer, Daniela Mittermüller, Tanja Werner, Paul E Görs, Sven W Meckelmann

Front Immunol· December 2023

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The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10 Regulatory T Cells During Acute Retroviral Infection.
Elisabeth Littwitz-Salomon, Anna Malyshkina, Simone Schimmer, Ulf Dittmer

Front Immunol· September 2019

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Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance.
Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Jean Alexander Ross, Annette Paschen, Simone Schimmer

Cancer Immunol Immunother· March 2019

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Friend retrovirus infection induces the development of memory-like natural killer cells.
Elisabeth Littwitz-Salomon, Thanh Nguyen, Simone Schimmer, Ulf Dittmer

Retrovirology· October 2018

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Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells.
Limei Shen, Stefan Tenzer, Moritz Hess, Ute Distler, Ingrid Tubbe, Simone Schimmer

PLoS One· April 2018

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Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses.
Elisabeth Littwitz-Salomon, Simone Schimmer, Ulf Dittmer

J Virol· November 2017

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Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.
Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Gennadiy Zelinskyy, Sonja Windmann, Simone Schimmer

Sci Rep· August 2017

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Natural killer T cells contribute to the control of acute retroviral infection.
Elisabeth Littwitz-Salomon, Simone Schimmer, Ulf Dittmer

Retrovirology· January 2017

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Filariae-Retrovirus Co-infection in Mice is Associated with Suppressed Virus-Specific IgG Immune Response and Higher Viral Loads.
Kirsten Katrin Dietze, Ulf Dittmer, Daniel Karim Koudaimi, Simone Schimmer, Martina Reitz

PLoS Negl Trop Dis· December 2016

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Characterization of the Treg Response in the Hepatitis B Virus Hydrodynamic Injection Mouse Model.
Kirsten K Dietze, Simone Schimmer, Freya Kretzmer, Junzhong Wang, Yong Lin

PLoS One· August 2016

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Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads.
Kirsten K Dietze, Gennadiy Zelinskyy, Jia Liu, Freya Kretzmer, Simone Schimmer

PLoS Pathog· September 2014

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Tumor-specific CD4+ T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells.
Ilseyar Akhmetzyanova, Gennadiy Zelinskyy, Simone Schimmer, Sven Brandau, Petra Altenhoff

Cancer Immunol Immunother· February 2013

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Targeting viral antigens to CD11c on dendritic cells induces retrovirus-specific T cell responses.
Asim Ejaz, Christoph G Ammann, Roland Werner, Georg Huber, Verena Oberhauser, Simone Schimmer

PLoS One· February 2013

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Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes.
Wibke Bayer, Ruth Lietz, Teona Ontikatze, Lena Johrden, Matthias Tenbusch, Simone Schimmer

Retrovirology· September 2011

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Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points.
Kirsten K Dietze, Gennadiy Zelinskyy, Kathrin Gibbert, Simone Schimmer, Sandra Francois

Proc Natl Acad Sci U S A· February 2011

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Complement opsonization enhances friend virus infection of B cells and thereby amplifies the virus-specific CD8+ T cell response.
Custodio Bila, Verena Oberhauser, Christoph G Ammann, Asim Ejaz, Georg Huber, Simone Schimmer

J Virol· January 2011

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Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells.
Savita R Nair, Gennadiy Zelinskyy, Simone Schimmer, Nicole Gerlach, George Kassiotis

J Gen Virol· February 2010

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Vaccination with an adenoviral vector that encodes and displays a retroviral antigen induces improved neutralizing antibody and CD4+ T-cell responses and confers enhanced protection.
Wibke Bayer, Matthias Tenbusch, Ruth Lietz, Lena Johrden, Simone Schimmer

J Virol· February 2010

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The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.
Gennadiy Zelinskyy, Kirsten K Dietze, Yvonne P Hüsecken, Simone Schimmer, Savita Nair

Blood· October 2009

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Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity.
Matthias Tenbusch, Seraphin Kuate, Bettina Tippler, Nicole Gerlach, Simone Schimmer

BMC Immunol· April 2008

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Evaluation of the Friend Virus model for the development of improved adenovirus-vectored anti-retroviral vaccination strategies.
Wibke Bayer, Simone Schimmer, Dennis Hoffmann, Ulf Dittmer, Oliver Wildner

Vaccine· January 2008

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Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function.
Denise Pargmann, Raif Yücel, Christian Kosan, Ingrid Saba, Ludger Klein-Hitpass, Simone Schimmer

Eur J Immunol· December 2007

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The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen control.
Gennadiy Zelinskyy, Sandra Balkow, Simone Schimmer, Tanja Werner, Markus M Simon

J Virol· November 2007

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