Publications by authors named "Simone U Dalm"

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Illuminating radionuclide therapy response: Monitoring cancer cell and CAF survival in a direct 2D co-culture model.
Circe D van der Heide, Roisin McMorrow, Felipe Gama-Franceschi, Michail Doukas, Laura Mezzanotte, Simone U Dalm

Nucl Med Biol· November 2025

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Chemotherapy alters radiosensitivity and GRPR expression of prostate and breast cancer cells.
Tyrillshall S T Damiana, Lilian van den Brink, Lisette W de Kreij-de Bruin, Debra C Stuurman, Corrina M A de Ridder, Simone U Dalm

EJNMMI Res· August 2025

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Exploring the landscape of current in vitro and in vivo models and their relevance for targeted radionuclide theranostics.
Lisa Bokhout, Joana D Campeiro, Simone U Dalm

Eur J Nucl Med Mol Imaging· July 2025

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N-Terminal Stabilization of Radiolabeled Neurotensin Analogues for Improved Tumor Uptake.
Sacha Bodin, Tyrillshall S T Damiana, Santo Previti, Laure Balasse, Lina Ali, Simone U Dalm

J Med Chem· April 2025

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In vitro and ex vivo evaluation of preclinical models for FAP-targeted theranostics: differences and relevance for radiotracer evaluation.
Circe D van der Heide, Joana D Campeiro, Eline A M Ruigrok, Lilian van den Brink, Shashikanth Ponnala, Simone U Dalm

EJNMMI Res· December 2024

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In vitro and in vivo analyses of eFAP: a novel FAP-targeting small molecule for radionuclide theranostics and other oncological interventions.
Circe D van der Heide, Hanyue Ma, Mark W H Hoorens, Joana D Campeiro, Debra C Stuurman, Simone U Dalm

EJNMMI Radiopharm Chem· July 2024

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The Balance Between the Therapeutic Efficacy and Safety of [Lu]Lu-NeoB in a Preclinical Prostate Cancer Model.
Marjolein Verhoeven, Joost Haeck, Erik de Blois, Francesca Orlandi, Donato Barbato, Simone U Dalm

Mol Imaging Biol· February 2024

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Applying HDACis to increase SSTR2 expression and radiolabeled DOTA-TATE uptake: from cells to mice.
Maria J Klomp, Lilian van den Brink, Peter M van Koetsveld, Corrina M A de Ridder, Debra C Stuurman, Simone U Dalm

Life Sci· December 2023

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GRPR versus PSMA: expression profiles during prostate cancer progression demonstrate the added value of GRPR-targeting theranostic approaches.
Marjolein Verhoeven, Eline A M Ruigrok, Geert J L H van Leenders, Lilian van den Brink, Hayri E Balcioglu, Simone U Dalm

Front Oncol· August 2023

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Synthesis and Evaluation of ePSMA-DM1: A New Theranostic Small-Molecule Drug Conjugate (T-SMDC) for Prostate Cancer.
Erika Murce, Evelien Spaan, Savanne Beekman, Lilian van den Brink, Maryana Handula, Simone U Dalm

Pharmaceuticals (Basel)· July 2023

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Epigenetic regulation of SST expression in small intestinal neuroendocrine tumors.
Maria J Klomp, Julie Refardt, Peter M van Koetsveld, Claudia Campana, Simone U Dalm

Front Endocrinol (Lausanne)· May 2023

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Pre- and Intraoperative Visualization of GRPR-Expressing Solid Tumors: Preclinical Profiling of Novel Dual-Modality Probes for Nuclear and Fluorescence Imaging.
Marjolein Verhoeven, Maryana Handula, Lilian van den Brink, Corrina M A de Ridder, Debra C Stuurman, Simone U Dalm

Cancers (Basel)· April 2023

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Radionuclide imaging and therapy directed towards the tumor microenvironment: a multi-cancer approach for personalized medicine.
Circe D van der Heide, Simone U Dalm

Eur J Nucl Med Mol Imaging· November 2022

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Safety of [Lu]Lu-NeoB treatment: a preclinical study characterizing absorbed dose and acute, early, and late organ toxicity.
Eline A M Ruigrok, Marjolein Verhoeven, Mark W Konijnenberg, Erik de Blois, Corrina M A de Ridder, Simone U Dalm

Eur J Nucl Med Mol Imaging· November 2022

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The Effect of VPA Treatment on Radiolabeled DOTATATE Uptake: Differences Observed In Vitro and In Vivo.
Maria J Klomp, Leo J Hofland, Lilian van den Brink, Peter M van Koetsveld, Fadime Dogan, Simone U Dalm

Pharmaceutics· January 2022

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Towards Complete Tumor Resection: Novel Dual-Modality Probes for Improved Image-Guided Surgery of GRPR-Expressing Prostate Cancer.
Maryana Handula, Marjolein Verhoeven, Kuo-Ting Chen, Joost Haeck, Marion de Jong, Simone U Dalm

Pharmaceutics· January 2022

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GRPr Antagonist Ga-SB3 PET/CT Imaging of Primary Prostate Cancer in Therapy-Naïve Patients.
Ingrid L Bakker, Alida C Fröberg, Martijn B Busstra, J Fred Verzijlbergen, Mark Konijnenberg, Simone U Dalm

J Nucl Med· November 2021

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Radiolabeled Bombesin Analogs.
Rosalba Mansi, Berthold A Nock, Simone U Dalm, Martijn B Busstra, Wytske M van Weerden

Cancers (Basel)· November 2021

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Comparing the Effect of Multiple Histone Deacetylase Inhibitors on SSTR2 Expression and [In]In-DOTATATE Uptake in NET Cells.
Maria J Klomp, Simone U Dalm, Peter M van Koetsveld, Fadime Dogan, Marion de Jong

Cancers (Basel)· September 2021

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Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy.
Eline A M Ruigrok, Nicole van Vliet, Simone U Dalm, Erik de Blois, Dik C van Gent

Eur J Nucl Med Mol Imaging· May 2021

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Combination Therapy, a Promising Approach to Enhance the Efficacy of Radionuclide and Targeted Radionuclide Therapy of Prostate and Breast Cancer.
Tyrillshall S T Damiana, Simone U Dalm

Pharmaceutics· May 2021

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Cancer-Associated Fibroblasts as Players in Cancer Development and Progression and Their Role in Targeted Radionuclide Imaging and Therapy.
Sofia Koustoulidou, Mark W H Hoorens, Simone U Dalm, Shweta Mahajan, Reno Debets

Cancers (Basel)· March 2021

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Therapeutic Applications of Pretargeting.
Marjolein Verhoeven, Yann Seimbille, Simone U Dalm

Pharmaceutics· September 2019

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In Vivo Stabilized SB3, an Attractive GRPR Antagonist, for Pre- and Intra-Operative Imaging for Prostate Cancer.
Ingrid L Bakker, Sandra T van Tiel, Joost Haeck, Gabriela N Doeswijk, Erik de Blois, Simone U Dalm

Mol Imaging Biol· December 2018

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Comparing the therapeutic potential of thermosensitive liposomes and hyperthermia in two distinct subtypes of breast cancer.
Wouter J M Lokerse, Michiel Bolkestein, Simone U Dalm, Alexander M M Eggermont, Marion de Jong

J Control Release· July 2017

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